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6CTX
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BU of 6ctx by Molmil
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CBr2, beta, gamma dCTP analogue
Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-deoxy-5'-O-[(R)-{[(R)-[dibromo(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2018-03-23
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
6QG1
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BU of 6qg1 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
4K4I
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BU of 4k4i by Molmil
Ternary crystal structures of a human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)FTC-TP.
Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Vyas, R, Suo, Z.
Deposit date:2013-04-12
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda.
Proc.Natl.Acad.Sci.USA, 111, 2014
4K4G
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BU of 4k4g by Molmil
Ternary crystal structures of human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND L-DCTP.
Descriptor: 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, ACETATE ION, CACODYLATE ION, ...
Authors:Vyas, R, Suo, Z.
Deposit date:2013-04-12
Release date:2014-07-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda.
Proc.Natl.Acad.Sci.USA, 111, 2014
6QG2
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BU of 6qg2 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG6
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BU of 6qg6 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (10.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG0
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BU of 6qg0 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG3
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BU of 6qg3 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG5
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BU of 6qg5 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
4K4H
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BU of 4k4h by Molmil
Ternary crystal structures of a human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)3TC-TP.
Descriptor: ACETATE ION, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ...
Authors:Vyas, R, Suo, Z.
Deposit date:2013-04-12
Release date:2014-07-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda.
Proc.Natl.Acad.Sci.USA, 111, 2014
4R63
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BU of 4r63 by Molmil
Binary complex crystal structure of R258A mutant of DNA polymerase Beta
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Batra, V.K, Beard, W.A, Wilson, S.H.
Deposit date:2014-08-22
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
6FEC
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BU of 6fec by Molmil
Human cap-dependent 48S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schaffitzel, C, Schaffitzel, C.
Deposit date:2017-12-31
Release date:2018-03-14
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structure of a human cap-dependent 48S translation pre-initiation complex.
Nucleic Acids Res., 46, 2018
4F02
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BU of 4f02 by Molmil
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
Descriptor: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Safaee, N, Kozlov, G, Gehring, K.B.
Deposit date:2012-05-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4R64
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BU of 4r64 by Molmil
Binary complex crystal structure of E295K mutant of DNA polymerase Beta
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Batra, V.K, Beard, W.A, Wilson, S.H.
Deposit date:2014-08-22
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
1J1C
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BU of 1j1c by Molmil
Binary complex structure of human tau protein kinase I with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase kinase-3 beta, MAGNESIUM ION
Authors:Aoki, M, Yokota, T, Sugiura, I, Sasaki, C, Hasegawa, T, Okumura, C, Kohno, T, Sugio, S, Matsuzaki, T.
Deposit date:2002-12-03
Release date:2003-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
4R66
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BU of 4r66 by Molmil
Ternary complex crystal structure of E295K mutant of DNA polymerase Beta
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Batra, V.K, Beard, W.A, Wilson, S.H.
Deposit date:2014-08-22
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
4R65
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BU of 4r65 by Molmil
Ternary complex crystal structure of R258A mutant of DNA polymerase Beta
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Batra, V.K, Beard, W.A, Wilson, S.H.
Deposit date:2014-08-22
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014
5J2K
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BU of 5j2k by Molmil
Ternary complex crystal structure of DNA polymerase Beta with T:T mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J29
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BU of 5j29 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with A:A mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase beta, Downstream Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2G
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BU of 5j2g by Molmil
Ternary complex crystal structure of DNA polymerase Beta with G:G mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2E
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BU of 5j2e by Molmil
Ternary complex crystal structure of DNA polymerase Beta with C:T mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2C
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BU of 5j2c by Molmil
Ternary complex crystal structure of DNA polymerase Beta with C:A mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2J
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BU of 5j2j by Molmil
Ternary complex crystal structure of DNA polymerase Beta with T:G mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2A
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BU of 5j2a by Molmil
Ternary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J2F
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BU of 5j2f by Molmil
Ternary complex crystal structure of DNA polymerase Beta with G:A mismatch at the primer terminus
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-29
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016

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數據於2024-10-16公開中

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