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3NSJ
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BU of 3nsj by Molmil
The X-ray crystal structure of lymphocyte perforin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Law, R.H, Whisstock, J.C, Caradoc-Davies, T.T.
Deposit date:2010-07-01
Release date:2010-11-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structural basis for membrane binding and pore formation by lymphocyte perforin.
Nature, 468, 2010
3PFQ
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BU of 3pfq by Molmil
Crystal Structure and Allosteric Activation of Protein Kinase C beta II
Descriptor: CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein kinase C beta type, ...
Authors:Leonard, T.A, Rozycki, B, Saidi, L.F, Hummer, G, Hurley, J.H.
Deposit date:2010-10-28
Release date:2011-02-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure and Allosteric Activation of Protein Kinase C beta II
Cell(Cambridge,Mass.), 144, 2011
3PYC
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BU of 3pyc by Molmil
Crystal structure of human SMURF1 C2 domain
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase SMURF1, SULFATE ION
Authors:Li, X, Li, P.
Deposit date:2010-12-13
Release date:2011-04-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of human SMURF1 C2 domain
To be Published
3RDJ
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BU of 3rdj by Molmil
Rat PKC C2 domain Apo
Descriptor: Protein kinase C alpha type
Authors:Li, P.
Deposit date:2011-04-01
Release date:2011-09-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Pb2+ as modulator of protein-membrane interactions.
J.Am.Chem.Soc., 133, 2011
3RPB
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BU of 3rpb by Molmil
THE C2B-DOMAIN OF RABPHILIN: STRUCTURAL VARIATIONS IN A JANUS-FACED DOMAIN
Descriptor: RABPHILIN 3-A
Authors:Ubach, J, Garcia, J, Nittler, M.P, Sudhof, T.C, Rizo, J.
Deposit date:1999-04-19
Release date:1999-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Janus-faced C2B domain of rabphilin.
Nat.Cell Biol., 1, 1999
3TWY
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BU of 3twy by Molmil
RAT PKC C2 DOMAIN BOUND TO PB
Descriptor: LEAD (II) ION, Protein kinase C alpha type, SULFATE ION
Authors:Li, P.
Deposit date:2011-09-22
Release date:2011-11-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Pb2+ as Modulator of Protein-Membrane Interactions.
J.Am.Chem.Soc., 133, 2011
3W56
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BU of 3w56 by Molmil
Structure of a C2 domain
Descriptor: C2 domain protein
Authors:Traore, D.A.K, Whisstock, J.C.
Deposit date:2013-01-24
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem.J., 456, 2013
3W57
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BU of 3w57 by Molmil
Structure of a C2 domain
Descriptor: C2 domain protein, CALCIUM ION
Authors:Traore, D.A.K, Whisstock, J.C.
Deposit date:2013-01-24
Release date:2013-10-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem.J., 456, 2013
4DNL
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BU of 4dnl by Molmil
Crystal structure of a C2 domain of a protein kinase C alpha (PRKCA) from Homo sapiens at 1.90 A resolution
Descriptor: Protein kinase C alpha type, SODIUM ION
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2012-02-08
Release date:2012-02-22
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a C2 domain of a protein kinase C alpha (PRKCA) from Homo sapiens at 1.90 A resolution
To be published
4GNK
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BU of 4gnk by Molmil
Crystal structure of Galphaq in complex with full-length human PLCbeta3
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Lyon, A.M, Tesmer, J.J.G.
Deposit date:2012-08-17
Release date:2013-02-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Full-length G alpha (q)-phospholipase C-beta 3 structure reveals interfaces of the C-terminal coiled-coil domain.
Nat.Struct.Mol.Biol., 20, 2013
4ICW
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BU of 4icw by Molmil
N-terminal C2 domain of human CEP120
Descriptor: Centrosomal protein of 120 kDa
Authors:Janowski, R, Guarin, N, Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:N-terminal C2 domain tandem of human CEP120 shows lipid binding properties
To be Published
4ICX
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BU of 4icx by Molmil
N-terminal C2 domain of human CEP120
Descriptor: Centrosomal protein of 120 kDa
Authors:Janowski, R, Guarin, N, Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:N-terminal C2 domain tandem of human CEP120 shows lipid binding properties
To be Published
4IHB
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BU of 4ihb by Molmil
X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN
Descriptor: CALCIUM ION, Dysferlin, FORMIC ACID
Authors:Sutton, R.B, Fuson, K.L.
