3ORS
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![BU of 3ors by Molmil](/molmil-images/mine/3ors) | Crystal Structure of N5-Carboxyaminoimidazole Ribonucleotide Mutase from Staphylococcus aureus | Descriptor: | N5-Carboxyaminoimidazole Ribonucleotide Mutase, SULFATE ION | Authors: | Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. | Deposit date: | 2010-09-07 | Release date: | 2011-07-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
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3ORQ
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![BU of 3orq by Molmil](/molmil-images/mine/3orq) | Crystal Structure of N5-Carboxyaminoimidazole synthetase from Staphylococcus aureus complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Brugarolas, P, Duguid, E.M, Zhang, W, Poor, C.B, He, C. | Deposit date: | 2010-09-07 | Release date: | 2011-07-20 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr.,Sect.D, 67, 2011
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6NSO
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![BU of 6nso by Molmil](/molmil-images/mine/6nso) | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, IRON/SULFUR CLUSTER, Quinolinate synthase A | Authors: | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | Deposit date: | 2019-01-25 | Release date: | 2019-10-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
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6NSU
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![BU of 6nsu by Molmil](/molmil-images/mine/6nsu) | Crystallographic Capture of Quinolinate Synthase (NadA) from Pyrococcus horikoshii in its Substrates and Product-Bound States | Descriptor: | DIDEHYDROASPARTATE, IRON/SULFUR CLUSTER, Quinolinate synthase A | Authors: | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | Deposit date: | 2019-01-25 | Release date: | 2019-08-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
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8BPS
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![BU of 8bps by Molmil](/molmil-images/mine/8bps) | |
8BPL
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![BU of 8bpl by Molmil](/molmil-images/mine/8bpl) | |
4HXT
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![BU of 4hxt by Molmil](/molmil-images/mine/4hxt) | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR329 | Descriptor: | De Novo Protein OR329 | Authors: | Vorobiev, S, Su, M, Parmeggiani, F, Seetharaman, J, Huang, P.-S, Maglaqui, M, Xiao, X, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-11-12 | Release date: | 2012-11-21 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Computational design of self-assembling cyclic protein homo-oligomers. NAT.CHEM., 9, 2017
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4FYM
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![BU of 4fym by Molmil](/molmil-images/mine/4fym) | |
8RAK
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![BU of 8rak by Molmil](/molmil-images/mine/8rak) | |
3C3N
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![BU of 3c3n by Molmil](/molmil-images/mine/3c3n) | Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y | Descriptor: | Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Pinheiro, M.P, Iulek, J, Nonato, M.C. | Deposit date: | 2008-01-28 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain Biochem.Biophys.Res.Commun., 369, 2008
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2H31
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![BU of 2h31 by Molmil](/molmil-images/mine/2h31) | Crystal structure of human PAICS, a bifunctional carboxylase and synthetase in purine biosynthesis | Descriptor: | CARBON DIOXIDE, Multifunctional protein ADE2 | Authors: | Li, S.-X, Tong, Y.-P, Xie, X.-C, Li, S.-G, Bi, R.-C. | Deposit date: | 2006-05-21 | Release date: | 2007-01-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis. J.Mol.Biol., 366, 2007
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2FPV
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![BU of 2fpv by Molmil](/molmil-images/mine/2fpv) | Dual binding mode of a novel series of DHODH inhibitors | Descriptor: | 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID, ACETATE ION, Dihydroorotate dehydrogenase, ... | Authors: | Baumgartner, R, Leban, J. | Deposit date: | 2006-01-17 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49, 2006
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2DOR
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![BU of 2dor by Molmil](/molmil-images/mine/2dor) | |
2E6D
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![BU of 2e6d by Molmil](/molmil-images/mine/2e6d) | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with fumarate | Descriptor: | COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... | Authors: | Inaoka, D.K, Shimizu, H, Sakamoto, K, Shiba, T, Kurisu, G, Nara, T, Aoki, T, Harada, S, Kita, K. | Deposit date: | 2006-12-26 | Release date: | 2008-01-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction Biochemistry, 47, 2008
