3UU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uu1 by Molmil](/molmil-images/mine/3uu1) | Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS142) | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-3,5-dimethylbenzoic acid, Anthranilate phosphoribosyltransferase, ... | Authors: | Castell, A, Short, F.L, Lott, J.S. | Deposit date: | 2011-11-27 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
|
|
4GIU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4giu by Molmil](/molmil-images/mine/4giu) | Bianthranilate-like analogue bound in inner site of anthranilate phosphoribosyltransferase (AnPRT; trpD). | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-[(2-carboxy-5-methylphenyl)amino]-3-methylbenzoic acid, Anthranilate phosphoribosyltransferase, ... | Authors: | Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2012-08-09 | Release date: | 2013-08-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.667 Å) | Cite: | Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis. Chembiochem, 15, 2014
|
|
1O17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o17 by Molmil](/molmil-images/mine/1o17) | |
2GVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gvq by Molmil](/molmil-images/mine/2gvq) | Anthranilate phosphoribosyl-transferase (TRPD) from S. solfataricus in complex with anthranilate | Descriptor: | 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase | Authors: | Marino, M, Deuss, M, Sterner, R, Mayans, O. | Deposit date: | 2006-05-03 | Release date: | 2006-05-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. J.Biol.Chem., 281, 2006
|
|
1B82
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b82 by Molmil](/molmil-images/mine/1b82) | PRISTINE RECOMB. LIGNIN PEROXIDASE H8 | Descriptor: | CALCIUM ION, PROTEIN (LIGNIN PEROXIDASE), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Blodig, W, Doyle, W.A, Smith, A.T, Piontek, K. | Deposit date: | 1999-02-04 | Release date: | 1999-02-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of pristine and oxidatively processed lignin peroxidase expressed in Escherichia coli and of the W171F variant that eliminates the redox active tryptophan 171. Implications for the reaction mechanism. J.Mol.Biol., 305, 2001
|
|
2KJ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kj4 by Molmil](/molmil-images/mine/2kj4) | Solution structure of the complex of VEK-30 and plasminogen kringle 2 | Descriptor: | VEK-30, plasminogen | Authors: | Wang, M, Zajicek, J, Prorok, M, Castellin, F.J. | Deposit date: | 2009-05-21 | Release date: | 2009-10-20 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the complex of VEK-30 and plasminogen kringle 2. J.Struct.Biol., 169, 2010
|
|
4QKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qks by Molmil](/molmil-images/mine/4qks) | Crystal Structure of 6xTrp/PV2: de novo designed beta-trefoil architecture with symmetric primary structure (L22W/L44W/L64W/L85W/L108W/L132W his Primitive Version 2) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DE NOVO PROTEIN 6XTRP/PV2, SULFATE ION | Authors: | Longo, L.M, Tenorio, C.A, Blaber, M. | Deposit date: | 2014-06-09 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding. Protein Sci., 24, 2015
|
|
3WO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wo1 by Molmil](/molmil-images/mine/3wo1) | Crystal structure of Trp332Ala mutant YwfE, an L-amino acid ligase, with bound ADP-Mg-Ala | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALANINE, Alanine-anticapsin ligase BacD, ... | Authors: | Tsuda, T, Kojima, S. | Deposit date: | 2013-12-19 | Release date: | 2014-05-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Single Mutation Alters the Substrate Specificity of l-Amino Acid Ligase Biochemistry, 53, 2014
|
|
1I5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i5k by Molmil](/molmil-images/mine/1i5k) | STRUCTURE AND BINDING DETERMINANTS OF THE RECOMBINANT KRINGLE-2 DOMAIN OF HUMAN PLASMINOGEN TO AN INTERNAL PEPTIDE FROM A GROUP A STREPTOCOCCAL SURFACE PROTEIN | Descriptor: | M PROTEIN, PLASMINOGEN | Authors: | Rios-Steiner, J.L, Schenone, M, Mochalkin, I, Tulinsky, A, Castellino, F.J. | Deposit date: | 2001-02-27 | Release date: | 2001-08-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein. J.Mol.Biol., 308, 2001
|
|
4KPR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kpr by Molmil](/molmil-images/mine/4kpr) | Tetrameric form of rat selenoprotein thioredoxin reductase 1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, SULFITE ION, ... | Authors: | Lindqvist, Y, Sandalova, T, Xu, J, Arner, E. | Deposit date: | 2013-05-14 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Trp114 residue of thioredoxin reductase 1 is an electron relay sensor for oxidative stress To be Published, 2013
|
|
4O98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o98 by Molmil](/molmil-images/mine/4o98) | Crystal structure of Pseudomonas oleovorans PoOPH mutant H250I/I263W | Descriptor: | ZINC ION, organophosphorus hydrolase | Authors: | Luo, X.J, Kong, X.D, Zhao, J, Chen, Q, Zhou, J.H, Xu, J.H. | Deposit date: | 2014-01-02 | Release date: | 2014-12-03 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp Biotechnol.Bioeng., 111, 2014
|
|
5Z05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z05 by Molmil](/molmil-images/mine/5z05) | Crystal structure of signalling protein from buffalo (SPB-40) with an acetone induced conformation of Trp78 at 1.49 A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ... | Authors: | Singh, P.K, Chaudhary, A, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2017-12-18 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | A glycoprotein from mammary gland secreted during involution promotes apoptosis: Structural and biological studies Arch. Biochem. Biophys., 644, 2018
