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2ESJ
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BU of 2esj by Molmil
Complex between Lividomycin A and the 16S-Rrna A Site
Descriptor: (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Authors:Westhof, E.
Deposit date:2005-10-26
Release date:2005-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding
Nucleic Acids Res., 33, 2005
5US2
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BU of 5us2 by Molmil
2-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
Descriptor: DNA (5'-D(*AP*(US3)P*GP*TP*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ...
Authors:Fang, Z, Yang, F, Huang, Z.
Deposit date:2017-02-13
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:2-Se-T-modified-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant
To Be Published
3L8U
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BU of 3l8u by Molmil
Crystal structure of SMU.1707c, a putative rRNA methyltransferase from streptococcus mutans UA159
Descriptor: Putative rRNA methylase
Authors:Gao, X.-Z, Wang, K.-T, Su, X.-D.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of SMU.1707c, a putative rRNA methyltransferase from streptococcus mutans UA159
To be published
2EVZ
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BU of 2evz by Molmil
Structure of RNA Binding Domains 3 and 4 of Polypyrimidine Tract Binding Protein
Descriptor: Polypyrimidine tract-binding protein 1
Authors:Allain, F.H, Auweter, S.D.
Deposit date:2005-11-01
Release date:2006-01-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the two most C-terminal RNA recognition motifs of PTB using segmental isotope labeling
Embo J., 25, 2006
2ZWV
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BU of 2zwv by Molmil
Crystal structure of Thermus thermophilus 16S rRNA methyltransferase RsmC (TTHA0533)
Descriptor: Probable ribosomal RNA small subunit methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wang, H, Kawazoe, M, Kaminishi, T, Tatsuguchi, A, Naoe, C, Terada, T, Shirouzu, M, Takemoto, C, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-12-18
Release date:2009-12-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Thermus thermophilus 16S rRNA methyltransferase RsmC (TTHA0533)
to be published
1WKW
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BU of 1wkw by Molmil
Crystal structure of the ternary complex of eIF4E-m7GpppA-4EBP1 peptide
Descriptor: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E binding protein 1, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
Authors:Tomoo, K, Matsushita, Y, Fujisaki, H, Shen, X, Miyagawa, H, Kitamura, K, Miura, K, Ishida, T.
Deposit date:2004-06-10
Release date:2005-06-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods
Biochim.Biophys.Acta, 1753, 2005
2ZUL
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BU of 2zul by Molmil
Crystal structure of Thermus thermophilus 16S rRNA methyltransferase RsmC (TTHA0533) in complex with cofactor S-adenosyl-L-Methionine
Descriptor: Probable ribosomal RNA small subunit methyltransferase, S-ADENOSYLMETHIONINE
Authors:Wang, H, Kawazoe, M, Tatsuguchi, A, Naoe, C, Takemoto, C, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-10-21
Release date:2009-10-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Thermus thermophilus 16S rRNA methyltransferase RsmC (TTHA0533) in complex with cofactor S-adenosyl-L-Methionine
To be Published
2QFD
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BU of 2qfd by Molmil
Crystal structure of the regulatory domain of human RIG-I with bound Hg
Descriptor: MERCURY (II) ION, Probable ATP-dependent RNA helicase DDX58
Authors:Cui, S, Lammens, A, Lammens, K, Hopfner, K.P.
Deposit date:2007-06-27
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
3HK2
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BU of 3hk2 by Molmil
Crystal structure of T. thermophilus Argonaute N478 mutant protein complexed with DNA guide strand and 19-nt RNA target strand
Descriptor: 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', 5'-R(*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', Argonaute, ...
Authors:Wang, Y, Li, H, Sheng, G, Patel, D.J.
Deposit date:2009-05-22
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes.
Nature, 461, 2009
2DGP
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BU of 2dgp by Molmil
Solution structure of the N-terminal RNA binding domain in Bruno-like 4 RNA-binding protein
Descriptor: Bruno-like 4, RNA binding protein
Authors:Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-15
Release date:2006-09-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal RNA binding domain in Bruno-like 4 RNA-binding protein
To be Published
1QHK
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BU of 1qhk by Molmil
N-TERMINAL DOMAIN OF SACCHAROMYCES CEREVISIAE RNASE HI REVEALS A FOLD WITH A RESEMBLANCE TO THE N-TERMINAL DOMAIN OF RIBOSOMAL PROTEIN L9
Descriptor: PROTEIN (RIBONUCLEASE HI)
Authors:Evans, S.P, Bycroft, M.
Deposit date:1999-05-17
Release date:1999-08-31
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR structure of the N-terminal domain of Saccharomyces cerevisiae RNase HI reveals a fold with a strong resemblance to the N-terminal domain of ribosomal protein L9.
J.Mol.Biol., 291, 1999
1CMY
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BU of 1cmy by Molmil
THE MUTATION BETA99 ASP-TYR STABILIZES Y-A NEW, COMPOSITE QUATERNARY STATE OF HUMAN HEMOGLOBIN
Descriptor: HEMOGLOBIN YPSILANTI (CARBONMONOXY) (ALPHA CHAIN), HEMOGLOBIN YPSILANTI (CARBONMONOXY) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE
Authors:Smith, F.R, Lattman, E.E, Carter Junior, C.W.
