1SSP

WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0004844	molecular_function	uracil DNA N-glycosylase activity
E	0006281	biological_process	DNA repair
E	0006284	biological_process	base-excision repair
E	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE URA E 55

Chain	Residue
A	ORP5
E	HOH804
E	GLY143
E	GLN144
E	ASP145
E	TYR147
E	CYS157
E	PHE158
E	ASN204
E	HIS268

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Functional Information from PROSITE/UniProt

site_id	PS00130
Number of Residues	10
Details	U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. KVVIlGQDPY

Chain	Residue	Details
E	LYS138-TYR147

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03166

Chain	Residue	Details
E	ASP145

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
E	LYS286

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1eug

Chain	Residue	Details
E	ASP145
E	HIS268

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