5ENS

Rhodamine bound structure of bacterial efflux pump.

Summary for 5ENS

Entry DOI	10.2210/pdb5ens/pdb
Descriptor	Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB, DARPin, RHODAMINE 6G, ... (4 entities in total)
Functional Keywords	efflux pump, transport protein
Biological source	Escherichia coli K-12 More
Cellular location	Cell inner membrane ; Multi- pass membrane protein : P31224
Total number of polymer chains	6
Total formula weight	252618.22
Authors	Sjuts, H.,Ornik, A.R.,Pos, K.M. (deposition date: 2015-11-09, release date: 2016-04-06, Last modification date: 2024-01-10)
Primary citation	Sjuts, H.,Vargiu, A.V.,Kwasny, S.M.,Nguyen, S.T.,Kim, H.S.,Ding, X.,Ornik, A.R.,Ruggerone, P.,Bowlin, T.L.,Nikaido, H.,Pos, K.M.,Opperman, T.J. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives. Proc.Natl.Acad.Sci.USA, 113:3509-3514, 2016 Cited by PubMed: 26976576 DOI: 10.1073/pnas.1602472113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation