8UO4
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![BU of 8uo4 by Molmil](/molmil-images/mine/8uo4) | CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class T) | Descriptor: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Papasergi-Scott, M.M, Skiniotis, G. | Deposit date: | 2023-10-19 | Release date: | 2024-03-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8UNP
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![BU of 8unp by Molmil](/molmil-images/mine/8unp) | CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class E) | Descriptor: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Papasergi-Scott, M.M, Skiniotis, G. | Deposit date: | 2023-10-19 | Release date: | 2024-03-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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8UNU
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![BU of 8unu by Molmil](/molmil-images/mine/8unu) | CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class J) | Descriptor: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Papasergi-Scott, M.M, Skiniotis, G. | Deposit date: | 2023-10-19 | Release date: | 2024-03-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
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6TFN
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![BU of 6tfn by Molmil](/molmil-images/mine/6tfn) | |
7RBT
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![BU of 7rbt by Molmil](/molmil-images/mine/7rbt) | cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide | Descriptor: | 2-fluoro-4-[(1R)-6-methoxy-1-methyl-2-{(1S)-1-[4-(propan-2-yl)phenyl]ethyl}-1,2,3,4-tetrahydroisoquinolin-5-yl]-6-[(2-methylpropyl)amino]phenol, Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Sun, B, Kobilka, B.K, Sloop, K.W, Feng, D, Kobilka, T.S. | Deposit date: | 2021-07-06 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Structural determinants of dual incretin receptor agonism by tirzepatide. Proc.Natl.Acad.Sci.USA, 119, 2022
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7RGP
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![BU of 7rgp by Molmil](/molmil-images/mine/7rgp) | cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, B, Kobilka, B.K, Sloop, K.W, Feng, D, Kobilka, T.S. | Deposit date: | 2021-07-15 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural determinants of dual incretin receptor agonism by tirzepatide. Proc.Natl.Acad.Sci.USA, 119, 2022
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7RG9
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![BU of 7rg9 by Molmil](/molmil-images/mine/7rg9) | cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, B, Kobilka, B.K, Sloop, K.W, Feng, D, Kobilka, T.S. | Deposit date: | 2021-07-14 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural determinants of dual incretin receptor agonism by tirzepatide. Proc.Natl.Acad.Sci.USA, 119, 2022
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7RA3
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![BU of 7ra3 by Molmil](/molmil-images/mine/7ra3) | cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP | Descriptor: | Gastric inhibitory polypeptide, Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Sun, B, Kobilka, B.K, Sloop, K.W, Feng, D, Kobilka, T.S. | Deposit date: | 2021-06-29 | Release date: | 2022-04-13 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structural determinants of dual incretin receptor agonism by tirzepatide. Proc.Natl.Acad.Sci.USA, 119, 2022
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7R40
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![BU of 7r40 by Molmil](/molmil-images/mine/7r40) | Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 87G7 heavy chain variable region, ... | Authors: | Hurdiss, D.L. | Deposit date: | 2022-02-08 | Release date: | 2022-04-20 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern. Sci Immunol, 7, 2022
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6T7X
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![BU of 6t7x by Molmil](/molmil-images/mine/6t7x) | Crystal structure of PCNA from P. abyssi | Descriptor: | DNA polymerase sliding clamp | Authors: | Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L. | Deposit date: | 2019-10-23 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
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7YZY
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![BU of 7yzy by Molmil](/molmil-images/mine/7yzy) | pMMO structure from native membranes by cryoET and STA | Descriptor: | Methane monooxygenase subunit C2, Particulate methane monooxygenase alpha subunit, Particulate methane monooxygenase beta subunit | Authors: | Zhu, Y, Ni, T, Zhang, P. | Deposit date: | 2022-02-21 | Release date: | 2022-08-10 | Last modified: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure and activity of particulate methane monooxygenase arrays in methanotrophs. Nat Commun, 13, 2022
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7ZFX
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![BU of 7zfx by Molmil](/molmil-images/mine/7zfx) | VDR complex with Aromatic-D-Ring Analog | Descriptor: | (1R,3S,5Z)-5-[(E)-3-[3,5-bis(6-methyl-6-oxidanyl-heptyl)phenyl]prop-2-enylidene]-4-methylidene-cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... | Authors: | Rochel, N. | Deposit date: | 2022-04-01 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3. J.Med.Chem., 65, 2022
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7ZFG
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![BU of 7zfg by Molmil](/molmil-images/mine/7zfg) | VDR complex with aromatic D-ring analog | Descriptor: | (1R,3S,5Z)-4-methylidene-5-[(E)-9-methyl-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]-9-oxidanyl-dec-2-enylidene]cyclohexane-1,3-diol, ACETATE ION, Nuclear receptor coactivator 1, ... | Authors: | Rochel, N. | Deposit date: | 2022-04-01 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3. J.Med.Chem., 65, 2022
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2JY9
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![BU of 2jy9 by Molmil](/molmil-images/mine/2jy9) | NMR structure of putative tRNA hydrolase domain from Salmonella typhimurium. NorthEast Structural Genomics Consortium target StR220 | Descriptor: | Putative tRNA hydrolase domain | Authors: | Singarapu, K.K, Wu, Y, Sukumaran, D, Eletsky, A, Zeri, A, Wang, D, Janjua, H, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-12-07 | Release date: | 2008-01-01 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structure of putative tRNA hydrolase domain from Salmonella typhimurium. To be Published
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7ZMD
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7ZMC
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7ZMA
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7ZM9
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![BU of 7zm9 by Molmil](/molmil-images/mine/7zm9) | Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase | Authors: | Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. | Deposit date: | 2022-04-19 | Release date: | 2022-09-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
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7ZMF
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![BU of 7zmf by Molmil](/molmil-images/mine/7zmf) | Dehydratase domain of module 3 from Brevibacillus Brevis orphan BGC11 | Descriptor: | GLYCEROL, MAGNESIUM ION, Putative polyketide synthase | Authors: | Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. | Deposit date: | 2022-04-19 | Release date: | 2022-09-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
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7KDT
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![BU of 7kdt by Molmil](/molmil-images/mine/7kdt) | |
7ZSK
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![BU of 7zsk by Molmil](/molmil-images/mine/7zsk) | |
8ATM
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8ATO
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![BU of 8ato by Molmil](/molmil-images/mine/8ato) | |
7VKV
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![BU of 7vkv by Molmil](/molmil-images/mine/7vkv) | |
4Z98
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![BU of 4z98 by Molmil](/molmil-images/mine/4z98) | Crystal Structure of Hen Egg White Lysozyme using Serial X-ray Diffraction Data Collection | Descriptor: | ACETATE ION, Lysozyme C | Authors: | Murray, T.D, Lyubimov, A.Y, Ogata, C.M, Uervirojnangkoorn, M, Brunger, A.T, Berger, J.M. | Deposit date: | 2015-04-10 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A high-transparency, micro-patternable chip for X-ray diffraction analysis of microcrystals under native growth conditions. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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