2RH3
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![BU of 2rh3 by Molmil](/molmil-images/mine/2rh3) | Crystal structure of plasmid pTiC58 VirC2 | Descriptor: | Protein virC2 | Authors: | Lu, J, Glover, J.N.M. | Deposit date: | 2007-10-05 | Release date: | 2008-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Agrobacterium tumefaciens VirC2 enhances T-DNA transfer and virulence through its C-terminal ribbon-helix-helix DNA-binding fold Proc.Natl.Acad.Sci.USA, 106, 2009
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1BI2
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![BU of 1bi2 by Molmil](/molmil-images/mine/1bi2) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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6VH6
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![BU of 6vh6 by Molmil](/molmil-images/mine/6vh6) | |
6TD4
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![BU of 6td4 by Molmil](/molmil-images/mine/6td4) | IRF4 DNA-binding domain surface entropy mutant apo structure | Descriptor: | CHLORIDE ION, Interferon regulatory factor 4 | Authors: | Tucker, J.A, Martin, M.P, Wang, L.Z, Jennings, C, Heath, R. | Deposit date: | 2019-11-07 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Cancer-associated mutations in the IRF4 DNA-binding domain confer no disadvantage in DNA-binding affinity and may increase transcriptional activity To Be Published
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7TIL
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![BU of 7til by Molmil](/molmil-images/mine/7til) | CryoEM structure of JetD from Pseudomonas aeruginosa | Descriptor: | JetD | Authors: | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | Deposit date: | 2022-01-13 | Release date: | 2022-10-05 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA. Mol.Cell, 82, 2022
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5FGP
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![BU of 5fgp by Molmil](/molmil-images/mine/5fgp) | Crystal structure of D. melanogaster Pur-alpha repeat I-II in complex with DNA. | Descriptor: | CG1507-PB, isoform B, CHLORIDE ION, ... | Authors: | Weber, J, Janowski, R, Niessing, D. | Deposit date: | 2015-12-21 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha. Elife, 5, 2016
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4IRH
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![BU of 4irh by Molmil](/molmil-images/mine/4irh) | Auto-inhibited ERG Ets domain | Descriptor: | Transcriptional regulator ERG | Authors: | Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. | Deposit date: | 2013-01-14 | Release date: | 2013-07-31 | Last modified: | 2013-08-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
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5G5S
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![BU of 5g5s by Molmil](/molmil-images/mine/5g5s) | Structure of the Argonaute protein from Methanocaldcoccus janaschii | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ARGONAUTE, MAGNESIUM ION | Authors: | Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S. | Deposit date: | 2016-06-03 | Release date: | 2017-02-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein. Nat Microbiol, 2, 2017
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1BI0
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![BU of 1bi0 by Molmil](/molmil-images/mine/1bi0) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Hol, W.G. | Deposit date: | 1998-06-21 | Release date: | 1999-07-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1BI1
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![BU of 1bi1 by Molmil](/molmil-images/mine/1bi1) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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1BI3
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![BU of 1bi3 by Molmil](/molmil-images/mine/1bi3) | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | Authors: | Pohl, E, Hol, W.G.J. | Deposit date: | 1998-06-21 | Release date: | 1999-06-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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2M8E
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![BU of 2m8e by Molmil](/molmil-images/mine/2m8e) | NMR structure of the PAI subdomain of Sleeping Beauty transposase | Descriptor: | SLEEPING BEAUTY TRANSPOSASE | Authors: | Eubanks, C, Schreifels, J, Aronovich, E, Carlson, D, Hacjkett, P, Nesmelova, I. | Deposit date: | 2013-05-17 | Release date: | 2013-12-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structural analysis of Sleeping Beauty transposase binding to DNA. Protein Sci., 23, 2014
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7SFG
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![BU of 7sfg by Molmil](/molmil-images/mine/7sfg) | Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Cofactor SAM | Descriptor: | 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 1, DNA Strand 1, ... | Authors: | Horton, J.R, Pathuri, S, Cheng, X. | Deposit date: | 2021-10-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
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5YBX
