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6RFO
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BU of 6rfo by Molmil
ERK2 MAP kinase with the activation loop of p38alpha
Descriptor: Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1
Authors:Livnah, O, Eitan-Wexler, M.
Deposit date:2019-04-15
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295, 2020
6QYX
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BU of 6qyx by Molmil
p38(alpha) MAP kinase with the activation loop of ERK2
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Livnah, O, Eitan-Wexler, M, Vinograd, N.
Deposit date:2019-03-10
Release date:2020-04-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295, 2020
6QUE
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BU of 6que by Molmil
Structure of ovine transhydrogenase in the presence of NADP+ in a "single face-down" conformation
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Nicotinamide nucleotide transhydrogenase
Authors:Kampjut, D, Sazanov, L.A.
Deposit date:2019-02-27
Release date:2019-08-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure and mechanism of mitochondrial proton-translocating transhydrogenase.
Nature, 573, 2019
6QTI
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BU of 6qti by Molmil
Structure of ovine transhydrogenase in the presence of NADP+ in a "double face-down" conformation
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, DODECANE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Kampjut, D, Sazanov, L.A.
Deposit date:2019-02-25
Release date:2019-08-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and mechanism of mitochondrial proton-translocating transhydrogenase.
Nature, 573, 2019
6QCF
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BU of 6qcf by Molmil
Ovine respiratory complex I FRC open class 6
Descriptor: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QCA
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BU of 6qca by Molmil
Ovine respiratory complex I FRC open class 5
Descriptor: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC9
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BU of 6qc9 by Molmil
Ovine respiratory complex I FRC open class 4
Descriptor: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC8
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BU of 6qc8 by Molmil
Ovine respiratory complex I FRC open class 2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC7
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BU of 6qc7 by Molmil
Ovine respiratory complex I FRC open class 3
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC6
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BU of 6qc6 by Molmil
Ovine respiratory complex I FRC open class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC5
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BU of 6qc5 by Molmil
Ovine respiratory complex I FRC closed class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC4
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BU of 6qc4 by Molmil
Ovine respiratory supercomplex I+III2 open class 3
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein, Cytochrome b, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC3
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BU of 6qc3 by Molmil
Ovine respiratory supercomplex I+III2 open class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC2
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BU of 6qc2 by Molmil
Ovine respiratory supercomplex I+III2 open class 2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QBX
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BU of 6qbx by Molmil
Ovine respiratory supercomplex I+III2 closed class.
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-24
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QA9
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BU of 6qa9 by Molmil
Isolated complex I class refinement from Ovine respiratory supercomplex I+III2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-19
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6Q9E
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BU of 6q9e by Molmil
Complex III2 focused refinement from Ovine respiratory supercomplex I+III2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CARDIOLIPIN, Cytochrome b, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-18
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6Q9D
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BU of 6q9d by Molmil
CI Peripheral Arm focused refinement from Ovine respiratory SC I+III2
Descriptor: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-18
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6Q9B
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BU of 6q9b by Molmil
CI Membrane Arm focused refinement from Ovine respiratory SC I+III2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-17
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6OAT
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BU of 6oat by Molmil
Structure of the Ganjam virus OTU bound to sheep ISG15
Descriptor: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine
Authors:Dzimianski, J.V, Williams, I.L, Pegan, S.D.
Deposit date:2019-03-18
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Plos One, 14, 2019
6OAR
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BU of 6oar by Molmil
Structure of the Kupe virus OTU bound to the C-terminal domain of sheep ISG15
Descriptor: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine
Authors:Dzimianski, J.V, Williams, I.L, Pegan, S.D.
Deposit date:2019-03-18
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.063 Å)
Cite:Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Plos One, 14, 2019
6N6Y
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BU of 6n6y by Molmil
OXA-23 mutant F110A/M221A neutral pH form meropenem complex
Descriptor: Beta-lactamase oxa23, meropenem, bound form
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6X
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BU of 6n6x by Molmil
OXA-23 mutant F110A/M221A neutral pH form imipenem complex
Descriptor: Beta-lactamase oxa23, Imipenem, SULFATE ION
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6W
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BU of 6n6w by Molmil
OXA-23 mutant F110A/M221A neutral pH form
Descriptor: Beta-lactamase oxa23
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6V
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BU of 6n6v by Molmil
OXA-23 mutant F110A/M221A low pH form meropenem complex
Descriptor: Beta-lactamase, meropenem, bound form
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019

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數據於2024-06-12公開中

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