9FOY
Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. VVEGDSAGG |
| Chain | Residue | Details |
| A | VAL457-GLY465 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01898 |
| Chain | Residue | Details |
| A | GLU459 | |
| A | ASP532 | |
| A | ASP534 | |
| B | GLU459 | |
| B | ASP532 | |
| B | ASP534 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Interaction with DNA => ECO:0000255|HAMAP-Rule:MF_01898 |
| Chain | Residue | Details |
| A | LYS484 | |
| A | ASN487 | |
| B | LYS484 | |
| B | ASN487 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255|HAMAP-Rule:MF_01897 |
| Chain | Residue | Details |
| A | TYR1129 | |
| B | TYR1129 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylthreonine => ECO:0007744|PubMed:21969609 |
| Chain | Residue | Details |
| A | THR1002 | |
| B | THR1002 |
