5ENS
 
 | | Rhodamine bound structure of bacterial efflux pump. | | Descriptor: | DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB, RHODAMINE 6G | | Authors: | Sjuts, H, Ornik, A.R, Pos, K.M. | | Deposit date: | 2015-11-09 | | Release date: | 2016-04-06 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
8DEU
 | |
8DEV
 | |
5EN5
 | | Apo structure of bacterial efflux pump. | | Descriptor: | DARPin, Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB | | Authors: | Sjuts, H, Ornik, A.R, Pos, K.M. | | Deposit date: | 2015-11-09 | | Release date: | 2016-04-06 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
8GJK
 | | Multi-drug efflux pump RE-CmeB bound with ampicillin | | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2023-03-16 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
|
|
8GJL
 | | multi-drug efflux pump RE-CmeB bound with Ciprofloxacin | | Descriptor: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2023-03-16 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
|
|
8GJJ
 | | Multi-drug efflux pump RE-CmeB Apo form | | Descriptor: | Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2023-03-15 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
|
|
8GK4
 | | Multi-drug efflux pump RE-CmeB bound with Chloramphenicol | | Descriptor: | CHLORAMPHENICOL, Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2023-03-17 | | Release date: | 2023-05-31 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
|
|
8GK0
 | | Multi-drug efflux pump RE-CmeB bound with Erythromycin | | Descriptor: | ERYTHROMYCIN A, Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2023-03-16 | | Release date: | 2023-06-07 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
|
|
8F4R
 | | Gentamicin bound aminoglycoside efflux pump AcrD | | Descriptor: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2022-11-11 | | Release date: | 2022-12-28 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity.
Mbio, 14, 2023
|
|
6SGT
 | | Cryo-EM structure of Escherichia coli AcrB and DARPin in Saposin A-nanodisc with cardiolipin | | Descriptor: | DARPin, Multidrug efflux pump subunit AcrB | | Authors: | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | | Deposit date: | 2019-08-05 | | Release date: | 2020-05-13 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment.
Structure, 28, 2020
|
|
6Q4N
 | | Fusidic acid bound AcrB_V340A | | Descriptor: | (2S)-3-hydroxypropane-1,2-diyl didecanoate, DARPin, DECANE, ... | | Authors: | Tam, H.K, Pos, K.M. | | Deposit date: | 2018-12-06 | | Release date: | 2019-11-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB.
J.Mol.Biol., 432, 2020
|
|
8F56
 | |
8F4N
 | | Dimer of aminoglycoside efflux pump AcrD | | Descriptor: | Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2022-11-11 | | Release date: | 2022-12-28 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity.
Mbio, 14, 2023
|
|
8F3E
 | | Trimer of aminoglycoside efflux pump AcrD | | Descriptor: | Efflux pump membrane transporter | | Authors: | Zhang, Z. | | Deposit date: | 2022-11-10 | | Release date: | 2022-12-28 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity.
Mbio, 14, 2023
|
|
8FFK
 | |
8FFS
 | |
6SGS
 | | Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc | | Descriptor: | DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB | | Authors: | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | | Deposit date: | 2019-08-05 | | Release date: | 2020-05-13 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment.
Structure, 28, 2020
|
|
6SGU
 | | Cryo-EM structure of Escherichia coli AcrB and DARPin in Saposin A-nanodisc | | Descriptor: | DARPin, Multidrug efflux pump subunit AcrB | | Authors: | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | | Deposit date: | 2019-08-05 | | Release date: | 2020-05-13 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment.
Structure, 28, 2020
|
|
6T7S
 | | MexB structure solved by cryo-EM in nanodisc in absence of its protein partners | | Descriptor: | Efflux pump membrane transporter | | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | | Deposit date: | 2019-10-23 | | Release date: | 2020-09-16 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11, 2020
|
|
1OY9
 | | Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | | Descriptor: | Acriflavine resistance protein B, ETHIDIUM | | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | | Deposit date: | 2003-04-03 | | Release date: | 2003-05-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
|
|
1OYD
 | | Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | | Descriptor: | Acriflavine resistance protein B, DEQUALINIUM | | Authors: | Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | | Deposit date: | 2003-04-03 | | Release date: | 2003-05-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
|
|
1T9U
 | |
1T9V
 | |
1T9X
 | |
