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1TKY
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BU of 1tky by Molmil
Crystal structure of the editing domain of threonyl-tRNA synthetase complexed with seryl-3'-aminoadenosine
Descriptor: SERINE-3'-AMINOADENOSINE, Threonyl-tRNA synthetase
Authors:Dock-Bregeon, A.C, Rees, B, Torres-Larios, A, Bey, G, Caillet, J, Moras, D.
Deposit date:2004-06-09
Release date:2004-11-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Achieving Error-Free Translation; The Mechanism of Proofreading of Threonyl-tRNA Synthetase at Atomic Resolution.
Mol.Cell, 16, 2004
2ZCE
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BU of 2zce by Molmil
Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with pyrrolysine and an ATP analogue
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYRROLYSINE, ...
Authors:Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-11-08
Release date:2008-04-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase
J.Mol.Biol., 378, 2008
4HWO
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BU of 4hwo by Molmil
Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor
Descriptor: N-{[3-(4-aminoquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION
Authors:Hilgers, M.T.
Deposit date:2012-11-08
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.907 Å)
Cite:Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem., 56, 2013
4HWR
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BU of 4hwr by Molmil
Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor
Descriptor: N-{[3-(2H-indazol-5-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION
Authors:Hilgers, M.T.
Deposit date:2012-11-08
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem., 56, 2013
3BJU
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BU of 3bju by Molmil
Crystal Structure of tetrameric form of human lysyl-tRNA synthetase
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, LYSINE, ...
Authors:Guo, M, Yang, X.L, Schimmel, P.
Deposit date:2007-12-04
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
Proc.Natl.Acad.Sci.Usa, 105, 2008
4HWS
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BU of 4hws by Molmil
Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor
Descriptor: N-{[3-(4-amino-2-chloroquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION
Authors:Hilgers, M.T.
Deposit date:2012-11-08
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem., 56, 2013
4HWP
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BU of 4hwp by Molmil
Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor
Descriptor: N-{[3-(4-amino-2-methylquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION
Authors:Hilgers, M.T.
Deposit date:2012-11-08
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.807 Å)
Cite:Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem., 56, 2013
4HWT
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BU of 4hwt by Molmil
Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor
Descriptor: N-{[3-(2H-indazol-5-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, cytoplasmic, ...
Authors:Hilgers, M.T.
Deposit date:2012-11-08
Release date:2013-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem., 56, 2013
5UCM
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BU of 5ucm by Molmil
Crystal Structure of Prolyl-tRNA Synthetase from Pseudomonas aeruginosa
Descriptor: MAGNESIUM ION, Proline--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-12-22
Release date:2017-02-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Characterization and structure determination of prolyl-tRNA synthetase from Pseudomonas aeruginosa and development as a screening platform.
Protein Sci., 2019
2X1A
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BU of 2x1a by Molmil
Structure of Rna15 RRM with RNA bound (G)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2X1F
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BU of 2x1f by Molmil
Structure of Rna15 RRM with bound RNA (GU)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
5A17
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BU of 5a17 by Molmil
The structure of the SOLE element of oskar mRNA
Descriptor: OSKAR MRNA
Authors:Simon, B, Masiewicz, P, Ephrussi, A, Carlomagno, T.
Deposit date:2015-04-28
Release date:2015-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The Structure of the Sole Element of Oskar Mrna.
RNA, 21, 2015
5A18
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BU of 5a18 by Molmil
The structure of the SOLE element of oskar mRNA
Descriptor: OSKAR MRNA
Authors:Simon, B, Masiewicz, P, Ephrussi, A, Carlomagno, T.
Deposit date:2015-04-28
Release date:2015-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The Structure of the Sole Element of Oskar Mrna.
RNA, 21, 2015
3CJZ
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BU of 3cjz by Molmil
Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m22G:A pairs
Descriptor: RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3')
Authors:Pallan, P.S, Kreutz, C, Bosio, S, Micura, R, Egli, M.
Deposit date:2008-03-14
Release date:2008-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Rna, 14, 2008
6TNN
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BU of 6tnn by Molmil
Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA
Descriptor: 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C.
Deposit date:2019-12-09
Release date:2020-09-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Mol.Cell, 80, 2020
6FFR
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BU of 6ffr by Molmil
DNA-RNA Hybrid Quadruplex with Flipped Tetrad
Descriptor: DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3')
Authors:Haase, L, Dickerhoff, J, Weisz, K.
Deposit date:2018-01-09
Release date:2018-09-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies.
Chemistry, 24, 2018
3CZW
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BU of 3czw by Molmil
X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex
Descriptor: RNA (5'-R(*G*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3'), SULFATE ION
Authors:Rypniewski, W, Adamiak, D.A, Milecki, J, Adamiak, R.W.
Deposit date:2008-04-30
Release date:2008-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Noncanonical G(syn)-G(anti) base pairs stabilized by sulphate anions in two X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex.
Rna, 14, 2008
4V9I
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BU of 4v9i by Molmil
Crystal structure of thermus thermophilus 70S in complex with tRNAs and mRNA containing a pseudouridine in a stop codon
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S Ribosomal protein S10, ...
Authors:Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2014-07-09
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
1U7D
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BU of 1u7d by Molmil
crystal structure of apo M. jannashii tyrosyl-tRNA synthetase
Descriptor: Tyrosyl-tRNA synthetase
Authors:Zhang, Y, Wang, L, Schultz, P.G, Wilson, I.A.
Deposit date:2004-08-03
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine.
Protein Sci., 14, 2005
4V8Y
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BU of 4v8y by Molmil
Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex
Descriptor: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ...
Authors:Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
6LXD
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BU of 6lxd by Molmil
Pri-miRNA bound DROSHA-DGCR8 complex
Descriptor: Microprocessor complex subunit DGCR8, RNA (102-mer), Ribonuclease 3, ...
Authors:Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M.
Deposit date:2020-02-10
Release date:2020-04-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
6H67
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BU of 6h67 by Molmil
Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD)
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C.
Deposit date:2018-07-26
Release date:2018-08-29
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6H68
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BU of 6h68 by Molmil
Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with fully-ordered A49
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C.
Deposit date:2018-07-26
Release date:2018-08-29
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1ASY
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BU of 1asy by Molmil
CLASS II AMINOACYL TRANSFER RNA SYNTHETASES: CRYSTAL STRUCTURE OF YEAST ASPARTYL-TRNA SYNTHETASE COMPLEXED WITH TRNA ASP
Descriptor: ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER)
Authors:Ruff, M, Cavarelli, J, Rees, B, Krishnaswamy, S, Thierry, J.C, Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).
Science, 252, 1991
5SVA
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BU of 5sva by Molmil
Mediator-RNA Polymerase II Pre-Initiation Complex
Descriptor: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ...
Authors:Robinson, P.J, Bushnell, D.A, Kornberg, R.D.
Deposit date:2016-08-05
Release date:2016-09-28
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (15.3 Å)
Cite:Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016

238582

數據於2025-07-09公開中

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