6LPB
| Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Kobayashi, K, Shihoya, W, Nishizawa, T, Nureki, O. | Deposit date: | 2020-01-09 | Release date: | 2020-03-11 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nat.Struct.Mol.Biol., 27, 2020
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6LQV
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6LQT
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6LQQ
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6LMK
| Cryo-EM structure of the human glucagon receptor in complex with Gs | Descriptor: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Qiao, A, Han, S, Tai, L, Sun, F, Zhao, Q, Wu, B. | Deposit date: | 2019-12-26 | Release date: | 2020-04-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
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6LQU
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6M1I
| CryoEM structure of human PAC1 receptor in complex with PACAP38 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | Deposit date: | 2020-02-26 | Release date: | 2020-03-11 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
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6MTB
| Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6MTD
| Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6MZM
| Human TFIID bound to promoter DNA and TFIIA | Descriptor: | SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | Deposit date: | 2018-11-05 | Release date: | 2018-11-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6MTE
| Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6MZD
| Human TFIID Lobe A canonical | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | Authors: | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | Deposit date: | 2018-11-05 | Release date: | 2018-11-28 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6NBI
| Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | Deposit date: | 2018-12-07 | Release date: | 2019-04-17 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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6NI3
| B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex | Descriptor: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. | Deposit date: | 2018-12-26 | Release date: | 2019-11-20 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
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6NIY
| A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | Descriptor: | Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M. | Deposit date: | 2019-01-02 | Release date: | 2019-01-23 | Last modified: | 2020-04-08 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2, 2019
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6NBH
| Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | Deposit date: | 2018-12-07 | Release date: | 2019-04-17 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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6ND4
| Conformational switches control early maturation of the eukaryotic small ribosomal subunit | Descriptor: | 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ... | Authors: | Hunziker, M, Barandun, J, Klinge, S. | Deposit date: | 2018-12-13 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Elife, 8, 2019
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6MZL
| Human TFIID canonical state | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | Authors: | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | Deposit date: | 2018-11-05 | Release date: | 2018-11-28 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6LQP
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6M1H
| CryoEM structure of human PAC1 receptor in complex with maxadilan | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | Deposit date: | 2020-02-26 | Release date: | 2020-03-11 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
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6M62
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6MTC
| Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6N4B
| Cannabinoid Receptor 1-G Protein Complex | Descriptor: | CHOLESTEROL, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Krishna Kumar, K, Shalev-Benami, M, Hu, H, Weis, W.I, Kobilka, B.K, Skiniotis, G. | Deposit date: | 2018-11-18 | Release date: | 2019-01-30 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex. Cell, 176, 2019
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6NBF
| Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | Descriptor: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | Deposit date: | 2018-12-07 | Release date: | 2019-04-17 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
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6DDF
| Mu Opioid Receptor-Gi Protein Complex | Descriptor: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Koehl, A, Hu, H, Maeda, S, Manglik, A, Kobilka, B.K, Skiniotis, G, Weis, W.I. | Deposit date: | 2018-05-10 | Release date: | 2018-06-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
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