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![BU of 5ybx by Molmil](/molmil-images/mine/5ybx) | Crystal structure of the N-terminal domain of Bqt4 in S.pombe | Descriptor: | Bouquet formation protein 4 | Authors: | Hu, C, Chen, Y. | Deposit date: | 2017-09-05 | Release date: | 2018-09-19 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | The Inner Nuclear Membrane Protein Bqt4 in Fission Yeast Contains a DNA-Binding Domain Essential for Telomere Association with the Nuclear Envelope. Structure, 27, 2019
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2M9M
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![BU of 2m9m by Molmil](/molmil-images/mine/2m9m) | Solution Structure of ERCC4 domain of human FAAP24 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | Deposit date: | 2013-06-18 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
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1GJI
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![BU of 1gji by Molmil](/molmil-images/mine/1gji) | Crystal structure of c-Rel bound to DNA | Descriptor: | C-REL PROTO-ONCOGENE PROTEIN, IL-2 CD28RE DNA | Authors: | Huang, D.B, Chen, Y.Q, Ruetsche, M, Phelps, C.B, Ghosh, G. | Deposit date: | 2001-05-30 | Release date: | 2002-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2. Structure, 9, 2001
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2M9N
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![BU of 2m9n by Molmil](/molmil-images/mine/2m9n) | Solution Structure of (HhH)2 domain of human FAAP24 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | Deposit date: | 2013-06-18 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
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2ODN
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![BU of 2odn by Molmil](/molmil-images/mine/2odn) | MSRECA-dATP complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA | Authors: | Krishna, R, Rajan Prabu, J, Manjunath, G.P, Datta, S, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2006-12-24 | Release date: | 2007-06-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA J.Mol.Biol., 367, 2007
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2FBK
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![BU of 2fbk by Molmil](/molmil-images/mine/2fbk) | The Crystal Structure of HucR from Deinococcus radiodurans | Descriptor: | CHLORIDE ION, transcriptional regulator, MarR family | Authors: | Bordelon, T, Wilkinson, S.P, Grove, A, Newcomer, M.E. | Deposit date: | 2005-12-09 | Release date: | 2006-07-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of the Transcriptional Regulator HucR from Deinococcus radiodurans Reveals a Repressor Preconfigured for DNA Binding. J.Mol.Biol., 360, 2006
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6LMS
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7SFD
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![BU of 7sfd by Molmil](/molmil-images/mine/7sfd) | Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3543105A | Descriptor: | (2S)-2-({3,5-dicyano-4-ethyl-6-[4-(2-hydroxyethyl)-1,4-diazepan-1-yl]pyridin-2-yl}sulfanyl)-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... | Authors: | Horton, J.R, Pathuri, S, Cheng, X. | Deposit date: | 2021-10-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
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7SFF
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![BU of 7sff by Molmil](/molmil-images/mine/7sff) | Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3852279B | Descriptor: | (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl}-2-[4-(trifluoromethyl)phenyl]acetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... | Authors: | Horton, J.R, Pathuri, S, Cheng, X. | Deposit date: | 2021-10-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
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7SFC
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![BU of 7sfc by Molmil](/molmil-images/mine/7sfc) | Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3735967A | Descriptor: | 1,2-ETHANEDIOL, DNA (12-MER), DNA (cytosine-5)-methyltransferase 1, ... | Authors: | Horton, J.R, Pathuri, S, Cheng, X. | Deposit date: | 2021-10-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
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7SFE
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![BU of 7sfe by Molmil](/molmil-images/mine/7sfe) | Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3830334A | Descriptor: | (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]amino}-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (12-MER), ... | Authors: | Horton, J.R, Pathuri, S, Cheng, X. | Deposit date: | 2021-10-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors. Structure, 30, 2022
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5ILS
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![BU of 5ils by Molmil](/molmil-images/mine/5ils) | Autoinhibited ETV1 | Descriptor: | ETS translocation variant 1 | Authors: | Whitby, F.G, Currie, S.L. | Deposit date: | 2016-03-04 | Release date: | 2017-02-22 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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