8GJK

Multi-drug efflux pump RE-CmeB bound with ampicillin

Summary for 8GJK

Entry DOI	10.2210/pdb8gjk/pdb
EMDB information	40092
Descriptor	Efflux pump membrane transporter, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (2 entities in total)
Functional Keywords	efflux pump, membrane protein
Biological source	Campylobacter jejuni
Total number of polymer chains	3
Total formula weight	342734.85
Authors	Zhang, Z. (deposition date: 2023-03-16, release date: 2023-05-31, Last modification date: 2023-10-04)
Primary citation	Zhang, Z.,Lizer, N.,Wu, Z.,Morgan, C.E.,Yan, Y.,Zhang, Q.,Yu, E.W. Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance. Microbiol Spectr, 11:e0119723-e0119723, 2023 Cited by PubMed: 37289051 DOI: 10.1128/spectrum.01197-23 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.16 Å)

Structure validation