6T22
N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5hmCGA target sequence
Summary for 6T22
Entry DOI | 10.2210/pdb6t22/pdb |
Related | 6GHC 6R64 6T21 |
Descriptor | EcoKMcrA modification dependent restriction endonuclease, DNA (5'-D(*TP*CP*AP*TP*(5HC)P*GP*AP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*TP*(5HC)P*GP*AP*TP*GP*A)-3'), ... (4 entities in total) |
Functional Keywords | ecokmcra, neco, n-terminal domain, modification dependent restriction, 5-methylcytosine, 5mc, 5-hydroxymethylcytosine, 5hmc, hnh endonuclease, bba-me nuclease, hydrolase |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 6 |
Total formula weight | 47033.38 |
Authors | Slyvka, A.,Zagorskaite, E.,Czapinska, H.,Sasnauskas, G.,Bochtler, M. (deposition date: 2019-10-07, release date: 2019-10-30, Last modification date: 2024-01-24) |
Primary citation | Slyvka, A.,Zagorskaite, E.,Czapinska, H.,Sasnauskas, G.,Bochtler, M. Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping. Nucleic Acids Res., 47:11943-11955, 2019 Cited by PubMed: 31724709DOI: 10.1093/nar/gkz1017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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