1LAU
 
 | | URACIL-DNA GLYCOSYLASE | | Descriptor: | DNA (5'-D(*TP*TP*T)-3'), PROTEIN (URACIL-DNA GLYCOSYLASE (E.C.3.2.2.-)) | | Authors: | Pearl, L.H, Savva, R. | | Deposit date: | 1996-01-03 | | Release date: | 1996-06-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structural basis of specific base-excision repair by uracil-DNA glycosylase.
Nature, 373, 1995
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1LQJ
 | | ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE | | Descriptor: | URACIL-DNA GLYCOSYLASE | | Authors: | Saikrishnan, K, Sagar, M.B, Ravishankar, R, Roy, S, Purnapatre, K, Varshney, U, Vijayan, M. | | Deposit date: | 2002-05-10 | | Release date: | 2002-11-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG.
Acta Crystallogr.,Sect.D, 58, 2002
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1MUG
 | | G:T/U MISMATCH-SPECIFIC DNA GLYCOSYLASE FROM E.COLI | | Descriptor: | PROTEIN (G:T/U SPECIFIC DNA GLYCOSYLASE), SULFATE ION | | Authors: | Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H. | | Deposit date: | 1998-07-10 | | Release date: | 1998-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
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1MWJ
 | | Crystal Structure of a MUG-DNA pseudo substrate complex | | Descriptor: | 5'-D(*CP*GP*CP*GP*A*GP*(DU)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | | Authors: | Barrett, T.E, Scharer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G.L, Pearl, L.H. | | Deposit date: | 2002-09-30 | | Release date: | 2002-10-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Crystal Structure of a thwarted mismatch glycosylase DNA repair complex
Embo J., 18, 1999
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1YUO
 | | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua) | | Descriptor: | Uracil-DNA glycosylase | | Authors: | Moe, E, Leiros, I, Riise, E.K, Olufsen, M, Lanes, O, Smalas, A.O, Willassen, N.P. | | Deposit date: | 2005-02-14 | | Release date: | 2005-03-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua)
J.Mol.Biol., 343, 2004
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1MTL
 | | Non-productive MUG-DNA complex | | Descriptor: | 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | | Authors: | Barrett, T.E, Savva, R, Barlow, T, Brown, T, Jiricny, J, Pearl, L.H. | | Deposit date: | 2002-09-21 | | Release date: | 2002-09-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of a DNA base-excision product resembling a cisplatin inter-strand adduct.
Nat.Struct.Biol., 5, 1998
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1MWI
 | | Crystal structure of a MUG-DNA product complex | | Descriptor: | 5'-D(*CP*GP*CP*GP*AP*GP*(AAB)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | | Authors: | Barrett, T.E, Savva, R, Panayotou, G, Brown, T, Barlow, T, Jiricny, J, Pearl, L.H. | | Deposit date: | 2002-09-30 | | Release date: | 2002-10-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions.
Cell(Cambridge,Mass.), 92, 1998
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5CYS
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1OE4
 | | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | | Descriptor: | 5'-D(*CP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*CP*TP*3DR*AP*CP*GP*GP*G)-3', GLYCEROL, ... | | Authors: | Wibley, J.E.A, Pearl, L.H. | | Deposit date: | 2003-03-19 | | Release date: | 2003-07-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and Specificity of the Vertebrate Anti-Mutator Uracil-DNA Glycosylase Smug1
Mol.Cell, 11, 2003
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3TKB
 | | crystal structure of human uracil-DNA glycosylase D183G/K302R mutant | | Descriptor: | IMIDAZOLE, Uracil-DNA glycosylase | | Authors: | Assefa, N.G, Niiranen, L, Willassen, N.P, Smalas, A.O, Moe, E. | | Deposit date: | 2011-08-26 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Thermal unfolding studies of cold adapted uracil-DNA N-glycosylase (UNG) from Atlantic cod (Gadus morhua). A comparative study with human UNG.
