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8FTI
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BU of 8fti by Molmil
Cryo-EM structure of the Cas13bt3-crRNA-target RNA ternary complex in activated state
Descriptor: Integrase, crRNA-linker-target hairpin RNA
Authors:Gao, Y, Deng, X.
Deposit date:2023-01-12
Release date:2023-09-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the activation of a compact CRISPR-Cas13 nuclease.
Nat Commun, 14, 2023
8GRI
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BU of 8gri by Molmil
Orf1-E312A-glycine-glycylthricin
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase, ...
Authors:Wang, Y.L, Li, T.L.
Deposit date:2022-09-01
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.365 Å)
Cite:N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
8GMO
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BU of 8gmo by Molmil
Bacteriophage T4 capsid shell containing 9DE insertions into the gp23* major capsid protein subunits
Descriptor: Mature capsid vertex protein, Mature major capsid protein
Authors:Fokine, A, Rao, V.B.
Deposit date:2023-03-26
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Design of bacteriophage T4-based artificial viral vectors for human genome remodeling.
Nat Commun, 14, 2023
8GHZ
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BU of 8ghz by Molmil
Cryo-EM structure of fish immunogloblin M-Fc
Descriptor: Teleost immunoglobulin M protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Lyu, M, Stadtmueller, B.M, Malyutin, A.G.
Deposit date:2023-03-13
Release date:2023-11-08
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function.
Nat Commun, 14, 2023
8HPJ
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BU of 8hpj by Molmil
Crystal structure of the bacterial oxalate transporter OxlT in a ligand-free outward-facing form
Descriptor: Fv fragment Heavy chain, Fv fragment Light chain, Oxalate:formate antiporter
Authors:Shimamura, T, Hirai, T, Yamashita, A.
Deposit date:2022-12-12
Release date:2023-02-15
Last modified:2023-04-12
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota.
Nat Commun, 14, 2023
6VY1
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BU of 6vy1 by Molmil
Cryo-EM structure of filamentous PFD from Methanocaldococcus jannaschii
Descriptor: Prefoldin subunit alpha 2
Authors:Wang, F, Chen, Y.X, Ing, N.L, Hochbaum, A.I, Clark, D.S, Glover, D.J, Egelman, E.H.
Deposit date:2020-02-25
Release date:2020-05-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural Determination of a Filamentous Chaperone to Fabricate Electronically Conductive Metalloprotein Nanowires.
Acs Nano, 14, 2020
4TUJ
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BU of 4tuj by Molmil
Crystal structure of monoclonal antibody against neuroblastoma associated antigen.
Descriptor: Heavy chain of monoclonal antibody against neuroblastoma associated antigen, Light chain of monoclonal antibody against neuroblastoma associated antigen, peptide1
Authors:Grudnik, P, Golik, P, Horwacik, I, Zdzalik, M, Rokita, H, Dubin, G.
Deposit date:2014-06-24
Release date:2015-07-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis of GD2 Ganglioside and Mimetic Peptide Recognition by 14G2a Antibody.
Mol.Cell Proteomics, 14, 2015
8HEY
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BU of 8hey by Molmil
One CVSC-binding penton vertex in HCMV B-capsid
Descriptor: Capsid vertex component 1, Capsid vertex component 2, Major capsid protein, ...
Authors:Li, Z, Yu, X.
Deposit date:2022-11-09
Release date:2023-11-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus.
Nat Commun, 14, 2023
8ENV
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BU of 8env by Molmil
In situ cryo-EM structure of Pseudomonas phage E217 tail baseplate in C6 map
Descriptor: Baseplate_J domain-containing protein gp44, Ripcord gp36, Sheath initiator gp34, ...
Authors:Li, F, Cingolani, G, Hou, C.
Deposit date:2022-09-30
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.
Nat Commun, 14, 2023
8HEX
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BU of 8hex by Molmil
C5 portal vertex in HCMV B-capsid
Descriptor: Capsid vertex component 1, Capsid vertex component 2, Major capsid protein, ...
Authors:Li, Z, Yu, X.
Deposit date:2022-11-08
Release date:2023-11-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus.
Nat Commun, 14, 2023
1U57
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BU of 1u57 by Molmil
NMR structure of the (345-392)Gag sequence from HIV-1
Descriptor: Gag polyprotein
Authors:Morellet, N, Druillennec, S, Lenoir, C, Bouaziz, S, Roques, B.P.
Deposit date:2004-07-27
Release date:2005-02-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Helical structure determined by NMR of the HIV-1 (345-392)Gag sequence, surrounding p2: Implications for particle assembly and RNA packaging
Protein Sci., 14, 2005
8I23
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BU of 8i23 by Molmil
Clostridium thermocellum RNA polymerase transcription open complex with SigI1 and its promoter
Descriptor: DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P.
