7MUE
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![BU of 7mue by Molmil](/molmil-images/mine/7mue) | Legionella pneumophila Dot/Icm T4SS PR | Descriptor: | DotF, IcmE protein, Type IV secretion protein IcmK, ... | Authors: | Sheedlo, M.J, Durie, C.L, Swanson, M, Lacy, D.B, Ohi, M.D. | Deposit date: | 2021-05-14 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS. Elife, 10, 2021
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8B6V
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![BU of 8b6v by Molmil](/molmil-images/mine/8b6v) | Mp2Ba1 pre-pore | Descriptor: | MAGNESIUM ION, Mpf2Ba1 | Authors: | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | Deposit date: | 2022-09-27 | Release date: | 2023-05-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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7M2M
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![BU of 7m2m by Molmil](/molmil-images/mine/7m2m) | NMR Structure of GCAP5 | Descriptor: | Guanylate cyclase activator 1A, MAGNESIUM ION | Authors: | Ames, J.B, Cudia, D.L. | Deposit date: | 2021-03-17 | Release date: | 2021-10-20 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | NMR and EPR-DEER Structure of a Dimeric Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors. Biochemistry, 60, 2021
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8BCS
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![BU of 8bcs by Molmil](/molmil-images/mine/8bcs) | X-ray crystal structure of a de novo designed helix-loop-helix homodimer in an anti arrangement, CC-HP1.0 | Descriptor: | ACETATE ION, CC-HP1.0 | Authors: | Edgell, C.L, Mylemans, B, Naudin, E.A, Smith, A.J, Savery, N.J, Woolfson, D.N. | Deposit date: | 2022-10-17 | Release date: | 2023-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology. Acs Synth Biol, 12, 2023
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7MSJ
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![BU of 7msj by Molmil](/molmil-images/mine/7msj) | The crystal structure of mouse HVEM | Descriptor: | SULFATE ION, Tumor necrosis factor receptor superfamily member 14 | Authors: | Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C. | Deposit date: | 2021-05-11 | Release date: | 2021-10-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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4V41
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![BU of 4v41 by Molmil](/molmil-images/mine/4v41) | E. COLI (LAC Z) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-MONOCLINIC) | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | Deposit date: | 2000-06-07 | Release date: | 2014-07-09 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
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6D9I
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![BU of 6d9i by Molmil](/molmil-images/mine/6d9i) | |
8BI2
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![BU of 8bi2 by Molmil](/molmil-images/mine/8bi2) | Syk kinase domain in complex with macrocyclic inhibitor 20a | Descriptor: | 10,13,23-trimethyl-16-oxa-2,4,8,9,13,19,23,30-octazapentacyclo[19.5.2.1^{3,7}.1^{8,11}.0^{24,28}]triaconta-1(27),3,5,7(30),9,11(29),21,24(28),25-nonaen-20-one, Tyrosine-protein kinase SYK | Authors: | Read, J.A, Patel, J. | Deposit date: | 2022-11-01 | Release date: | 2023-06-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.508 Å) | Cite: | Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors. Bioorg.Med.Chem.Lett., 91, 2023
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7MU1
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![BU of 7mu1 by Molmil](/molmil-images/mine/7mu1) | Thermotoga maritima encapsulin shell | Descriptor: | FLAVIN MONONUCLEOTIDE, Maritimacin | Authors: | LaFrance, B.J, Nogales, E, Savage, D.F. | Deposit date: | 2021-05-14 | Release date: | 2021-11-24 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The encapsulin from Thermotoga maritima is a flavoprotein with a symmetry matched ferritin-like cargo protein. Sci Rep, 11, 2021
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6DXX
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![BU of 6dxx by Molmil](/molmil-images/mine/6dxx) | Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL, ... | Authors: | Gorelik, A, Gebai, A, Illes, K, Piomelli, D, Nagar, B. | Deposit date: | 2018-07-01 | Release date: | 2018-09-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4V2Q
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![BU of 4v2q by Molmil](/molmil-images/mine/4v2q) | Ironing out their differences: Dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase | Descriptor: | PHENYLALANINE AMMONIA-LYASE | Authors: | Heberling, M, Masman, M, Bartsch, S, Wybenga, G.G, Dijkstra, B.W, Marrink, S, Janssen, D. | Deposit date: | 2014-10-14 | Release date: | 2014-12-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Ironing Out Their Differences: Dissecting the Structural Determinants of a Phenylalanine Aminomutase and Ammonia Lyase. Acs Chem.Biol., 10, 2015