Deposit date:2012-12-18
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair.
Structure, 22, 2014
4IQH
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BU of 4iqh by Molmil
Crystal Structure Analysis of Dysferlin C2A variant 1 (C2Av1)
Descriptor: Dysferlin
Authors:Sutton, R.B, Fuson, K.L.
Deposit date:2013-01-11
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair.
Structure, 22, 2014
4L1L
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BU of 4l1l by Molmil
Rat PKC C2 domain bound to CD
Descriptor: CADMIUM ION, Protein kinase C alpha type, SULFATE ION
Authors:Morales, K.M, Yang, Y, Long, Z, Li, P, Taylor, A.B, Hart, P.J, Igumenova, T.I.
Deposit date:2013-06-03
Release date:2013-08-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cd(2+) as a ca(2+) surrogate in protein-membrane interactions: isostructural but not isofunctional.
J.Am.Chem.Soc., 135, 2013
4LCV
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BU of 4lcv by Molmil
Crystal Structure of DOC2B C2A domain
Descriptor: BETA-MERCAPTOETHANOL, CALCIUM ION, CITRATE ANION, ...
Authors:Giladi, M, Almagor, L, Hirsch, J.A.
Deposit date:2013-06-23
Release date:2013-09-11
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis.
J.Mol.Biol., 425, 2013
4LDC
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BU of 4ldc by Molmil
Crystal Structure of DOC2B C2B domain
Descriptor: CALCIUM ION, CITRATE ANION, Double C2-like domain-containing protein beta
Authors:Giladi, M, Almagor, L, Hirsch, J.A.
Deposit date:2013-06-24
Release date:2013-09-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.264 Å)
Cite:The C2B Domain Is the Primary Ca(2+) Sensor in DOC2B: A Structural and Functional Analysis.
J.Mol.Biol., 425, 2013
4LT7
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BU of 4lt7 by Molmil
Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium
Descriptor: CALCIUM ION, Rabphilin-3A
Authors:Verdaguer, N, Ferrer-Orta, C, Buxaderas, M, Corbalan-Garcia, S, Perez-Sanchez, D, Guerrero-Valero, M, Luengo, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Guillen, J.
Deposit date:2013-07-23
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4MJJ
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BU of 4mjj by Molmil
Crystal structure of the C2A domain of DOC2A
Descriptor: Double C2-like domain-containing protein alpha
Authors:Huang, Q.Q.
Deposit date:2013-09-03
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the C2A domain of DOC2A
To be Published
4NP9
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BU of 4np9 by Molmil
Structure of Rabphilin C2A domain bound to IP3
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rabphilin-3A, SULFATE ION
Authors:Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-Sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S.
Deposit date:2013-11-21
Release date:2013-12-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NPJ
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BU of 4npj by Molmil
Extended-Synaptotagmin 2, C2A- and C2B-domains
Descriptor: ACETATE ION, CHLORIDE ION, Extended synaptotagmin-2, ...
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2013-11-21
Release date:2014-01-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.
Structure, 22, 2014
4NPK
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BU of 4npk by Molmil
Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound
Descriptor: CALCIUM ION, Extended synaptotagmin-2
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2013-11-21
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.552 Å)
Cite:Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2.
Structure, 22, 2014
4NS0
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BU of 4ns0 by Molmil
The C2A domain of Rabphilin 3A in complex with PI(4,5)P2
Descriptor: Rabphilin-3A, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S.
Deposit date:2013-11-27
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4P42
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BU of 4p42 by Molmil
Extended-Synaptotagmin 2, SMP - C2A - C2B Domains
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, Extended synaptotagmin-2
Authors:Schauder, C.M, Wu, X, Reinisch, K.M.
Deposit date:2014-03-10
Release date:2014-05-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.
Nature, 510, 2014
4QJ3
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BU of 4qj3 by Molmil
Structure of a fragment of human phospholipase C-beta3 delta472-559, in complex with Galphaq
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Lyon, A.M, Tesmer, J.J.G.
Deposit date:2014-06-03
Release date:2014-10-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular mechanisms of phospholipase C beta 3 autoinhibition.
Structure, 22, 2014

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數據於2024-11-13公開中

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