5J2R
Solution structure of Ras Binding Domain (RBD) of B-Raf
Summary for 5J2R
| Entry DOI | 10.2210/pdb5j2r/pdb |
| Related | 5J17 5J18 |
| NMR Information | BMRB: 30050 |
| Descriptor | Serine/threonine-protein kinase B-raf, N-[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine (2 entities in total) |
| Functional Keywords | mapk, pi3k, protein binding |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus : P15056 |
| Total number of polymer chains | 1 |
| Total formula weight | 10762.57 |
| Authors | Dutta, K.,Vasquez-Del Carpio, R.,Aggarwal, A.K.,Reddy, E.P. (deposition date: 2016-03-29, release date: 2016-05-04) |
| Primary citation | Athuluri-Divakar, S.K.,Vasquez-Del Carpio, R.,Dutta, K.,Baker, S.J.,Cosenza, S.C.,Basu, I.,Gupta, Y.K.,Reddy, M.V.,Ueno, L.,Hart, J.R.,Vogt, P.K.,Mulholland, D.,Guha, C.,Aggarwal, A.K.,Reddy, E.P. A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling. Cell, 165:643-655, 2016 Cited by PubMed: 27104980DOI: 10.1016/j.cell.2016.03.045 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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