|
|
5Z4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z4w by Molmil](/molmil-images/mine/5z4w) | Crystal structure of signalling protein from buffalo (SPB-40) with an altered conformation of Trp78 at 1.79 A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, ... | Authors: | Singh, P.K, Chaudhary, A, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2018-01-15 | Release date: | 2018-02-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | A glycoprotein from mammary gland secreted during involution promotes apoptosis: Structural and biological studies. Arch. Biochem. Biophys., 644, 2018
|
|
1F1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f1w by Molmil](/molmil-images/mine/1f1w) | SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE | Authors: | Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. | Deposit date: | 2000-05-20 | Release date: | 2000-07-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for specificity switching of the Src SH2 domain. Mol.Cell, 5, 2000
|
|
1F2F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f2f by Molmil](/molmil-images/mine/1f2f) | SRC SH2 THREF1TRP MUTANT | Descriptor: | PHOSPHATE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | Authors: | Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. | Deposit date: | 2000-05-24 | Release date: | 2000-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for specificity switching of the Src SH2 domain. Mol.Cell, 5, 2000
|
|
1JIC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jic by Molmil](/molmil-images/mine/1jic) | |
1X6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x6l by Molmil](/molmil-images/mine/1x6l) | Crystal structure of S. marcescens chitinase A mutant W167A | Descriptor: | Chitinase A | Authors: | Aronson Jr, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L. | Deposit date: | 2004-08-11 | Release date: | 2005-07-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mutation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A caused enhanced transglycosylation To be Published
|
|
1X6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x6n by Molmil](/molmil-images/mine/1x6n) | Crystal structure of S. marcescens chitinase A mutant W167A in complex with allosamidin | Descriptor: | 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, Chitinase A | Authors: | Aronson Jr, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L. | Deposit date: | 2004-08-11 | Release date: | 2005-07-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Muation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A causes enhanced transglycosylation To be Published
|
|
1TTO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tto by Molmil](/molmil-images/mine/1tto) | Crystal structure of the Rnase T1 variant R2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RNase T1 | Authors: | Hahn, U, Czaja, R, Perbandt, M, Betzel, C. | Deposit date: | 2004-06-23 | Release date: | 2005-09-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Purine activity of RNase T1RV is further improved by substitution of Trp59 by tyrosine Biochem.Biophys.Res.Commun., 336, 2005
|
|
7OSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7osd by Molmil](/molmil-images/mine/7osd) | |
7OS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7os8 by Molmil](/molmil-images/mine/7os8) | NMR SOLUTION STRUCTURE OF [Pro3,DLeu9]TL | Descriptor: | PHE-VAL-PRO-TRP-PHE-SER-LYS-PHE-DLE-GLY-ARG-ILE-LEU-NH2 | Authors: | Brancaccio, D, Carotenuto, A. | Deposit date: | 2021-06-08 | Release date: | 2021-08-11 | Last modified: | 2021-08-25 | Method: | SOLUTION NMR | Cite: | First-in-Class Cyclic Temporin L Analogue: Design, Synthesis, and Antimicrobial Assessment. J.Med.Chem., 64, 2021
|
|
5Z31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z31 by Molmil](/molmil-images/mine/5z31) | LPS bound solution structure of WS2-KG18 | Descriptor: | LYS-ASN-LYS-SER-ARG-VAL-ALA-ARG-GLY-TRP-GLY-ARG-LYS-CYS-PRO-LEU-PHE-GLY | Authors: | Bhunia, A, Mohid, S.A. | Deposit date: | 2018-01-05 | Release date: | 2019-02-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Application of tungsten disulfide quantum dot-conjugated antimicrobial peptides in bio-imaging and antimicrobial therapy. Colloids Surf B Biointerfaces, 176, 2019
|
|
5Z32
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z32 by Molmil](/molmil-images/mine/5z32) | LPS bound solution NMR structure of WS2-VR18 | Descriptor: | VAL-ALA-ARG-GLY-TRP-GLY-ARG-LYS-CYS-PRO-LEU-PHE-GLY-LYS-ASN-LYS-SER-ARG | Authors: | Bhunia, A, Mohid, S.A. | Deposit date: | 2018-01-05 | Release date: | 2019-02-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Application of tungsten disulfide quantum dot-conjugated antimicrobial peptides in bio-imaging and antimicrobial therapy. Colloids Surf B Biointerfaces, 176, 2019
|
|
6EY3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ey3 by Molmil](/molmil-images/mine/6ey3) | |
8GVN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gvn by Molmil](/molmil-images/mine/8gvn) | Novel salt-resistant antimicrobial peptide, RR14 | Descriptor: | TRP-LEU-ARG-ARG-ILE-LYS-ALA-TRP-LEU-ARG-ARG-ILE-LYS-ALA | Authors: | Lin, T.L, Tseng, T.S, Fan, P.J. | Deposit date: | 2022-09-15 | Release date: | 2022-11-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Deciphering Structure-Function Relationship Unveils Salt-Resistant Mode of Action of a Potent MRSA-Inhibiting Antimicrobial Peptide, RR14. J.Bacteriol., 204, 2022
|
|