6D6E
 
 | | Triclinic lysozyme (295 K) in the presence of 47% xylose | | Descriptor: | Lysozyme C, NITRATE ION | | Authors: | Juers, D.H. | | Deposit date: | 2018-04-20 | | Release date: | 2018-09-19 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018
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6D6F
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1NYJ
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6D6G
 | | Triclinic lysozyme (295 K) in the presence of 47% MPD | | Descriptor: | Lysozyme C, NITRATE ION | | Authors: | Juers, D.H. | | Deposit date: | 2018-04-20 | | Release date: | 2018-09-19 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Acta Crystallogr D Struct Biol, 74, 2018
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5J0M
 | | Ground state sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat | | Descriptor: | Apical region (29-mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat | | Authors: | Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M. | | Deposit date: | 2016-03-28 | | Release date: | 2016-06-08 | | Last modified: | 2019-10-23 | | Method: | SOLUTION NMR | | Cite: | Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8Q92
 | | P301S Tau Filaments from the Brains of PS19 Transgenic Mouse Line | | Descriptor: | Microtubule-associated protein tau | | Authors: | Schweighauser, M, Murzin, A.G, Macdonald, J, Lavenir, I, Crowther, R.A, Scheres, S.H.W, Goedert, M. | | Deposit date: | 2023-08-19 | | Release date: | 2023-10-11 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Acta Neuropathol Commun, 11, 2023
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6T22
 | | N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5hmCGA target sequence | | Descriptor: | DNA (5'-D(*GP*AP*AP*TP*(5HC)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5HC)P*GP*AP*TP*TP*C)-3'), EcoKMcrA modification dependent restriction endonuclease | | Authors: | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | | Deposit date: | 2019-10-07 | | Release date: | 2019-10-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
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5P2P
 | | X-RAY STRUCTURE OF PHOSPHOLIPASE A2 COMPLEXED WITH A SUBSTRATE-DERIVED INHIBITOR | | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2, PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER | | Authors: | Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J. | | Deposit date: | 1990-09-01 | | Release date: | 1991-10-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor.
Nature, 347, 1990
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6T21
 | | N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5mCGA target sequence | | Descriptor: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*TP*(5CM)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5CM)P*GP*AP*TP*TP*C)-3') | | Authors: | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | | Deposit date: | 2019-10-07 | | Release date: | 2019-10-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
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1NQP
 | | Crystal structure of Human hemoglobin E at 1.73 A resolution | | Descriptor: | CYANIDE ION, Hemoglobin alpha chain, Hemoglobin beta chain, ... | | Authors: | Dasgupta, J, Sen, U, Choudhury, D, Dutta, P, Basu, S, Chakrabarti, A, Chakrabarty, A, Dattagupta, J.K. | | Deposit date: | 2003-01-22 | | Release date: | 2004-03-02 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Crystallization and preliminary X-ray structural Studies of Hemoglobin A2 and Hemoglobin E, isolated from the blood samples of Beta-thalassemic patients
Biochem.Biophys.Res.Commun., 303, 2004
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2J3V
 | | Crystal structure of the enzymatic component C2-I of the C2-toxin from Clostridium botulinum at pH 3.0 | | Descriptor: | C2 TOXIN COMPONENT I, GLYCEROL, SULFATE ION | | Authors: | Schleberger, C, Hochmann, H, Barth, H, Aktories, K, Schulz, G.E. | | Deposit date: | 2006-08-23 | | Release date: | 2006-10-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structure and Action of the Binary C2 Toxin from Clostridium Botulinum.
J.Mol.Biol., 364, 2006
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5J1O
 | | Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat | | Descriptor: | Apical region (29mer) of the HIV-1 TAR element, Cyclic peptide mimetic of Tat | | Authors: | Borkar, A.N, Bardaro, M.F, Varani, G, Vendruscolo, M. | | Deposit date: | 2016-03-29 | | Release date: | 2016-06-08 | | Last modified: | 2019-10-23 | | Method: | SOLUTION NMR | | Cite: | Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7FC0
 | | Reconstitution of MbnABC complex from Rugamonas rubra ATCC-43154 (GroupIII) | | Descriptor: | FE (III) ION, Methanobactin biosynthesis cassette protein MbnB, Methanobactin biosynthesis cassette protein MbnC, ... | | Authors: | Chao, D, Zhaolin, L, Shoujie, L, Li, Z, Dan, Z, Ying, J, Wei, C. | | Deposit date: | 2021-07-13 | | Release date: | 2022-03-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.643 Å) | | Cite: | Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis.
