1SE0
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![BU of 1se0 by Molmil](/molmil-images/mine/1se0) | Crystal structure of DIAP1 BIR1 bound to a Grim peptide | Descriptor: | Apoptosis 1 inhibitor, Cell death protein Grim, ZINC ION | Authors: | Yan, N, Wu, J.W, Shi, Y. | Deposit date: | 2004-02-15 | Release date: | 2004-04-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim. Nat.Struct.Mol.Biol., 11, 2004
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1S5I
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![BU of 1s5i by Molmil](/molmil-images/mine/1s5i) | Fab (LNKB-2) of monoclonal antibody to Human Interleukin-2, crystal structure | Descriptor: | Fab-fragment of monoclonal antibody | Authors: | Pletnev, V.Z, Goryacheva, E.A, Tsygannik, I.N, Nesmeyanov, V.A, Pletnev, S.V, Pangborn, W, Duax, W. | Deposit date: | 2004-01-21 | Release date: | 2004-05-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | [A new crystal form of the Fab fragment of a monoclonal antibody to human interleukin-2: the three-dimensional structure at 2.7 A resolution]. Bioorg. Khim., 30
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5U2E
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3KJP
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![BU of 3kjp by Molmil](/molmil-images/mine/3kjp) | Crystal Structure of hPOT1V2-GGTTAGGGTTAG | Descriptor: | 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1 | Authors: | Nandakumar, J, Cech, T.R, Podell, E.R. | Deposit date: | 2009-11-03 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc.Natl.Acad.Sci.USA, 107, 2010
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4Y2G
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1SH6
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4XUS
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![BU of 4xus by Molmil](/molmil-images/mine/4xus) | Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming dTTP | Descriptor: | 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*A)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... | Authors: | Burak, M.J, Guja, K.E, Garcia-Diaz, M. | Deposit date: | 2015-01-26 | Release date: | 2016-02-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda. Nucleic Acids Res., 43, 2015
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5JH5
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![BU of 5jh5 by Molmil](/molmil-images/mine/5jh5) | Structural Basis for the Hierarchical Assembly of the Core of PRC1.1 | Descriptor: | BCL-6 corepressor-like protein 1, Lysine-specific demethylase 2B, Polycomb group RING finger protein 1, ... | Authors: | Wong, S.J, Taylor, A.B, Hart, P.J, Kim, C.A. | Deposit date: | 2016-04-20 | Release date: | 2016-09-14 | Last modified: | 2016-10-19 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1. Structure, 24, 2016
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5TWV
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![BU of 5twv by Molmil](/molmil-images/mine/5twv) | Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11 | Authors: | Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L. | Deposit date: | 2016-11-14 | Release date: | 2017-01-25 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating. Elife, 6, 2017
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5J2B
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3KEH
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![BU of 3keh by Molmil](/molmil-images/mine/3keh) | Crystal Structure of N370S Glucocerebrosidase mutant at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wei, R.R, Boucher, S, Pan, C.Q, Edmunds, T. | Deposit date: | 2009-10-26 | Release date: | 2010-10-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Glucocerebrosidase Containing the N370S mutation: Implication on Chaperon Therapy To be Published
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5J2H
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5J2R
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![BU of 5j2r by Molmil](/molmil-images/mine/5j2r) | Solution structure of Ras Binding Domain (RBD) of B-Raf | Descriptor: | N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine, Serine/threonine-protein kinase B-raf | Authors: | Dutta, K, Vasquez-Del Carpio, R, Aggarwal, A.K, Reddy, E.P. | Deposit date: | 2016-03-29 | Release date: | 2016-05-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling. Cell, 165, 2016
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5JJA
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![BU of 5jja by Molmil](/molmil-images/mine/5jja) | Crystal structure of a PP2A B56gamma/BubR1 complex | Descriptor: | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | Authors: | Wang, Z, Wang, J, Rao, Z, Xu, W. | Deposit date: | 2016-04-22 | Release date: | 2016-07-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization. Protein Cell, 7, 2016
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4Y17
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![BU of 4y17 by Molmil](/molmil-images/mine/4y17) | SdiA in complex with 3-oxo-C8-homoserine lactone | Descriptor: | 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, Transcriptional regulator of ftsQAZ gene cluster | Authors: | Nguyen, N.X, Nguyen, Y, Sperandio, V, Jiang, Y. | Deposit date: | 2015-02-06 | Release date: | 2015-04-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural and Mechanistic Roles of Novel Chemical Ligands on the SdiA Quorum-Sensing Transcription Regulator. Mbio, 6, 2015
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5U4Y
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![BU of 5u4y by Molmil](/molmil-images/mine/5u4y) | IgG Fc bound to 3 helix of the B-domain from Protein A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 fc, Immunoglobulin G-binding protein A, ... | Authors: | Ultsch, M.H, Eigenbrot, C. | Deposit date: | 2016-12-06 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4994 Å) | Cite: | 3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix. Protein Eng. Des. Sel., 30, 2017
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3KGQ
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![BU of 3kgq by Molmil](/molmil-images/mine/3kgq) | Carboxypeptidase A liganded to an organic small-molecule: conformational changes | Descriptor: | ACETONE, CITRIC ACID, Carboxypeptidase A1, ... | Authors: | Fernandez, D, Boix, E, Pallares, I, Aviles, F.X, Vendrell, J. | Deposit date: | 2009-10-29 | Release date: | 2010-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A Enzyme Res, 2011, 2011
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5U6G
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5IXF
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![BU of 5ixf by Molmil](/molmil-images/mine/5ixf) | Solution structure of the STAM2 SH3 with AMSH derived peptide complex | Descriptor: | STAM-binding protein, Signal transducing adapter molecule 2 | Authors: | Hologne, M, Cantrelle, F.X, Trivelli, X, Walker, O. | Deposit date: | 2016-03-23 | Release date: | 2016-12-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin. J.Mol.Biol., 428, 2016
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3KMR
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![BU of 3kmr by Molmil](/molmil-images/mine/3kmr) | Crystal structure of RARalpha ligand binding domain in complex with an agonist ligand (Am580) and a coactivator fragment | Descriptor: | 4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid, Nuclear receptor coactivator 1, Retinoic acid receptor alpha | Authors: | Bourguet, W, Teyssier, C. | Deposit date: | 2009-11-11 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor. Nat.Struct.Mol.Biol., 17, 2010
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3KFA
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5JQS
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3KYT
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3KZF
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![BU of 3kzf by Molmil](/molmil-images/mine/3kzf) | Structure of Giardia Carbamate Kinase | Descriptor: | Carbamate kinase, GLYCEROL | Authors: | Galkin, A, Herzberg, O. | Deposit date: | 2009-12-08 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray structure and characterization of carbamate kinase from the human parasite Giardia lamblia. Acta Crystallogr.,Sect.F, 66, 2010
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5JS6
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![BU of 5js6 by Molmil](/molmil-images/mine/5js6) | Crystal structure of 17beta-hydroxysteroid dehydrogenase 14 T205 variant in complex with NAD. | Descriptor: | 17-beta-hydroxysteroid dehydrogenase 14, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. | Deposit date: | 2016-05-07 | Release date: | 2016-07-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor. J.Med.Chem., 59, 2016
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