Comp.Biochem.Physiol. B: Biochem.Mol.Biol., 161, 2012
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3TR7
 | | Structure of a uracil-DNA glycosylase (ung) from Coxiella burnetii | | Descriptor: | Uracil-DNA glycosylase | | Authors: | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | Deposit date: | 2011-09-09 | | Release date: | 2011-09-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.1958 Å) | | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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2C2P
 | | The crystal structure of mismatch specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans | | Descriptor: | ACETATE ION, G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE | | Authors: | Moe, E, Leiros, I, Smalas, A.O, McSweeney, S. | | Deposit date: | 2005-09-29 | | Release date: | 2005-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Crystal Structure of Mismatch Specific Uracil-DNA Glycosylase (Mug) from Deinococcus Radiodurans Reveals a Novel Catalytic Residue and Broad Substrate Specificity
J.Biol.Chem., 281, 2006
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3UFM
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3UF7
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2C53
 | | A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 | | Descriptor: | 2'-DEOXYURIDINE, GLYCEROL, URACIL DNA GLYCOSYLASE | | Authors: | Krusong, K, Carpenter, E.P, Bellmy, S.R.W, Savva, R, Baldwin, G.S. | | Deposit date: | 2005-10-25 | | Release date: | 2005-11-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
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2C56
 | | A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 | | Descriptor: | URACIL DNA GLYCOSYLASE, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | Authors: | Krusong, K, Carpenter, E.P, Bellamy, S.R.W, Savva, R, Baldwin, G.S. | | Deposit date: | 2005-10-26 | | Release date: | 2005-11-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006
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3UFJ
 | | Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine | | Descriptor: | 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase | | Authors: | Pozharski, E, Maiti, A, Drohat, A.C. | | Deposit date: | 2011-11-01 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.967 Å) | | Cite: | Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2BOO
 | | The crystal structure of Uracil-DNA N-Glycosylase (UNG) from Deinococcus radiodurans. | | Descriptor: | NITRATE ION, URACIL-DNA GLYCOSYLASE | | Authors: | Leiros, I, Moe, E, Smalas, A.O, McSweeney, S. | | Deposit date: | 2005-04-13 | | Release date: | 2005-07-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the Uracil-DNA N-Glycosylase (Ung) from Deinococcus Radiodurans.
Acta Crystallogr.,Sect.D, 61, 2005
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3UO7
 | | Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate 5-carboxylcytosine | | Descriptor: | 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*AP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1CC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase | | Authors: | Zhang, L, He, C. | | Deposit date: | 2011-11-16 | | Release date: | 2012-02-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.002 Å) | | Cite: | Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Nat.Chem.Biol., 8, 2012
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3UOB
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2C2Q
 | | The crystal structure of mismatch specific uracil-DNA glycosylase (MUG) from Deinococcus radiodurans. Inactive mutant Asp93Ala. | | Descriptor: | ACETATE ION, G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE | | Authors: | Moe, E, Leiros, I, Smalas, A.O, McSweeney, S. | | Deposit date: | 2005-09-29 | | Release date: | 2005-10-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of Mismatch Specific Uracil-DNA Glycosylase (Mug) from Deinococcus Radiodurans Reveals a Novel Catalytic Residue and Broad Substrate Specificity
J.Biol.Chem., 281, 2006
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2D3Y
 | | Crystal structure of uracil-DNA glycosylase from Thermus Thermophilus HB8 | | Descriptor: | 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ACETATE ION, IRON/SULFUR CLUSTER, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-10-04 | | Release date: | 2006-10-17 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of family 5 uracil-DNA glycosylase bound to DNA.
J.Mol.Biol., 373, 2007
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2DDG
 | | Crystal structure of uracil-DNA glycosylase in complex with AP:G containing DNA | | Descriptor: | 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*AP*AP*GP*GP*CP*AP*AP*CP*A)-3', ACETATE ION, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Hoseki, J, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-01-28 | | Release date: | 2007-02-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of family 5 uracil-DNA glycosylase bound to DNA.
J.Mol.Biol., 373, 2007
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2DP6
 | | Crystal structure of uracil-DNA glycosylase in complex with AP:C containing DNA | | Descriptor: | 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*AP*AP*CP*GP*CP*AP*AP*CP*A)-3', DIHYDROGENPHOSPHATE ION, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Kuramitsu, S, Hoseki, J, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-05-07 | | Release date: | 2007-05-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of Family 5 Uracil-DNA Glycosylase Bound to DNA Reveals Insights into the Mechanism for Substrate Recognition and Catalysis
To be Published
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2DEM
 | | Crystal structure of Uracil-DNA glycosylase in complex with AP:A containing DNA | | Descriptor: | 5'-D(*AP*TP*GP*TP*TP*GP*CP*(D1P)P*TP*TP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*AP*AP*AP*GP*CP*AP*AP*CP*A)-3', DIHYDROGENPHOSPHATE ION, ... | | Authors: | Kosaka, H, Nakagawa, N, Masui, R, Hoseki, J, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-02-13 | | Release date: | 2007-04-24 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structure of family 5 uracil-DNA glycosylase bound to DNA.
J.Mol.Biol., 373, 2007
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