6BGG

Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide

Summary for 6BGG

• Entry DOI: 10.2210/pdb6bgg/pdb
• NMR Information: BMRB: 30367
• Descriptor: CHD4, Bromodomain-containing protein 3 (2 entities in total)
• Functional Keywords: transcription regulation, epigenetics, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 11961.58

Authors

Wai, D.C.C.,Szyszka, T.N.,Campbell, A.E.,Kwong, C.,Wilkinson-White, L.,Silva, A.P.G.,Low, J.K.K.,Kwan, A.H.,Gamsjaeger, R.,Lu, B.,Vakoc, C.R.,Blobel, G.A.,Mackay, J.P. (deposition date: 2017-10-28, release date: 2018-03-21, Last modification date: 2024-05-15)

• Primary citation: Wai, D.C.C.,Szyszka, T.N.,Campbell, A.E.,Kwong, C.,Wilkinson-White, L.E.,Silva, A.P.G.,Low, J.K.K.,Kwan, A.H.,Gamsjaeger, R.,Chalmers, J.D.,Patrick, W.M.,Lu, B.,Vakoc, C.R.,Blobel, G.A.,Mackay, J.P.; The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.; J. Biol. Chem., 293:7160-7175, 2018; PubMed: 29567837; DOI: 10.1074/jbc.RA117.000678

Experimental method

SOLUTION NMR