Deposit date:1992-09-18
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:The mutation beta 99 Asp-Tyr stabilizes Y--a new, composite quaternary state of human hemoglobin.
Proteins, 10, 1991
6F9W
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BU of 6f9w by Molmil
Crystal structure of the LSM domain of LSM14 in complex with a C-terminal peptide of 4E-T
Descriptor: Eukaryotic translation initiation factor 4E transporter, Protein LSM14 homolog A
Authors:Brandmann, T, Jinek, M.
Deposit date:2017-12-15
Release date:2018-03-21
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.
EMBO J., 37, 2018
4GZZ
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BU of 4gzz by Molmil
Crystal structures of bacterial RNA Polymerase paused elongation complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A.
Deposit date:2012-09-06
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.2927 Å)
Cite:Structural basis of transcriptional pausing in bacteria.
Cell(Cambridge,Mass.), 152, 2013
4E76
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BU of 4e76 by Molmil
Apo crystal structure of HCV NS5B genotype 2A JFH-1 isolate with beta hairpin loop deletion
Descriptor: 1,2-ETHANEDIOL, RNA-directed RNA polymerase, SULFATE ION
Authors:Edwards, T.E, Mosley, R.T.
Deposit date:2012-03-16
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of hepatitis C virus polymerase in complex with primer-template RNA.
J.Virol., 86, 2012
4NH5
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BU of 4nh5 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 14-mer siRNA having 5'-pUU and UU-3' ends (2.55 Angstrom resolution)
Descriptor: 5'-R(P*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Tian, Y, Simanshu, D.K, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
6BJX
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BU of 6bjx by Molmil
Group I self-splicing intron P4-P6 domain mutant U131A (with isopropanol soaking)
Descriptor: Group I self-splicing intron P4-P6 domain, MAGNESIUM ION
Authors:Shoffner, G.M.
Deposit date:2017-11-07
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:In Crystallo Selection to Establish New RNA Crystal Contacts.
Structure, 26, 2018
4NGG
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BU of 4ngg by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 13-mer siRNA having 5'-A and UU-3' ends (2.6 Angstrom resolution)
Descriptor: 5'-R(*AP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer, PHOSPHATE ION
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
2HH3
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BU of 2hh3 by Molmil
Solution structure of the third KH domain of KSRP
Descriptor: KH-type splicing regulatory protein
Authors:Garcia-Mayoral, M.F.
Deposit date:2006-06-27
Release date:2007-05-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
Structure, 15, 2007
4NGC
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BU of 4ngc by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having UA-3' ends (2.1 Angstrom resolution)
Descriptor: 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*A)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH6
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BU of 4nh6 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 15-mer siRNA having 5'-pUUU and UU-3' ends (2.55 Angstrom resolution)
Descriptor: 5'-R(P*UP*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
7A8P
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BU of 7a8p by Molmil
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.
Descriptor: (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid, DNA-directed RNA polymerase, mitochondrial
Authors:Hillen, H.S, Bonekamp, N, Peter, B, Felser, A, Bergbrede, T, Choidas, A, Horn, M, Unger, A, di Lucrezia, R, Atanassov, I, Li, X, Koch, U, Menninger, S, Boros, J, Habenberger, P, Giavalisco, P, Cramer, P, Denzel, M, Nussbaumer, P, Klebl, B, Falkenberg, M, Gustafsson, C.M, Larsson, N.G.
Deposit date:2020-08-30
Release date:2020-12-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Small-molecule inhibitors of human mitochondrial DNA transcription.
Nature, 588, 2020
2CLX
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BU of 2clx by Molmil
4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects
Descriptor: 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, CELL DIVISION PROTEIN KINASE 2
Authors:Krystof, V, Cankar, P, Frysova, I, Slouka, J, Kontopidis, G, Dzubak, P, Hajduch, M, Deazevedo, W.F, Paprskarova, M, Orsag, M, Rolcik, J, Latr, A, Fischer, P.M, Strnad, M.
Deposit date:2006-05-02
Release date:2006-11-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:4-Arylazo-3,5-Diamino-1H-Pyrazole Cdk Inhibitors: Sar Study, Crystal Structure in Complex with Cdk2, Selectivity, and Cellular Effects
J.Med.Chem., 49, 2006
2HXY
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BU of 2hxy by Molmil
Crystal structure of human apo-eIF4AIII
Descriptor: Probable ATP-dependent RNA helicase DDX48
Authors:Johansen, J.S, Andersen, G.R.
Deposit date:2006-08-04
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
7ABL
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BU of 7abl by Molmil
HBV pgRNA T=4 NCP icosahedral symmetry
Descriptor: Capsid protein
Authors:Patel, N, Clark, S, Weis, E.U, Mata, C.P, Bohon, J, Farquhar, E, Ranson, N.A, Twarock, R, Stockley, P.G.
Deposit date:2020-09-07
Release date:2021-10-27
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:In vitro functional analysis of gRNA sites regulating assembly of hepatitis B virus.
Commun Biol, 4, 2021

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數據於2024-10-16公開中

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