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3WYF
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BU of 3wyf by Molmil
Crystal structure of Xpo1p-Yrb2p-Gsp1p-GTP complex
Descriptor: Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, Gsp1p, ...
Authors:Koyama, M, Shirai, N, Matsuura, Y.
Deposit date:2014-08-26
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural insights into how yrb2p accelerates the assembly of the xpo1p nuclear export complex
Cell Rep, 9, 2014
3WYG
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BU of 3wyg by Molmil
Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex
Descriptor: Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, Gsp1p, ...
Authors:Koyama, M, Shirai, N, Matsuura, Y.
Deposit date:2014-08-26
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into how yrb2p accelerates the assembly of the xpo1p nuclear export complex
Cell Rep, 9, 2014
3ZJY
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BU of 3zjy by Molmil
Crystal Structure of Importin 13 - RanGTP - eIF1A complex
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL, GTP-BINDING NUCLEAR PROTEIN RAN, ...
Authors:Gruenwald, M, Lazzaretti, D, Bono, F.
Deposit date:2013-01-21
Release date:2013-04-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
3LWW
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BU of 3lww by Molmil
Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit
Descriptor: Importin subunit beta-1, Snurportin-1
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2010-02-24
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta.
Biochemistry, 49, 2010
3M1I
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BU of 3m1i by Molmil
Crystal structure of yeast CRM1 (Xpo1p) in complex with yeast RanBP1 (Yrb1p) and yeast RanGTP (Gsp1pGTP)
Descriptor: Exportin-1, GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Koyama, M, Matsuura, Y.
Deposit date:2010-03-05
Release date:2010-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1
Embo J., 29, 2010
3NC1
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BU of 3nc1 by Molmil
Crystal structure of the CRM1-RanGTP complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NBY
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BU of 3nby by Molmil
Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3NC0
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BU of 3nc0 by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II)
Descriptor: DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3ND2
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BU of 3nd2 by Molmil
Structure of Yeast Importin-beta (Kap95p)
Descriptor: Importin subunit beta-1
Authors:Forwood, J.K, Kobe, B.
Deposit date:2010-06-06
Release date:2010-07-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures
Structure, 18, 2010
3NBZ
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BU of 3nbz by Molmil
Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I)
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
Deposit date:2010-06-04
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
2Z5O
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BU of 2z5o by Molmil
Complex of Transportin 1 with JKTBP NLS
Descriptor: Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1
Authors:Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2X19
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BU of 2x19 by Molmil
Crystal structure of Importin13 - RanGTP complex
Descriptor: GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ...
Authors:Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E.
Deposit date:2009-12-23
Release date:2010-02-16
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
2XWU
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BU of 2xwu by Molmil
CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX
Descriptor: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9
Authors:Gruenwald, M, Bono, F.
Deposit date:2010-11-05
Release date:2010-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation.
Embo J., 30, 2011
3A6P
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BU of 3a6p by Molmil
Crystal structure of Exportin-5:RanGTP:pre-miRNA complex
Descriptor: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ...
Authors:Okada, C, Yamashita, E, Lee, S.J, Shibata, S, Katahira, J, Nakagawa, A, Yoneda, Y, Tsukihara, T.
Deposit date:2009-09-07
Release date:2009-12-08
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:A high-resolution structure of the pre-microRNA nuclear export machinery
Science, 326, 2009
2Z5M
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BU of 2z5m by Molmil
Complex of Transportin 1 with TAP NLS, crystal form 2
Descriptor: Nuclear RNA export factor 1, Transportin-1
Authors:Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5N
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BU of 2z5n by Molmil
Complex of Transportin 1 with hnRNP D NLS
Descriptor: Heterogeneous nuclear ribonucleoprotein D0, Transportin-1
Authors:Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5J
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BU of 2z5j by Molmil
Free Transportin 1
Descriptor: Transportin-1
Authors:Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
Deposit date:2007-07-13
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5K
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BU of 2z5k by Molmil
Complex of Transportin 1 with TAP NLS
Descriptor: Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1
Authors:Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M.
Deposit date:2007-07-14
Release date:2007-10-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
5TQC
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BU of 5tqc by Molmil
Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4)
Descriptor: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1
Authors:Huber, F.M, Hoelz, A.
Deposit date:2016-10-23
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis for protection of ribosomal protein L4 from cellular degradation.
Nat Commun, 8, 2017
4HAT
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BU of 4hat by Molmil
Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-09-27
Release date:2013-01-09
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA, 110, 2013
5UWW
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BU of 5uww by Molmil
Crystal Structure of DEAF1 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
Descriptor: Deformed epidermal autoregulatory factor 1 homolog, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWP
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BU of 5uwp by Molmil
Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWO
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BU of 5uwo by Molmil
Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
6X2W
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BU of 6x2w by Molmil
Crystal Structure of PKINES peptide bound to CRM1(E571K)
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Baumhardt, J.M.
Deposit date:2020-05-21
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020

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數據於2024-06-19公開中

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