7W8O
 
 | |
7YY4
 | |
7YYA
 | |
7W8K
 | |
7W8R
 | |
7Z62
 | | Structure of the LecA lectin from Pseudomonas aeruginosa in complex with a biaryl-thiogalactoside | | Descriptor: | (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[4-[1-(4-methoxyphenyl)ethenyl]phenyl]sulfanyl-oxane-3,4,5-triol, 1,2-ETHANEDIOL, CALCIUM ION, ... | | Authors: | Varrot, A. | | Deposit date: | 2022-03-10 | | Release date: | 2023-01-18 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties.
Eur.J.Med.Chem., 247, 2022
|
|
7Z63
 | |
2HR7
 | | Insulin receptor (domains 1-3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Garrett, T.P.J, Ward, C.W. | | Deposit date: | 2006-07-19 | | Release date: | 2006-08-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
7WE3
 | |
7WEI
 | |
6MV6
 | | Crystal structure of RNAse 6 | | Descriptor: | PHOSPHATE ION, Ribonuclease K6 | | Authors: | Couture, J.-F, Doucet, N. | | Deposit date: | 2018-10-24 | | Release date: | 2019-11-13 | | Last modified: | 2020-05-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Insights into Structural and Dynamical Changes Experienced by Human RNase 6 upon Ligand Binding.
Biochemistry, 59, 2020
|
|
7E6J
 | | Aspartyl/Asparaginyl beta-hydroxylase (AspH) H725A in complex with Factor X peptide fragment (39mer-4Ser) | | Descriptor: | Aspartyl/asparaginyl beta-hydroxylase, GLYCEROL, PROPANOIC ACID, ... | | Authors: | Nakashima, Y, Brasnett, A, Brewitz, L, Schofield, C.J. | | Deposit date: | 2021-02-22 | | Release date: | 2021-06-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Human Oxygenase Variants Employing a Single Protein Fe II Ligand Are Catalytically Active.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
1SR7
 | | Progesterone Receptor Hormone Binding Domain with Bound Mometasone Furoate | | Descriptor: | GLYCEROL, MOMETASONE FUROATE, Progesterone receptor, ... | | Authors: | Madauss, K.P, Deng, S.-J, Austin, R.J, Lambert, M.H, McLay, I, Pritchard, J, Short, S.A, Stewart, E.L, Uings, I.J, Williams, S.P. | | Deposit date: | 2004-03-22 | | Release date: | 2004-06-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes
J.Med.Chem., 47, 2004
|
|
6MW8
 | | UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Manganese | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... | | Authors: | Kim, H.W, Wood, Z.A, West, C.M. | | Deposit date: | 2018-10-29 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.756 Å) | | Cite: | A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
|
|
1H2R
 | |
6MV7
 | | Crystal structure of RNAse 6 | | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribonuclease K6 | | Authors: | Couture, J.-F, Doucet, N. | | Deposit date: | 2018-10-24 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Insights into Structural and Dynamical Changes Experienced by Human RNase 6 upon Ligand Binding.
Biochemistry, 59, 2020
|
|
4KYO
 | | Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human Pex5p | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, Peroxisomal targeting signal 1 receptor, ... | | Authors: | Fodor, K, Lou, Y, Wilmanns, M. | | Deposit date: | 2013-05-29 | | Release date: | 2014-11-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes.
Traffic, 16, 2015
|
|
4O6Q
 | | 0.95A resolution structure of the hemophore HasA from Pseudomonas aeruginosa (Y75A mutant) | | Descriptor: | FORMIC ACID, HasAp, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Lovell, S, Kumar, R, Battaile, K.P, Matsumura, H, Yao, H, Rodriguez, J.C, Moenne-Loccoz, P, Rivera, M. | | Deposit date: | 2013-12-23 | | Release date: | 2014-03-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa.
Biochemistry, 53, 2014
|
|
3IFB
 | | NMR STUDY OF HUMAN INTESTINAL FATTY ACID BINDING PROTEIN | | Descriptor: | INTESTINAL FATTY ACID BINDING PROTEIN | | Authors: | Zhang, F, Luecke, C, Baier, L.J, Sacchettini, J.C, Hamilton, J.A. | | Deposit date: | 1998-10-16 | | Release date: | 1998-10-21 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit.
J.Biomol.NMR, 9, 1997
|
|
5FJV
 | | Crystal structure of the extracellular domain of alpha2 nicotinic acetylcholine receptor in pentameric assembly | | Descriptor: | EPIBATIDINE, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 | | Authors: | Giastas, P, Kouvatsos, N, Chroni-Tzartou, D, Tzartos, S.J. | | Deposit date: | 2015-10-13 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal Structure of a Human Neuronal Nachr Extracellular Domain in Pentameric Assembly: Ligand-Bound Alpah2 Homopentamer.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
1GWF
 | | Compound II structure of Micrococcus Lysodeikticus catalase | | Descriptor: | ACETATE ION, Catalase, OXYGEN ATOM, ... | | Authors: | Murshudov, G.N, Grebenko, A.I, Brannigan, J.A, Antson, A.A, Barynin, V.V, Dodson, G.G, Dauter, Z, Wilson, K.S, Melik-Adamyan, W.R. | | Deposit date: | 2002-03-15 | | Release date: | 2002-04-26 | | Last modified: | 2018-06-20 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex.
Acta Crystallogr.,Sect.D, 58, 2002
|
|
2JN3
 | | NMR structure of cl-BABP complexed to chenodeoxycholic acid | | Descriptor: | CHENODEOXYCHOLIC ACID, Fatty acid-binding protein, liver | | Authors: | Eliseo, T, Ragona, L, Catalano, M, Assfalf, M, Paci, M, Zetta, L, Molinari, H, Cicero, D.O. | | Deposit date: | 2006-12-22 | | Release date: | 2007-07-03 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR
Biochemistry, 46, 2007
|
|
5DDB
 | | Menin in complex with MI-319 | | Descriptor: | 4-{4-[5-(difluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | Authors: | Pollock, J, Dmitry, B, Cierpicki, T, Grembecka, J. | | Deposit date: | 2015-08-24 | | Release date: | 2015-09-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand Complexes.
J.Med.Chem., 58, 2015
|
|
6FSH
 | | Crystal structure of hybrid P450 OxyBtei(BC/FGvan) | | Descriptor: | ACETATE ION, OxyB protein, POTASSIUM ION, ... | | Authors: | Brieke, C, Tarnawski, M, Greule, A, Cryle, M.J. | | Deposit date: | 2018-02-19 | | Release date: | 2018-05-23 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach.
J. Inorg. Biochem., 185, 2018
|
|
1O9I
 | | Crystal structure of the Y42F mutant of manganese catalase from Lactobacillus plantarum at 1.33A resolution | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, MANGANESE (III) ION, ... | | Authors: | Barynin, V.V, Whittaker, M.M, Whittaker, J.W. | | Deposit date: | 2002-12-13 | | Release date: | 2003-12-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Outer Sphere Mutagenesis of Lactobacillus Plantarum Manganese Catalase Disrupts the Cluster Core. Mechanistic Implications.
Eur.J.Biochem., 270, 2003
|
|
