3VES

Crystal structure of the O-carbamoyltransferase TobZ in complex with AMPCPP and carbamoyl phosphate

Summary for 3VES

Entry DOI	10.2210/pdb3ves/pdb
Related	3VEN 3VEO 3VER 3VET 3VEW 3VEX 3VEZ 3VF2 3VF4
Descriptor	O-carbamoyltransferase TobZ, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (8 entities in total)
Functional Keywords	antibiotic biosynthesis, substrate assisted catalysis, substrate channeling, adenylation, structural enzymology, enzyme evolution, transferase
Biological source	Streptoalloteichus tenebrarius (Streptomyces tenebrarius)
Total number of polymer chains	1
Total formula weight	64275.32
Authors	Parthier, C.,Stubbs, M.T.,Goerlich, S.,Jaenecke, F. (deposition date: 2012-01-09, release date: 2012-01-25, Last modification date: 2023-09-13)
Primary citation	Parthier, C.,Gorlich, S.,Jaenecke, F.,Breithaupt, C.,Brauer, U.,Fandrich, U.,Clausnitzer, D.,Wehmeier, U.F.,Bottcher, C.,Scheel, D.,Stubbs, M.T. The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction. Angew.Chem.Int.Ed.Engl., 51:4046-4052, 2012 Cited by PubMed: 22383337 DOI: 10.1002/anie.201108896 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation