7LO0

Structure of human ASF1a in complex with a TLK2 peptide

Summary for 7LO0

Entry DOI	10.2210/pdb7lo0/pdb
Descriptor	Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2 (3 entities in total)
Functional Keywords	histone chaperone, kinase, docking, nucleosome assembly, cell cycle
Biological source	Homo sapiens (Human) More
Total number of polymer chains	24
Total formula weight	182635.60
Authors	Simon, B.,Calderwood, D.,Turk, B.E.,Boggon, T.J. (deposition date: 2021-02-08, release date: 2022-02-16, Last modification date: 2023-10-18)
Primary citation	Simon, B.,Lou, H.J.,Huet-Calderwood, C.,Shi, G.,Boggon, T.J.,Turk, B.E.,Calderwood, D.A. Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nat Commun, 13:749-749, 2022 Cited by PubMed: 35136069 DOI: 10.1038/s41467-022-28427-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation