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7LUL
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BU of 7lul by Molmil
Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S.
Deposit date:2021-02-22
Release date:2021-07-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
J.Mol.Biol., 433, 2021
7LC2
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BU of 7lc2 by Molmil
Crystal Structure of KRAS4b-Q61R (GMPPNP-bound) in complex with the RAS-binding domain (RBD) of SIN1
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dharmaiah, S, Simanshu, D.K.
Deposit date:2021-01-09
Release date:2021-07-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LC1
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Crystal Structure of KRAS4b (GMPPNP-bound) in complex with the RBD-PH domains of SIN1
Descriptor: Isoform 2B of GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dharmaiah, S, Simanshu, D.K.
Deposit date:2021-01-09
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Proc.Natl.Acad.Sci.USA, 118, 2021
3B08
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BU of 3b08 by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
Descriptor: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION, ...
Authors:Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
Deposit date:2011-06-07
Release date:2011-12-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
7W3H
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BU of 7w3h by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7W39
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BU of 7w39 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.1_UBL
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
Deposit date:2021-11-25
Release date:2022-05-04
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
7LPY
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BU of 7lpy by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
7LPZ
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BU of 7lpz by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
7LNY
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BU of 7lny by Molmil
Apo structure of the Histone chaperone ASF1A residues 1-155
Descriptor: Histone chaperone ASF1A
Authors:Simon, B, Boggon, T.J, Calderwood, D, Turk, B.E.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
7LQ0
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BU of 7lq0 by Molmil
Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases
Descriptor: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ...
Authors:Thapar, R, Andrew, A.S, Tainer, J.A.
Deposit date:2021-02-12
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases
To Be Published
7LO0
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BU of 7lo0 by Molmil
Structure of human ASF1a in complex with a TLK2 peptide
Descriptor: Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2
Authors:Simon, B, Calderwood, D, Turk, B.E, Boggon, T.J.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
7MC3
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BU of 7mc3 by Molmil
Solution structure of Miz-1 zinc finger 12
Descriptor: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
Authors:Boisvert, O, Lavigne, P.
Deposit date:2021-04-01
Release date:2021-04-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MC1
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BU of 7mc1 by Molmil
Solution structure of Miz-1 Zinc finger 10
Descriptor: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
Authors:Boisvert, O, Lavigne, P.
Deposit date:2021-04-01
Release date:2021-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7MC2
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BU of 7mc2 by Molmil
Solution structure of Miz-1 Zinc finger 11 H586Y
Descriptor: Isoform 2 of Zinc finger and BTB domain-containing protein 17, ZINC ION
Authors:Boisvert, O, Lavigne, P.
Deposit date:2021-04-01
Release date:2021-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Zinc Fingers 10 and 11 of Miz-1 undergo conformational exchange to achieve specific DNA binding.
Structure, 30, 2022
7M10
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BU of 7m10 by Molmil
PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1
Descriptor: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2021-03-11
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Biochem.J., 478, 2021
7MJU
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BU of 7mju by Molmil
Crystal structure of human AF10 PZP bound to histone H3 tail
Descriptor: Histone H3.1,Protein AF-10, ZINC ION
Authors:Klein, B.J, Kutateladze, T.G.
Deposit date:2021-04-20
Release date:2021-08-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Nat Commun, 12, 2021
7N5S
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BU of 7n5s by Molmil
ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6)
Descriptor: DNA Strand I, DNA Strand II, ZINC ION, ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2021-06-06
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
7MYF
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BU of 7myf by Molmil
Ubiquitin variant UbV.k.1 in complex with Ube2k
Descriptor: Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K
Authors:Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
Deposit date:2021-05-21
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
7N5T
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BU of 7n5t by Molmil
ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5)
Descriptor: DNA Strand I, DNA Strand II, ZINC ION, ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2021-06-06
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
7MYH
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BU of 7myh by Molmil
Ubiquitin variant UbV.k.2 in complex with Ube2k
Descriptor: GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K
Authors:Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
Deposit date:2021-05-21
Release date:2021-08-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
7MZT
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BU of 7mzt by Molmil
Borrelia burgdorferi BBK32-C in complex with an autolytic fragment of human C1r at 4.1A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, ...
Authors:Garcia, B.L.
Deposit date:2021-05-24
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.07 Å)
Cite:A Structural Basis for Inhibition of the Complement Initiator Protease C1r by Lyme Disease Spirochetes.
J Immunol., 207, 2021
6QJA
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BU of 6qja by Molmil
Organizational principles of the NuMA-Dynein interaction interface and implications for mitotic spindle functions
Descriptor: CHLORIDE ION, MAGNESIUM ION, Nuclear mitotic apparatus protein 1
Authors:Renna, C, Rizzelli, F, Carminati, M, Gaddoni, C, Pirovano, L, Cecatiello, V, Pasqualato, S, Mapelli, M.
Deposit date:2019-01-23
Release date:2020-02-05
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Organizational Principles of the NuMA-Dynein Interaction Interface and Implications for Mitotic Spindle Functions.
Structure, 28, 2020
3CXB
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BU of 3cxb by Molmil
Crystal Structure of sifa and skip
Descriptor: Pleckstrin homology domain-containing family M member 2, Protein sifA
Authors:Huang, Z, Chai, J.
Deposit date:2008-04-24
Release date:2008-12-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation
Cell Host Microbe, 4, 2008
7N85
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BU of 7n85 by Molmil
Inner ring spoke from the isolated yeast NPC
Descriptor: Nucleoporin ASM4, Nucleoporin NIC96, Nucleoporin NSP1, ...
Authors:Akey, C.W, Rout, M.P, Ouch, C, Echevarria, I, Fernandez-Martinez, J, Nudelman, I.
Deposit date:2021-06-13
Release date:2022-01-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell, 185, 2022
7N9F
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BU of 7n9f by Molmil
Structure of the in situ yeast NPC
Descriptor: Dynein light chain 1, cytoplasmic, Nucleoporin 145c, ...
Authors:Villa, E, Singh, D, Ludtke, S.J, Akey, C.W, Rout, M.P, Echeverria, I, Suslov, S.
Deposit date:2021-06-17
Release date:2022-01-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (37 Å)
Cite:Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell, 185, 2022

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數據於2024-09-11公開中

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