1SSP

WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA

Summary for 1SSP

Descriptor5'-D(*CP*TP*GP*TP*(D1P)P*AP*TP*CP*TP*T)-3', 5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3', URACIL-DNA GLYCOSYLASE, ... (5 entities in total)
Functional Keywordsdna glycosylase, dna base excision repair, uracil, dna, protein/dna, hydrolase-dna complex, hydrolase/dna
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Mitochondrion. Isoform 2: Nucleus P13051
Total number of polymer chains3
Total molecular weight31948.38
Authors
Parikh, S.S.,Mol, C.D.,Slupphaug, G.,Bharati, S.,Krokan, H.E.,Tainer, J.A. (deposition date: 1999-04-28, release date: 1999-05-06, Last modification date: 2011-07-13)
Primary citation
Parikh, S.S.,Mol, C.D.,Slupphaug, G.,Bharati, S.,Krokan, H.E.,Tainer, J.A.
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.
EMBO J., 17:5214-5226, 1998
PubMed: 9724657 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/17.17.5214
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers702.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution