6SGS

Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc

Summary for 6SGS

Entry DOI	10.2210/pdb6sgs/pdb
EMDB information	10183
Descriptor	Multidrug efflux pump subunit AcrB, DARPin, Multidrug efflux pump accessory protein AcrZ (3 entities in total)
Functional Keywords	rnd transporter, efflux pump, drug transport, antibiotic resistance, lipid nanodisc, membrane protein
Biological source	Escherichia coli K12 More
Total number of polymer chains	8
Total formula weight	393543.94
Authors	Szewczak-Harris, A.,Du, D.,Newman, C.,Neuberger, A.,Luisi, B.F. (deposition date: 2019-08-05, release date: 2020-05-13, Last modification date: 2020-06-10)
Primary citation	Du, D.,Neuberger, A.,Orr, M.W.,Newman, C.E.,Hsu, P.C.,Samsudin, F.,Szewczak-Harris, A.,Ramos, L.M.,Debela, M.,Khalid, S.,Storz, G.,Luisi, B.F. Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Structure, 28:625-, 2020 Cited by PubMed: 32348749 DOI: 10.1016/j.str.2020.03.013 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation