7RNQ

Holo structure of engineered TrpB, 2B9-H275E, from Pyrococcus furiosus in the extended-open conformation

Summary for 7RNQ

Entry DOI	10.2210/pdb7rnq/pdb
Descriptor	Tryptophan synthase beta chain 1, PHOSPHATE ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	plp, tryptophan synthase, directed evolution, biosynthetic protein
Biological source	Pyrococcus furiosus
Total number of polymer chains	4
Total formula weight	174910.60
Authors	Higgins, P.M.,Buller, A.R. (deposition date: 2021-07-29, release date: 2022-08-03, Last modification date: 2023-11-15)
Primary citation	McDonald, A.D.,Higgins, P.M.,Buller, A.R. Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis. Nat Commun, 13:5242-5242, 2022 Cited by PubMed: 36068220 DOI: 10.1038/s41467-022-32789-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.102 Å)

Structure validation