Deposit date:2023-01-13
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structure of the transcription open complex of distinct sigma I factors.
Nat Commun, 14, 2023
8I24
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BU of 8i24 by Molmil
Clostridium thermocellum RNA polymerase transcription open complex with SigI6 and its promoter
Descriptor: DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P.
Deposit date:2023-01-13
Release date:2023-10-11
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structure of the transcription open complex of distinct sigma I factors.
Nat Commun, 14, 2023
8I8B
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BU of 8i8b by Molmil
Outer shell and inner layer structures of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
Descriptor: 38K, AcOrf-109 peptide, Early 49 Daa protein, ...
Authors:Jia, X, Gao, Y, Zhang, Q.
Deposit date:2023-02-03
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (4.31 Å)
Cite:Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
5EXH
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BU of 5exh by Molmil
Crystal structure of mTET3-CXXC domain in complex with 5-carboxylcytosine DNA at 1.3 Angstroms resolution.
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*(1CC)P*GP*GP*AP*TP*TP*C)-3'), Methylcytosine dioxygenase TET3, ZINC ION
Authors:Song, J.
Deposit date:2015-11-23
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration.
Cell Rep, 14, 2016
5J3X
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BU of 5j3x by Molmil
Structure of c-CBL Y371F
Descriptor: CALCIUM ION, E3 ubiquitin-protein ligase CBL, ZINC ION
Authors:Huang, D.T, Buetow, L, Dou, H.
Deposit date:2016-03-31
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.822 Å)
Cite:Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.
Bmc Biol., 14, 2016
5K7Y
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BU of 5k7y by Molmil
Crystal structure of enzyme in purine metabolism
Descriptor: Cytosolic purine 5'-nucleotidase, GLYCEROL
Authors:Skerlova, J, Hnizda, A, Pachl, P, Rezacova, P.
Deposit date:2016-05-27
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
1WAU
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BU of 1wau by Molmil
Structure of KDPG Aldolase E45N mutant
Descriptor: KHG/KDPG ALDOLASE, SULFATE ION
Authors:Merkel, A.B, Naismith, J.H.
Deposit date:2004-10-28
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
8K71
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BU of 8k71 by Molmil
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((2-((naphthalen-2-ylmethyl)sulfonyl)acetyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Descriptor: 2-[(2~{Z})-2-[2-(naphthalen-2-ylmethylsulfonyl)ethanoylimino]-3-oxidanyl-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
Authors:Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J.
Deposit date:2023-07-26
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha.
Chem Sci, 14, 2023
8K72
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BU of 8k72 by Molmil
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((3-(phenylsulfonamido)propanoyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Descriptor: 2-[(2~{Z})-3-oxidanyl-2-[3-(phenylsulfonylamino)propanoylimino]-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
Authors:Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J.
Deposit date:2023-07-26
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha.
Chem Sci, 14, 2023
8K73
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BU of 8k73 by Molmil
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((1-(phenylsulfonyl)pyrrolidine-3-carbonyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Descriptor: 2-[(2~{Z})-3-oxidanyl-2-[(3~{R})-1-(phenylsulfonyl)pyrrolidin-3-yl]carbonylimino-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
Authors:Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J.
Deposit date:2023-07-26
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha.
Chem Sci, 14, 2023
1WA3
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BU of 1wa3 by Molmil
Mechanism of the Class I KDPG aldolase
Descriptor: 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE, PYRUVIC ACID, SULFATE ION
Authors:Fullerton, S.W.B, Griffiths, J.S, Merkel, A.B, Wymer, N.J, Hutchins, M.J, Fierke, C.A, Toone, E.J, Naismith, J.H.
Deposit date:2004-10-22
Release date:2005-01-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
1WBH
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BU of 1wbh by Molmil
Crystal structure of the E45N mutant from KDPG aldolase from Escherichia coli
Descriptor: KHG/KDPG ALDOLASE, PHOSPHATE ION
Authors:Fullerton, S.W.B, Merkel, A.B, Naismith, J.H.
Deposit date:2004-11-01
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
8JMW
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BU of 8jmw by Molmil
Fibril form of serine peptidase Vpr
Descriptor: S8 family serine peptidase
Authors:Cao, Q, Cheng, Y.
Deposit date:2023-06-05
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EM.
Nat Commun, 14, 2023
8P5U
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BU of 8p5u by Molmil
Single particle cryo-EM structure of homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum with Coenzyme A bound to the E2o domain
Descriptor: 2-oxoglutarate dehydrogenase E1/E2 component, ACETYL COENZYME *A, COENZYME A, ...
Authors:Yang, L, Mechaly, A.M, Bellinzoni, M.
Deposit date:2023-05-24
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.17 Å)
Cite:High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023

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數據於2024-09-11公開中

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