8X1C
 
 | | Structure of nucleosome-bound SRCAP-C in the ADP-bound state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | | Deposit date: | 2023-11-06 | | Release date: | 2024-03-06 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
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8X15
 | | Structure of nucleosome-bound SRCAP-C in the apo state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y. | | Deposit date: | 2023-11-06 | | Release date: | 2024-03-06 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
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6FO1
 | | Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... | | Authors: | Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. | | Deposit date: | 2018-02-05 | | Release date: | 2018-04-04 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
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6IGM
 | | Cryo-EM Structure of Human SRCAP Complex | | Descriptor: | Actin-related protein 6, Helicase SRCAP, RuvB-like 1, ... | | Authors: | Feng, Y, Tian, Y, Wu, Z, Xu, Y. | | Deposit date: | 2018-09-25 | | Release date: | 2019-07-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-EM structure of human SRCAP complex.
Cell Res., 28, 2018
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2XSZ
 | | The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, RUVB-LIKE 1, RUVB-LIKE 2 | | Authors: | Gorynia, S, Bandeiras, T.M, Matias, P.M, Pinho, F.G, McVey, C.E, Vonrhein, C, Svergun, D.I, Round, A, Donner, P, Carrondo, M.A. | | Deposit date: | 2010-10-01 | | Release date: | 2011-10-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and Functional Insights Into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex.
J.Struct.Biol., 176, 2011
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9EMA
 | | RUVBL1/2 in complex with ATP and CB-6644 inhibitor | | Descriptor: | 5-chloranyl-2-ethoxy-4-fluoranyl-~{N}-[4-[[3-(methoxymethyl)-1-oxidanylidene-6,7-dihydro-5~{H}-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxidanylidene-butyl]benzamide, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Lopez-Perrote, A, Llorca, O, Garcia-Martin, C. | | Deposit date: | 2024-03-07 | | Release date: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Mechanism of allosteric inhibition of RUVBL1-RUVBL2 by the small-molecule CB-6644
Cell Rep Phys Sci, 2024
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9EMC
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4UF5
 | | Crystal structure of UCH-L5 in complex with inhibitory fragment of INO80G | | Descriptor: | NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 | | Authors: | Sahtoe, D.D, Van Dijk, W.J, El Oualid, F, Ekkebus, R, Ovaa, H, Sixma, T.K. | | Deposit date: | 2014-12-23 | | Release date: | 2015-03-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
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4UF6
 | | UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G | | Descriptor: | NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN, POLYUBIQUITIN-B, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 | | Authors: | Sahtoe, D.D, Van Dijk, W.J, El Oualid, F, Ekkebus, R, Ovaa, H, Sixma, T.K. | | Deposit date: | 2014-12-23 | | Release date: | 2015-03-04 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.69 Å) | | Cite: | Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
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3IHR
 | | Crystal Structure of Uch37 | | Descriptor: | FORMIC ACID, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | | Authors: | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2009-07-30 | | Release date: | 2009-08-11 | | Last modified: | 2023-07-26 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural characterization of human Uch37.
Proteins, 80, 2012
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7VDV
 | | The overall structure of human chromatin remodeling PBAF-nucleosome complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... | | Authors: | Chen, Z.C, Chen, K.J, Yuan, J.J. | | Deposit date: | 2021-09-07 | | Release date: | 2022-05-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
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6H7X
 | | First X-ray structure of full-length human RuvB-Like 2. | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | Authors: | Silva, S, Brito, J.A, Matias, P, Bandeiras, T. | | Deposit date: | 2018-07-31 | | Release date: | 2018-08-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.892 Å) | | Cite: | X-ray structure of full-length human RuvB-Like 2 - mechanistic insights into coupling between ATP binding and mechanical action.