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7MPZ
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6DLW
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![BU of 6dlw by Molmil](/molmil-images/mine/6dlw) | Complement component polyC9 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose | Authors: | Dunstone, M.A, Spicer, B.A, Law, R.H.P. | Deposit date: | 2018-06-03 | Release date: | 2018-09-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
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8BHW
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7MH3
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![BU of 7mh3 by Molmil](/molmil-images/mine/7mh3) | Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant; Y(M210)3-chlorotyrosine | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | Mathews, I, Weaver, J.B, Boxer, S.G. | Deposit date: | 2021-04-14 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Photosynthetic reaction center variants made via genetic code expansion show Tyr at M210 tunes the initial electron transfer mechanism. Proc.Natl.Acad.Sci.USA, 118, 2021
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2YHG
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![BU of 2yhg by Molmil](/molmil-images/mine/2yhg) | Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Hehemann, J.H, Marsters, C, Boraston, A.B. | Deposit date: | 2011-04-30 | Release date: | 2011-08-03 | Last modified: | 2018-06-13 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism. Proteins, 79, 2011
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8BDU
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![BU of 8bdu by Molmil](/molmil-images/mine/8bdu) | H33 variant of DoBi scaffold based on PIH1D1 N-terminal domain | Descriptor: | PIH1 domain-containing protein 1 | Authors: | Kolenko, P, Mikulecky, P, Pham, P.N, Schneider, B. | Deposit date: | 2022-10-20 | Release date: | 2023-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.471 Å) | Cite: | Diffraction anisotropy and paired refinement: crystal structure of H33, a protein binder to interleukin 10. J.Appl.Crystallogr., 56, 2023
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7MEE
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![BU of 7mee by Molmil](/molmil-images/mine/7mee) | CDD-1 beta-lactamase in imidazole/MPD 6 minute avibactam complex | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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7MEC
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![BU of 7mec by Molmil](/molmil-images/mine/7mec) | CDD-1 beta-lactamase in imidazole/MPD 4 minute avibactam complex | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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7MDJ
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![BU of 7mdj by Molmil](/molmil-images/mine/7mdj) | The structure of KcsA in complex with a synthetic Fab | Descriptor: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | Authors: | Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B. | Deposit date: | 2021-04-05 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels. J.Gen.Physiol., 154, 2022
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7MEF
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![BU of 7mef by Molmil](/molmil-images/mine/7mef) | CDD-1 beta-lactamase in imidazole/MPD 10 minute avibactam complex | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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7MEG
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![BU of 7meg by Molmil](/molmil-images/mine/7meg) | CDD-1 beta-lactamase in imidazole/MPD 30 minute avibactam complex | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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7ME9
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![BU of 7me9 by Molmil](/molmil-images/mine/7me9) | CDD-1 beta-lactamase in imidazole/MPD 30 seconds avibactam complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, SULFATE ION | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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7MEA
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![BU of 7mea by Molmil](/molmil-images/mine/7mea) | CDD-1 beta-lactamase in imidazole/MPD 1 minute avibactam complex | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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7MED
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![BU of 7med by Molmil](/molmil-images/mine/7med) | CDD-1 beta-lactamase in imidazole/MPD 5 minute avibactam complex | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | Authors: | Smith, C.A, Vakulenko, S.B. | Deposit date: | 2021-04-06 | Release date: | 2022-02-16 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7, 2021
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