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3VKZ
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BU of 3vkz by Molmil
3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at atmospheric pressure
Descriptor: 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, CALCIUM ION, ...
Authors:Nagae, T, Watanabe, N.
Deposit date:2011-11-28
Release date:2012-02-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:High-pressure-induced water penetration into 3-isopropylmalate dehydrogenase
Acta Crystallogr.,Sect.D, 68, 2012
4PXD
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BU of 4pxd by Molmil
The crystal structure of EcAAH in complex with allantoate
Descriptor: ALLANTOATE ION, Allantoate amidohydrolase, MANGANESE (II) ION
Authors:Shin, I, Rhee, S.
Deposit date:2014-03-23
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the substrate specificity of (s)-ureidoglycolate amidohydrolase and its comparison with allantoate amidohydrolase.
J.Mol.Biol., 426, 2014
3V8W
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BU of 3v8w by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 469
Descriptor: 3-[2-(5-phenyl-2H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
Authors:McLean, L.R, Zhang, Y.
Deposit date:2011-12-23
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
4PY2
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BU of 4py2 by Molmil
Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor 1-{3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}-3-THIOPHEN-3-YLUREA
Descriptor: 1,2-ETHANEDIOL, 1-{3-[(3,5-dichlorobenzyl)amino]propyl}-3-thiophen-3-ylurea, Methionine--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-03-25
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Plos One, 11, 2016
4PXC
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BU of 4pxc by Molmil
The crystal structure of AtUAH in complex with (S)-hydroxyglycine
Descriptor: (2S)-amino(hydroxy)ethanoic acid, MANGANESE (II) ION, Ureidoglycolate hydrolase
Authors:Shin, I, Rhee, S.
Deposit date:2014-03-23
Release date:2014-07-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.893 Å)
Cite:Structural insights into the substrate specificity of (s)-ureidoglycolate amidohydrolase and its comparison with allantoate amidohydrolase.
J.Mol.Biol., 426, 2014
3VM8
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BU of 3vm8 by Molmil
Crystal structure of the human APOBEC3C having HIV-1 Vif-binding interface
Descriptor: Probable DNA dC->dU-editing enzyme APOBEC-3C, ZINC ION
Authors:Kitamura, S, Suzuki, A, Watanabe, N, Iwatani, Y.
Deposit date:2011-12-09
Release date:2012-10-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the human APOBEC3C having HIV-1 Vif-binding interface
To be Published
3F2R
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BU of 3f2r by Molmil
Crystal structure of human choline kinase alpha in complex with hemicholinium-3
Descriptor: (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), Choline kinase alpha, UNKNOWN ATOM OR ION
Authors:Hong, B, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-10-30
Release date:2008-11-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of human choline kinase alpha in complex with hemicholinium-3
To be Published
3VAF
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BU of 3vaf by Molmil
Structure of U2AF65 variant with BrU3 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VOM
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BU of 3vom by Molmil
Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis
Descriptor: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, Putative phosphoserine aminotransferase, ...
Authors:Coulibaly, F, Lassalle, E, Baker, H.M, Baker, E.N.
Deposit date:2012-01-30
Release date:2012-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
4Q0E
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BU of 4q0e by Molmil
Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-L-glutamic acid.
Descriptor: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, N-{4-[(2-amino-4-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzoyl}-L-glutamic acid, ...
Authors:Kumar, V.P, Anderson, K.S.
Deposit date:2014-04-01
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.
Bioorg.Med.Chem.Lett., 24, 2014
3VAM
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BU of 3vam by Molmil
Structure of U2AF65 variant with BrU5C2 DNA
Descriptor: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ...
Authors:Jenkins, J.L, Kielkopf, C.L.
Deposit date:2011-12-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
3VPA
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BU of 3vpa by Molmil
Staphylococcus aureus FtsZ apo-form
Descriptor: Cell division protein FtsZ
Authors:Matsui, T, Yamane, J, Mogi, N, Yao, M, Tanaka, I.
Deposit date:2012-02-28
Release date:2012-08-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.487 Å)
Cite:Structural reorganization of the bacterial cell-division protein FtsZ from Staphylococcus aureus
Acta Crystallogr.,Sect.D, 68, 2012
3F5T
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BU of 3f5t by Molmil
X-ray Structure of H5N1 NS1
Descriptor: Nonstructural protein 1
Authors:Bornholdt, Z.A, Prasad, B.V.V.
Deposit date:2008-11-04
Release date:2008-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
Nature, 456, 2008
3FMA
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BU of 3fma by Molmil
Crystal structure of the GYF domain of Smy2 in complex with a proline-rich peptide from BBP/ScSF1
Descriptor: Branchpoint-bridging protein, Protein SMY2
Authors:Ash, M.R, Faelber, K.