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2FPT
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![BU of 2fpt by Molmil](/molmil-images/mine/2fpt) | Dual Binding Mode of a Novel Series of DHODH inhibitors | Descriptor: | 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID, ACETATE ION, Dihydroorotate dehydrogenase, ... | Authors: | Baumgartner, R, Walloschek, M, Kralik, M, Gotschlich, A, Tasler, S, Leban, J. | Deposit date: | 2006-01-17 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49, 2006
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1EP3
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![BU of 1ep3 by Molmil](/molmil-images/mine/1ep3) | CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B. DATA COLLECTED UNDER CRYOGENIC CONDITIONS. | Descriptor: | DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT), DIHYDROOROTATE DEHYDROGENASE B (PYRK SUBUNIT), FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Rowland, P, Norager, S, Jensen, K.F, Larsen, S. | Deposit date: | 2000-03-27 | Release date: | 2001-01-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster. Structure Fold.Des., 8, 2000
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1EP2
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![BU of 1ep2 by Molmil](/molmil-images/mine/1ep2) | CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B COMPLEXED WITH OROTATE | Descriptor: | DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT), DIHYDROOROTATE DEHYDROGENASE B (PYRK SUBUNIT), FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Rowland, P, Norager, S, Jensen, K.F, Larsen, S. | Deposit date: | 2000-03-27 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster. Structure Fold.Des., 8, 2000
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2FPY
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![BU of 2fpy by Molmil](/molmil-images/mine/2fpy) | Dual binding mode of a novel series of DHODH inhibitors | Descriptor: | 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID, ACETATE ION, Dihydroorotate dehydrogenase, ... | Authors: | Baumgartner, R, Leban, J. | Deposit date: | 2006-01-17 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49, 2006
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1EP1
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![BU of 1ep1 by Molmil](/molmil-images/mine/1ep1) | CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B | Descriptor: | DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT), DIHYDROOROTATE DEHYDROGENASE B (PYRK SUBUNIT), FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Rowland, P, Norager, S, Jensen, K.F, Larsen, S. | Deposit date: | 2000-03-27 | Release date: | 2001-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of dihydroorotate dehydrogenase B: electron transfer between two flavin groups bridged by an iron-sulphur cluster. Structure Fold.Des., 8, 2000
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2FQI
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![BU of 2fqi by Molmil](/molmil-images/mine/2fqi) | dual binding modes of a novel series of DHODH inhibitors | Descriptor: | 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID, ACETATE ION, Dihydroorotate dehydrogenase, ... | Authors: | Baumgartner, R, Leban, J. | Deposit date: | 2006-01-18 | Release date: | 2007-01-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49, 2006
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2JVF
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![BU of 2jvf by Molmil](/molmil-images/mine/2jvf) | Solution structure of M7, a computationally-designed artificial protein | Descriptor: | de novo protein M7 | Authors: | Stordeur, C, Dalluege, R, Birkenmeier, O, Wienk, H, Rudolph, R, Lange, C, Luecke, C. | Deposit date: | 2007-09-19 | Release date: | 2008-08-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The NMR solution structure of the artificial protein M7 matches the computationally designed model Proteins, 72, 2008
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6L0I
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![BU of 6l0i by Molmil](/molmil-images/mine/6l0i) | Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0F
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![BU of 6l0f by Molmil](/molmil-images/mine/6l0f) | Crystal structure of dihydroorotase in complex with 5-Aminouracil from Saccharomyces cerevisiae | Descriptor: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.26 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0K
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![BU of 6l0k by Molmil](/molmil-images/mine/6l0k) | Crystal structure of dihydroorotase in complex with malate at pH9 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0H
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![BU of 6l0h by Molmil](/molmil-images/mine/6l0h) | Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.054 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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