Cell Res., 32, 2022
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1NTF
 | | Crystal Structure of Cimex Nitrophorin | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, salivary nitrophorin | | Authors: | Weichsel, A, Maes, E.M, Andersen, J.F, Valenzuela, J.G, Walker, F.A, Montfort, W.R. | | Deposit date: | 2003-01-29 | | Release date: | 2004-03-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein.
Proc.Natl.Acad.Sci.USA, 102, 2005
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2IVD
 | | Structure of protoporphyrinogen oxidase from Myxococcus xanthus with acifluorfen | | Descriptor: | (3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Corradi, H.R, Corrigall, A.V, Boix, E, Mohan, C.G, Sturrock, E.D, Meissner, P.N, Acharya, K.R. | | Deposit date: | 2006-06-12 | | Release date: | 2006-10-17 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus Xanthus and its Complex with the Inhibitor Acifluorfen.
J.Biol.Chem., 281, 2006
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8Q72
 | | E. coli plasmid-borne JetABCD(E248A) core in a cleavage-competent state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Circular plasmid DNA (1840-MER), JetA, ... | | Authors: | Roisne-Hamelin, F, Li, Y, Gruber, S. | | Deposit date: | 2023-08-15 | | Release date: | 2024-01-31 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.17 Å) | | Cite: | Structural basis for plasmid restriction by SMC JET nuclease.
Mol.Cell, 84, 2024
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6T5F
 | | Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-195 | | Descriptor: | 14-3-3 protein sigma, StARD1 peptide | | Authors: | Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. | | Deposit date: | 2019-10-16 | | Release date: | 2020-11-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family.
Febs J., 287, 2020
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8QFD
 | | UFL1 E3 ligase bound 60S ribosome | | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Makhlouf, L, Kulathu, Y, Zeqiraj, E. | | Deposit date: | 2023-09-04 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Nature, 627, 2024
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8R4Q
 | | Salt inducible kinase 3 in complex with inhibitor | | Descriptor: | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, SULFATE ION, Serine/threonine-protein kinase SIK3, ... | | Authors: | Kack, H, Oster, L. | | Deposit date: | 2023-11-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.838 Å) | | Cite: | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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8R4V
 | | Structure of Salt-inducible kinase 3 in complex with inhibitor | | Descriptor: | 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]urea, Serine/threonine-protein kinase SIK3 | | Authors: | Kack, H, Oster, L. | | Deposit date: | 2023-11-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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6DIK
 | | Crystal structure of Bothropstoxin I (BthTX-I) complexed to Chicoric acid | | Descriptor: | (2R,3R)-2,3-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}butanedioic acid, BICARBONATE ION, Basic phospholipase A2 homolog bothropstoxin-1, ... | | Authors: | Cardoso, F.F, Salvador, G.H.M, Borges, R.J. | | Deposit date: | 2018-05-23 | | Release date: | 2018-10-03 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins.
Biochim Biophys Acta Gen Subj, 1862, 2018
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8R4U
 | | Structure of salt-inducible kinase 3 with inhibitors | | Descriptor: | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one, SULFATE ION, Serine/threonine-protein kinase SIK3, ... | | Authors: | Kack, H, Oster, L. | | Deposit date: | 2023-11-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.416 Å) | | Cite: | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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8R4O
 | | Salt inducible kinase 3 in complex with inhibitor | | Descriptor: | 2-[bis(fluoranyl)methoxy]-4-[6-(2-cyanopropan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]-~{N}-[(1~{R},2~{S})-2-fluoranylcyclopropyl]-6-methoxy-benzamide, SULFATE ION, Serine/threonine-protein kinase SIK3, ... | | Authors: | Kack, H, Oster, L. | | Deposit date: | 2023-11-14 | | Release date: | 2024-03-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.725 Å) | | Cite: | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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5M5R
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5J6T
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