6IIR
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6IIP
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![BU of 6iip by Molmil](/molmil-images/mine/6iip) | Apo-form structure of the HRP3 PWWP domain | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hepatoma-derived growth factor-related protein 3, SULFATE ION | Authors: | Wang, Z, Tian, W. | Deposit date: | 2018-10-07 | Release date: | 2019-04-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (0.951 Å) | Cite: | Apo-form structure of the HRP3 PWWP domain Nucleic Acids Res., 2019
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4QXC
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4QWN
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4QXH
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![BU of 4qxh by Molmil](/molmil-images/mine/4qxh) | |
4QX7
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4TN7
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![BU of 4tn7 by Molmil](/molmil-images/mine/4tn7) | Crystal structure of mouse KDM2A-H3K36ME-NO complex | Descriptor: | FE (III) ION, Lysine-specific demethylase 2A, NITRIC OXIDE, ... | Authors: | Cheng, Z. | Deposit date: | 2014-06-03 | Release date: | 2015-05-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes Dev., 28, 2014
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6ZV1
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![BU of 6zv1 by Molmil](/molmil-images/mine/6zv1) | TFIIS N-terminal domain (TND) from human IWS1 | Descriptor: | Protein IWS1 homolog | Authors: | Veverka, V. | Deposit date: | 2020-07-23 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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6ZV3
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![BU of 6zv3 by Molmil](/molmil-images/mine/6zv3) | TFIIS N-terminal domain (TND) from human MED26 | Descriptor: | Mediator of RNA polymerase II transcription subunit 26 | Authors: | Veverka, V. | Deposit date: | 2020-07-23 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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6ZV2
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![BU of 6zv2 by Molmil](/molmil-images/mine/6zv2) | TFIIS N-terminal domain (TND) from human PPP1R10 | Descriptor: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | Authors: | Veverka, V. | Deposit date: | 2020-07-23 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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7AT8
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![BU of 7at8 by Molmil](/molmil-images/mine/7at8) | Histone H3 recognition by nucleosome-bound PRC2 subunit EZH2. | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3.2, ... | Authors: | Finogenova, K, Benda, C, Schaefer, I.B, Poepsel, S, Strauss, M, Mueller, J. | Deposit date: | 2020-10-29 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3. Elife, 9, 2020
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6ZUZ
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6ZV4
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![BU of 6zv4 by Molmil](/molmil-images/mine/6zv4) | Human TFIIS N-terminal domain in complex with IWS1 | Descriptor: | Transcription elongation factor A protein 1,Protein IWS1 homolog | Authors: | Veverka, V. | Deposit date: | 2020-07-23 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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6ZV0
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![BU of 6zv0 by Molmil](/molmil-images/mine/6zv0) | TFIIS N-terminal domain (TND) from human LEDGF/p75 | Descriptor: | PC4 and SFRS1-interacting protein | Authors: | Veverka, V. | Deposit date: | 2020-07-23 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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6ZUY
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![BU of 6zuy by Molmil](/molmil-images/mine/6zuy) | Human TFIIS N-terminal domain (TND) | Descriptor: | Transcription elongation factor A protein 1 | Authors: | Veverka, V. | Deposit date: | 2020-07-23 | Release date: | 2021-12-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
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2MSR
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![BU of 2msr by Molmil](/molmil-images/mine/2msr) | Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160) | Descriptor: | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein | Authors: | Cermakova, K, Tesina, P, Demeulemeester, J, El Ashkar, S, Mereau, H, Schwaller, J, Rezacova, P, Veverka, V, De Rijck, J. | Deposit date: | 2014-08-05 | Release date: | 2014-08-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia. Cancer Res., 74, 2014
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2N3A
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![BU of 2n3a by Molmil](/molmil-images/mine/2n3a) | Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404) | Descriptor: | PC4 and SFRS1-interacting protein, Pogo transposable element with ZNF domain | Authors: | Tesina, P, Cermakova, K, Horejsi, M, Prochazkova, K, Fabry, M, Sharma, S, Christ, F, Demeulemeester, J, Debyser, Z, De Rijck, J, Veverka, V, Rezacova, P. | Deposit date: | 2015-05-26 | Release date: | 2015-08-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif. Nat Commun, 6, 2015
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2OS2
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![BU of 2os2 by Molmil](/molmil-images/mine/2os2) | Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys36 | Descriptor: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-05 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
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2OT7
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![BU of 2ot7 by Molmil](/molmil-images/mine/2ot7) | Crystal structure of JMJD2A complexed with histone H3 peptide monomethylated at Lys9 | Descriptor: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-07 | Release date: | 2007-03-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.135 Å) | Cite: | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
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2OX0
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![BU of 2ox0 by Molmil](/molmil-images/mine/2ox0) | Crystal structure of JMJD2A complexed with histone H3 peptide dimethylated at Lys9 | Descriptor: | CHLORIDE ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ... | Authors: | Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-19 | Release date: | 2007-03-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
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2Q8C
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![BU of 2q8c by Molmil](/molmil-images/mine/2q8c) | Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, HISTONE 3 PEPTIDE, JmjC domain-containing histone demethylation protein 3A, ... | Authors: | Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C. | Deposit date: | 2007-06-10 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat.Struct.Mol.Biol., 14, 2007
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2Q8D
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![BU of 2q8d by Molmil](/molmil-images/mine/2q8d) | Crystal structure of JMJ2D2A in ternary complex with histone H3-K36me2 and succinate | Descriptor: | HISTONE 3 peptide, JmjC domain-containing histone demethylation protein 3A, NICKEL (II) ION, ... | Authors: | Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C. | Deposit date: | 2007-06-10 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat.Struct.Mol.Biol., 14, 2007
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2Q8E
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![BU of 2q8e by Molmil](/molmil-images/mine/2q8e) | Specificity and Mechanism of JMJD2A, a Trimethyllysine-Specific Histone Demethylase | Descriptor: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C. | Deposit date: | 2007-06-10 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat.Struct.Mol.Biol., 14, 2007
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2OQ6
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![BU of 2oq6 by Molmil](/molmil-images/mine/2oq6) | Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys9 | Descriptor: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-01-31 | Release date: | 2007-03-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
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2OQ7
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![BU of 2oq7 by Molmil](/molmil-images/mine/2oq7) | The crystal structure of JMJD2A complexed with Ni and N-oxalylglycine | Descriptor: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-01-31 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
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