3VEZ

Crystal structure of the O-carbamoyltransferase TobZ K443A variant in complex with ATP, ADP and carbamoyl phosphate

Summary for 3VEZ

• Entry DOI: 10.2210/pdb3vez/pdb
• Related: 3VEN 3VEO 3VER 3VES 3VET 3VEW 3VEX 3VF2 3VF4
• Descriptor: O-carbamoyltransferase TobZ, FE (II) ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: antibiotic biosynthesis, substrate assisted catalysis, substrate channeling, adenylation, structural enzymology, enzyme evolution, transferase
• Biological source: Streptoalloteichus tenebrarius (Streptomyces tenebrarius)
• Total number of polymer chains: 1
• Total formula weight: 64587.71

Authors

Parthier, C.,Stubbs, M.T.,Goerlich, S.,Jaenecke, F. (deposition date: 2012-01-09, release date: 2012-01-25, Last modification date: 2023-09-13)

• Primary citation: Parthier, C.,Gorlich, S.,Jaenecke, F.,Breithaupt, C.,Brauer, U.,Fandrich, U.,Clausnitzer, D.,Wehmeier, U.F.,Bottcher, C.,Scheel, D.,Stubbs, M.T.; The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.; Angew.Chem.Int.Ed.Engl., 51:4046-4052, 2012; PubMed: 22383337; DOI: 10.1002/anie.201108896

Experimental method

X-RAY DIFFRACTION (2.4 Å)