9FOY

Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b

This is a non-PDB format compatible entry.

Summary for 9FOY

• Entry DOI: 10.2210/pdb9foy/pdb
• Descriptor: DNA gyrase subunit B,DNA gyrase subunit A, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G)-3'), DNA (5'-D(P*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... (5 entities in total)
• Functional Keywords: type iia topoisomerase, antibacterial, inhibitor, isomerase, fusion protein
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 6
• Total formula weight: 181960.52

Authors

Kokot, M.,Hrast, M.,Feng, L.,Mitchenall, L.A.,Lawson, D.M.,Maxwell, A.,Minovski, N.,Anderluh, M. (deposition date: 2024-06-12, release date: 2024-08-07)

• Primary citation: Kokot, M.,Hrast, M.,Feng, L.,Mitchenall, L.A.,Lawson, D.M.,Maxwell, A.,Minovski, N.,Anderluh, M.; Unraveling the Mycobacterium tuberculosis DNA gyrase-DNA-NBTI complex; To be published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)