Sci Rep, 8, 2018
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4M63
 | | Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | | Authors: | Tomchick, D.R, Zahm, J.A, Rosen, M.K. | | Deposit date: | 2013-08-08 | | Release date: | 2013-10-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.748 Å) | | Cite: | The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
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2C9O
 | | 3D Structure of the human RuvB-like helicase RuvBL1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RUVB-LIKE 1 | | Authors: | Matias, P.M, Gorynia, S, Donner, P, Carrondo, M.A. | | Deposit date: | 2005-12-14 | | Release date: | 2006-10-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006
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4JHD
 | | Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu | | Descriptor: | Actin-5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Chen, X, Ni, F, Wang, Q. | | Deposit date: | 2013-03-04 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structural basis of actin filament nucleation by tandem w domains.
Cell Rep, 3, 2013
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2HF4
 | | Crystal structure of Monomeric Actin in its ATP-bound state | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION | | Authors: | Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M. | | Deposit date: | 2006-06-22 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
J.Biol.Chem., 281, 2006
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4C5I
 | | Crystal structure of MBTD1 YY1 complex | | Descriptor: | MBT DOMAIN-CONTAINING PROTEIN 1, TRANSCRIPTIONAL REPRESSOR PROTEIN YY1 | | Authors: | Alfieri, C, Glatt, S, Mueller, C.W. | | Deposit date: | 2013-09-12 | | Release date: | 2013-11-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.586 Å) | | Cite: | Structural Basis for Targeting the Chromatin Repressor Sfmbt to Polycomb Response Elements
Genes Dev., 27, 2013
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5WFN
 | | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | | Descriptor: | Actin-5C, Leiomodin-2, MAGNESIUM ION, ... | | Authors: | Yurtsever, Z, Eck, M.J, Dominguez, R. | | Deposit date: | 2017-07-12 | | Release date: | 2017-08-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
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2HF3
 | | Crystal structure of monomeric Actin in the ADP bound state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-5C, CALCIUM ION | | Authors: | Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M. | | Deposit date: | 2006-06-22 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
J.Biol.Chem., 281, 2006
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6BGH
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6BGG
 | | Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide | | Descriptor: | Bromodomain-containing protein 3, CHD4 | | Authors: | Wai, D.C.C, Szyszka, T.N, Campbell, A.E, Kwong, C, Wilkinson-White, L, Silva, A.P.G, Low, J.K.K, Kwan, A.H, Gamsjaeger, R, Lu, B, Vakoc, C.R, Blobel, G.A, Mackay, J.P. | | Deposit date: | 2017-10-28 | | Release date: | 2018-03-21 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.
J. Biol. Chem., 293, 2018
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5FM6
 | | Double-heterohexameric rings of full-length Rvb1(ADP)Rvb2(apo) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, RVB1, ... | | Authors: | Silva-Martin, N, Dauden, M.I, Glatt, S, Hoffmann, N.A, Mueller, C.W. | | Deposit date: | 2015-11-02 | | Release date: | 2016-01-20 | | Method: | X-RAY DIFFRACTION (2.997 Å) | | Cite: | The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight Into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex.
Plos One, 11, 2016
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5FM7
 | | Double-heterohexameric rings of full-length Rvb1(ADP)Rvb2(ADP) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RVB1, RVB2 | | Authors: | Silva-Martin, N, Dauden, M.I, Glatt, S, Hoffmann, N.A, Mueller, C.W. | | Deposit date: | 2015-11-02 | | Release date: | 2016-01-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.901 Å) | | Cite: | The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight Into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex.
Plos One, 11, 2016
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5Y81
 | | NuA4 TEEAA sub-complex | | Descriptor: | Actin, Actin-related protein 4, Chromatin modification-related protein EAF1, ... | | Authors: | Wang, X, Cai, G. | | Deposit date: | 2017-08-18 | | Release date: | 2018-04-18 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex
Nat Commun, 9, 2018
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5SVA
 | | Mediator-RNA Polymerase II Pre-Initiation Complex | | Descriptor: | 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... | | Authors: | Robinson, P.J, Bushnell, D.A, Kornberg, R.D. | | Deposit date: | 2016-08-05 | | Release date: | 2016-09-28 | | Last modified: | 2019-11-27 | | Method: | ELECTRON MICROSCOPY (15.3 Å) | | Cite: | Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
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