9CAI
| High-resolution C. elegans 80S ribosome structure - class 2 | Descriptor: | 18S rRNA, 28S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | Authors: | Sehgal, E, Serrao, V.H.B, Arribere, J. | Deposit date: | 2024-06-17 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | High-Resolution Reconstruction of a C. elegans Ribosome Sheds Light on Evolutionary Dynamics and Tissue Specificity. Rna, 2024
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8ZYC
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8ZYD
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9CA1
| Human TOP3B-TDRD3 core complex in DNA religation state | Descriptor: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | Deposit date: | 2024-06-16 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics To Be Published
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9C9Y
| Human TOP3B-TDRD3 core complex in DNA pre-cleavage state | Descriptor: | DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*T)-3'), DNA topoisomerase 3-beta-1, MANGANESE (II) ION, ... | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | Deposit date: | 2024-06-16 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics To Be Published
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9CA0
| Human TOP3B-TDRD3 core complex in DNA pre-cleavage state | Descriptor: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | Authors: | Yang, X, Chen, X, Yang, W, Pommier, Y. | Deposit date: | 2024-06-16 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics To Be Published
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9C9Q
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9FQ2
| Poliovirus 3C protease in H32 spacegroup | Descriptor: | Protease 3C | Authors: | Fairhead, M, Lithgo, R.M, MacLean, E.M, Bowesman-Jones, H, Aschenbrenner, J.C, Balcomb, B.H, Capkin, E, Chandran, A.V, Godoy, A.S, Marples, P.G, Fearon, D, von Delft, F, Koekemoer, L. | Deposit date: | 2024-06-14 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Poliovirus 3C protease in H32 spacegroup To Be Published
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9FPZ
| Human NatA-MAP2 80S ribosome complex | Descriptor: | 28S rRNA (300-MER, fragments), 5.8S rRNA (58-MER), ... | Authors: | Klein, M.A, Wild, K, Sinning, I. | Deposit date: | 2024-06-14 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome To Be Published
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9FQ0
| Human NatA-NAC-MAP1 80S ribosome complex | Descriptor: | 28S rRNA, 5.8S rRNA, 60S ribosomal protein L19, ... | Authors: | Klein, M.A, Wild, K, Sinning, I. | Deposit date: | 2024-06-14 | Release date: | 2024-07-03 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.67 Å) | Cite: | Multi-protein assemblies orchestrate enzymatic processing of the nascent chain on the 80S ribosome To Be Published
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9C9R
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9C8U
| Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | Descriptor: | Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ... | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | Deposit date: | 2024-06-13 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min To Be Published
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8ZWI
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8ZWH
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8ZWK
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8ZWJ
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9FOY
| Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b | Descriptor: | (1~{R})-2-[4-[[4-bromanyl-3,5-bis(fluoranyl)phenyl]methylamino]cyclohexyl]-1-(6-methoxy-1,5-naphthyridin-4-yl)ethanol, (1~{S})-2-[4-[[4-bromanyl-3,5-bis(fluoranyl)phenyl]methylamino]cyclohexyl]-1-(6-methoxy-1,5-naphthyridin-4-yl)ethanol, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G)-3'), ... | Authors: | Kokot, M, Hrast, M, Feng, L, Mitchenall, L.A, Lawson, D.M, Maxwell, A, Minovski, N, Anderluh, M. | Deposit date: | 2024-06-12 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Unraveling the Mycobacterium tuberculosis DNA gyrase-DNA-NBTI complex To be published
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8ZV9
| Complex structure of HLA2402 with recognizing SARS-CoV-2 Y453F epitope NYNYLFRLF | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | Authors: | Deng, S.S, Jin, T.C, Xu, Z.H, Wang, M.H. | Deposit date: | 2024-06-11 | Release date: | 2024-08-21 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into immune escape at killer T cell epitope by SARS-CoV-2 Spike Y453F variants. J.Biol.Chem., 300, 2024
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8ZUG
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9C62
| P400 subcomplex of the native human TIP60 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | Deposit date: | 2024-06-07 | Release date: | 2024-08-21 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (5.28 Å) | Cite: | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 385, 2024
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9FMM
| Structure of human ACE2 in complex with a fluorinated small molecule inhibitor | Descriptor: | (2~{S})-2-[[(2~{S})-3-[3-[(3-chloranyl-5-fluoranyl-phenyl)methyl]imidazol-4-yl]-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-pentanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Benoit, R.B, Rodrigues, M.J, Wieser, M.M. | Deposit date: | 2024-06-06 | Release date: | 2024-07-17 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2. Eur J Nucl Med Mol Imaging, 2024
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9FMD
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9C4G
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9C3U
| Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTTTAC as recognition sequence | Descriptor: | DNA1, DNA2, Methyltransferase, ... | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | Deposit date: | 2024-06-02 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation. Nat Commun, 15, 2024
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9C3S
| Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTATAC as recognition sequence | Descriptor: | DNA1, DNA2, Methyltransferase, ... | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | Deposit date: | 2024-06-02 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation. Nat Commun, 15, 2024
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