2H31
Crystal structure of human PAICS, a bifunctional carboxylase and synthetase in purine biosynthesis
Summary for 2H31
Entry DOI | 10.2210/pdb2h31/pdb |
Descriptor | Multifunctional protein ADE2, CARBON DIOXIDE (3 entities in total) |
Functional Keywords | alpha-beta-alpha, ligase, lyase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 47507.38 |
Authors | Li, S.-X.,Tong, Y.-P.,Xie, X.-C.,Li, S.-G.,Bi, R.-C. (deposition date: 2006-05-21, release date: 2007-01-30, Last modification date: 2011-07-13) |
Primary citation | Li, S.X.,Tong, Y.P.,Xie, X.C.,Wang, Q.H.,Zhou, H.N.,Han, Y.,Zhang, Z.Y.,Gao, W.,Li, S.G.,Zhang, X.C.,Bi, R.C. Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis. J.Mol.Biol., 366:1603-1614, 2007 Cited by PubMed: 17224163DOI: 10.1016/j.jmb.2006.12.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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