Ternary complex crystal structure of DNA polymerase Beta with A:A mismatch at the primer terminus

Summary for 5J29

Related5J0O 5J0P 5J0Q 5J0R 5J0S 5J0T 5J0U 5J0V 5J0W 5J0X 5J0Y 5J2A 5J2B 5J2C 5J2D 5J2E 5J2F 5J2G 5J2H 5J2I 5J2J 5J2K
DescriptorDNA polymerase beta, Template Strand, Primer Strand, ... (8 entities in total)
Functional Keywordsdna polymerase beta, mismatch extension, ternary complex, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight48261.64
Batra, V.K.,Wilson, S.H. (deposition date: 2016-03-29, release date: 2016-10-26, Last modification date: 2016-11-09)
Primary citation
Batra, V.K.,Beard, W.A.,Pedersen, L.C.,Wilson, S.H.
Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24:1863-1875, 2016
PubMed: 27642161 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2016.08.006
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2597 0.6% 1.4% 2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21