7ZFX

VDR complex with Aromatic-D-Ring Analog

Summary for 7ZFX

• Entry DOI: 10.2210/pdb7zfx/pdb
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 1, ACETATE ION, ... (5 entities in total)
• Functional Keywords: complex, agonist, vitamin d receptor, transcription
• Biological source: Danio rerio (zebrafish); More
• Total number of polymer chains: 2
• Total formula weight: 36394.53

Authors

Rochel, N. (deposition date: 2022-04-01, release date: 2022-11-23, Last modification date: 2024-01-31)

• Primary citation: Seoane, S.,Gogoi, P.,Zarate-Ruiz, A.,Peluso-Iltis, C.,Peters, S.,Guiberteau, T.,Maestro, M.A.,Perez-Fernandez, R.,Rochel, N.,Mourino, A.; Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3.; J.Med.Chem., 65:13112-13124, 2022; PubMed: 36166643; DOI: 10.1021/acs.jmedchem.2c00900

Experimental method

X-RAY DIFFRACTION (2.6 Å)