Deposit date:2008-12-19
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:SMY2-type GYF domain recognition in mRNA surveillance complexes
to be published
3F61
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BU of 3f61 by Molmil
Crystal Structure of M. tuberculosis PknB Leu33Asp/Val222Asp double mutant in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase pknB
Authors:Mieczkowski, C.A, Alber, T, TB Structural Genomics Consortium (TBSGC)
Deposit date:2008-11-05
Release date:2008-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase.
Embo J., 27, 2008
3F69
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BU of 3f69 by Molmil
Crystal structure of the Mycobacterium tuberculosis PknB mutant kinase domain in complex with KT5720
Descriptor: SULFATE ION, Serine/threonine-protein kinase pknB, hexyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8-tetrahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]c yclopenta[e]-as-indacene-6-carboxylate
Authors:Alber, T, Mieczkowski, C.A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2008-11-05
Release date:2008-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase.
Embo J., 27, 2008
3FMS
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BU of 3fms by Molmil
Crystal structure of TM0439, a GntR transcriptional regulator
Descriptor: ACETATE ION, NICKEL (II) ION, Transcriptional regulator, ...
Authors:Zheng, M, Cooper, D.R, Yu, M, Hung, L.-W, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2008-12-22
Release date:2009-02-10
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
3VC3
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BU of 3vc3 by Molmil
Crystal structure of beta-cyanoalanine synthase K95A mutant in soybean
Descriptor: N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE, beta-cyanoalnine synthase
Authors:Yi, H, Jez, J.M.
Deposit date:2012-01-03
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.766 Å)
Cite:Structure of Soybean beta-Cyanoalanine Synthase and the Molecular Basis for Cyanide Detoxification in Plants.
Plant Cell, 24, 2012
3F72
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BU of 3f72 by Molmil
Crystal Structure of the Staphylococcus aureus pI258 CadC Metal Binding Site 2 Mutant
Descriptor: Cadmium efflux system accessory protein, SODIUM ION
Authors:Kandegedara, A, Thiyagarajan, S, Kondapalli, K.C, Stemmler, T.L, Rosen, B.P.
Deposit date:2008-11-07
Release date:2009-04-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Role of bound Zn(II) in the CadC Cd(II)/Pb(II)/Zn(II)-responsive repressor.
J.Biol.Chem., 284, 2009
3VT1
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BU of 3vt1 by Molmil
Crystal structure of Ct1,3Gal43A in complex with galactose
Descriptor: Ricin B lectin, beta-D-galactopyranose
Authors:Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C.
Deposit date:2012-05-18
Release date:2012-12-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.187 Å)
Cite:Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum
J.Struct.Biol., 180, 2012
4Q2O
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BU of 4q2o by Molmil
PDLIM4 PDZ in Complex with a Phage-Derived Peptide
Descriptor: PDZ and LIM domain protein 4
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2014-04-09
Release date:2014-09-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural portrait of the PDZ domain family.
J.Mol.Biol., 426, 2014
4Q2Y
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BU of 4q2y by Molmil
Crystal structure of Arginyl-tRNA synthetase
Descriptor: Arginine--tRNA ligase, cytoplasmic
Authors:Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y.
Deposit date:2014-04-10
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:The crystal structure of arginyl-tRNA synthetase from Homo sapiens
Febs Lett., 588, 2014
3FOR
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BU of 3for by Molmil
Thermolysin Complexed with BNPA (2-Benzyl-3-Nitro Propanoic Acid Amide)
Descriptor: (2R)-2-benzyl-3-nitropropanamide, CALCIUM ION, DIMETHYL SULFOXIDE, ...
Authors:Wang, S.-F, Jin, J.-Y, Tian, G.-R.
Deposit date:2008-12-31
Release date:2010-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Nitro as ZBG in the inhibition of Thermolysin
To be Published
3VEZ
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BU of 3vez by Molmil
Crystal structure of the O-carbamoyltransferase TobZ K443A variant in complex with ATP, ADP and carbamoyl phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, FE (II) ION, ...
Authors:Parthier, C, Stubbs, M.T, Goerlich, S, Jaenecke, F.
Deposit date:2012-01-09
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.
Angew.Chem.Int.Ed.Engl., 51, 2012
3FI8
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BU of 3fi8 by Molmil
Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Choline kinase, MAGNESIUM ION, ...
Authors:Wernimont, A.K, Pizarro, J.C, Artz, J.D, Amaya, M.F, Xiao, T, Lew, J, Wasney, G, Senesterra, G, Kozieradzki, I, Cossar, D, Vedadi, M, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
Deposit date:2008-12-11
Release date:2009-02-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020
TO BE PUBLISHED

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數據於2024-07-10公開中

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