7R03
 
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5CJ0
 | | Crystal Structure of Amino Acids 1631-1692 of MYH7 | | Descriptor: | Xrcc4-MYH7-(1631-1692) chimera protein | | Authors: | Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I. | | Deposit date: | 2015-07-13 | | Release date: | 2015-12-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
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7R24
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7R5K
 | | Human nuclear pore complex (constricted) | | Descriptor: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | Authors: | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | Deposit date: | 2022-02-10 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | AI-based structure prediction empowers integrative structural analysis of human nuclear pores.
Science, 376, 2022
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4BC4
 | | Crystal structure of human D-xylulokinase in complex with D-xylulose | | Descriptor: | 1,2-ETHANEDIOL, D-XYLULOSE, XYLULOSE KINASE | | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | | Deposit date: | 2012-10-01 | | Release date: | 2012-11-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
J.Biol.Chem., 288, 2013
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5CJ1
 | | Crystal structure of the coiled coil of MYH7 residues 1526 to 1571 fused to Gp7 | | Descriptor: | Gp7-MYH7-(1526-1571) chimera protein | | Authors: | Taylor, K.C, Korkmaz, E.N, Andreas, M.P, Ajay, G, Heinz, N.T, Cui, Q, Rayment, I. | | Deposit date: | 2015-07-13 | | Release date: | 2015-12-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
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7R5J
 | | Human nuclear pore complex (dilated) | | Descriptor: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | Authors: | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | Deposit date: | 2022-02-10 | | Release date: | 2022-09-21 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (50 Å) | | Cite: | AI-based structure prediction empowers integrative structural analysis of human nuclear pores
Science, 376, 2022
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7R4H
 | | phospho-STING binding to adaptor protein complex-1 | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Xu, P, Ablasser, A. | | Deposit date: | 2022-02-08 | | Release date: | 2022-09-14 | | Last modified: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (2.34 Å) | | Cite: | Clathrin-associated AP-1 controls termination of STING signalling.
Nature, 610, 2022
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5CIW
 | | Ran GDP Y39A mutant monoclinic crystal form | | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Vetter, I.R, Brucker, S. | | Deposit date: | 2015-07-13 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
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5CIQ
 | | Ran GDP wild type tetragonal crystal form | | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Vetter, I.R, Brucker, S. | | Deposit date: | 2015-07-13 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
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5CIT
 | | Ran GDP wild type monoclinic crystal form | | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Vetter, I.R, Brucker, S. | | Deposit date: | 2015-07-13 | | Release date: | 2015-09-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
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5CJ4
 | | Crystal Structure of Amino Acids 1562-1622 of MYH7 | | Descriptor: | Xrcc4-MYH7-(1562-1622) chimera protein | | Authors: | Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I. | | Deposit date: | 2015-07-13 | | Release date: | 2015-12-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.102 Å) | | Cite: | A composite approach towards a complete model of the myosin rod.
Proteins, 84, 2016
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4BG6
 | | 14-3-3 interaction with Rnd3 prenyl-phosphorylation motif | | Descriptor: | 14-3-3 PROTEIN ZETA/DELTA, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FARNESYL, ... | | Authors: | Riou, P, Kjaer, S, Purkiss, A, O'Reilly, N, McDonald, N.Q. | | Deposit date: | 2013-03-23 | | Release date: | 2013-05-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | 14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins.
Cell(Cambridge,Mass.), 153, 2013
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5DHF
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2IX7
 | | Structure of apo-calmodulin bound to unconventional myosin V | | Descriptor: | CALMODULIN, CYSTEINE, MYOSIN-5A, ... | | Authors: | Houdusse, A, Gaucher, J.F, Mui, S, Krementsova, E, Trybus, K.M, Cohen, C. | | Deposit date: | 2006-07-07 | | Release date: | 2006-12-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of Apo-Calmodulin Bound to the First Two Iq Motifs of Myosin V Reveals Essential Recognition Features.
Proc.Natl.Acad.Sci.USA, 103, 2006
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4AU8
 | | Crystal structure of compound 4a in complex with cdk5, showing an unusual binding mode to the hinge region via a water molecule | | Descriptor: | 4-(1,3-benzothiazol-2-yl)thiophene-2-sulfonamide, CYCLIN-DEPENDENT KINASE 5, IMIDAZOLE, ... | | Authors: | Malmstrom, J, Viklund, J, Slivo, C, Costa, A, Maudet, M, Sandelin, C, Hiller, G, Olsson, L.L, Aagaard, A, Geschwindner, S, Xue, Y, Vasange, M. | | Deposit date: | 2012-05-14 | | Release date: | 2013-03-27 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Synthesis and Structure-Activity Relationship of 4-(1,3-Benzothiazol-2-Yl)-Thiophene-2-Sulfonamides as Cyclin-Dependent Kinase 5 (Cdk5)/P25 Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
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4BC5
 | | Crystal structure of human D-xylulokinase in complex with inhibitor 5- deoxy-5-fluoro-D-xylulose | | Descriptor: | 1,2-ETHANEDIOL, 5-deoxy-5-fluoro-D-xylulose, XYLULOSE KINASE | | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | | Deposit date: | 2012-10-01 | | Release date: | 2012-11-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
J.Biol.Chem., 288, 2013
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7ROV
 | | KRAS G12D Mutant in complex with GMPPCP and cyclic peptide MP-9903 | | Descriptor: | Cyclic peptide MP-9903, GLYCEROL, Isoform 2B of GTPase KRas, ... | | Authors: | Orth, P. | | Deposit date: | 2021-08-02 | | Release date: | 2021-09-22 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.
Chem Sci, 12, 2021
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7RSC
 | | NMR-driven structure of the KRAS4B-G12D "alpha-alpha" dimer on a lipid bilayer nanodisc | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, GTPase KRas, ... | | Authors: | Lee, K, Enomoto, M, Gebregiworgis, T, Gasmi-Seabrook, G.M, Ikura, M, Marshall, C.B. | | Deposit date: | 2021-08-11 | | Release date: | 2021-09-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization.
Chem Sci, 12, 2021
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7RSE
 | | NMR-driven structure of the KRAS4B-G12D "alpha-beta" dimer on a lipid bilayer nanodisc | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, GTPase KRas, ... | | Authors: | Lee, K, Enomoto, M, Gebregiworgis, T, Gasmi-Seabrook, G.M, Ikura, M, Marshall, C.B. | | Deposit date: | 2021-08-11 | | Release date: | 2021-09-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization.
Chem Sci, 12, 2021
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5DH9
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2JT4
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4BGB
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5A18
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4BC3
 | | Crystal structure of human D-xylulokinase | | Descriptor: | 1,2-ETHANEDIOL, XYLULOSE KINASE | | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | | Deposit date: | 2012-10-01 | | Release date: | 2012-11-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
J.Biol.Chem., 288, 2013
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