3F61

Crystal Structure of M. tuberculosis PknB Leu33Asp/Val222Asp double mutant in complex with ADP

Summary for 3F61

Entry DOI	10.2210/pdb3f61/pdb
Descriptor	Serine/threonine-protein kinase pknB, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	protein kinase, pknb, mycobacterium tuberculosis, structural genomics, pknb kd double mutant bound to adp, tb structural genomics consortium, tbsgc, atp-binding, kinase, magnesium, metal-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	34060.98
Authors	Mieczkowski, C.A.,Alber, T.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2008-11-05, release date: 2008-12-02, Last modification date: 2024-04-03)
Primary citation	Mieczkowski, C.,Iavarone, A.T.,Alber, T. Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase. Embo J., 27:3186-3197, 2008 Cited by PubMed: 19008858 DOI: 10.1038/emboj.2008.236 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation