9FOY
Ternary complex of a Mycobacterium tuberculosis DNA gyrase core fusion with DNA and the inhibitor AMK32b
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA gyrase subunit B,DNA gyrase subunit A | polymer | 756 | 84383.9 | 2 | UniProt (P9WG45) UniProt (P9WG47) In PDB | Mycobacterium tuberculosis H37Rv | Type IIA topoisomerase subunit GyrA |
2 | E, G | DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G)-3') | polymer | 8 | 2451.6 | 2 | Mycobacterium tuberculosis H37Rv | ||
3 | F, H | DNA (5'-D(P*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3') | polymer | 12 | 3638.4 | 2 | synthetic construct | ||
4 | H | (1~{S})-2-[4-[[4-bromanyl-3,5-bis(fluoranyl)phenyl]methylamino]cyclohexyl]-1-(6-methoxy-1,5-naphthyridin-4-yl)ethanol | non-polymer | 506.4 | 1 | Chemie (A1ID8) | |||
5 | H | (1~{R})-2-[4-[[4-bromanyl-3,5-bis(fluoranyl)phenyl]methylamino]cyclohexyl]-1-(6-methoxy-1,5-naphthyridin-4-yl)ethanol | non-polymer | 506.4 | 1 | Chemie (A1ID9) |
Sequence modifications
A, B: 426 - 1001 (UniProt: P9WG45)
A, B: 1002 - 1500 (UniProt: P9WG47)
PDB | External Database | Details |
---|---|---|
Ser 423 | - | expression tag |
Asn 424 | - | expression tag |
Ala 425 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ile 1501 | - | expression tag |
Gly 1502 | - | expression tag |
Ser 1503 | - | expression tag |
Gly 1504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 180947.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1012.8 | |
All* | Total formula weight | 181960.5 |