3ONF
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![BU of 3onf by Molmil](/molmil-images/mine/3onf) | Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with cordycepin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3'-DEOXYADENOSINE, Adenosylhomocysteinase, ... | Authors: | Brzezinski, K, Jaskolski, M. | Deposit date: | 2010-08-28 | Release date: | 2011-08-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr.,Sect.D, 68, 2012
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6BU9
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![BU of 6bu9 by Molmil](/molmil-images/mine/6bu9) | Drosophila Dicer-2 bound to blunt dsRNA | Descriptor: | Dicer-2, isoform A, RNA (5'-R(*AP*CP*UP*AP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*C)-3'), ... | Authors: | Shen, P.S, Sinha, N.K, Bass, B.L. | Deposit date: | 2017-12-09 | Release date: | 2017-12-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
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6BK4
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3OND
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![BU of 3ond by Molmil](/molmil-images/mine/3ond) | Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with adenosine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, Adenosylhomocysteinase, ... | Authors: | Brzezinski, K, Jaskolski, M. | Deposit date: | 2010-08-28 | Release date: | 2011-08-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr.,Sect.D, 68, 2012
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6BBF
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3L4X
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![BU of 3l4x by Molmil](/molmil-images/mine/3l4x) | Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8 | Descriptor: | (1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sim, L, Rose, D.R. | Deposit date: | 2009-12-21 | Release date: | 2010-02-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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4KZN
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![BU of 4kzn by Molmil](/molmil-images/mine/4kzn) | crystal structure of human VEGF-A receptor binding domain | Descriptor: | SULFATE ION, TRIETHYLENE GLYCOL, Vascular endothelial growth factor A, ... | Authors: | Liaw, Y.C. | Deposit date: | 2013-05-30 | Release date: | 2014-06-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7114 Å) | Cite: | Structural Basis for the Bivalent Glycosylated Human VEGF-A121 and VEGF-A165 in recruiment of Receptor and Co-receptor to be published
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3L4T
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![BU of 3l4t by Molmil](/molmil-images/mine/3l4t) | Crystal complex of N-terminal Human Maltase-Glucoamylase with BJ2661 | Descriptor: | (1R,2S)-1-[(1S)-1,2-dihydroxyethyl]-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-2-hydroxypropyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltase-glucoamylase, ... | Authors: | Sim, L, Rose, D.R. | Deposit date: | 2009-12-21 | Release date: | 2010-02-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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8DMH
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![BU of 8dmh by Molmil](/molmil-images/mine/8dmh) | Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28 | Descriptor: | 18.5C-M28 Fab Heavy Chain, 18.5C-M28 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | Deposit date: | 2022-07-08 | Release date: | 2023-04-12 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus. Cell Chem Biol, 30, 2023
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8DMI
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![BU of 8dmi by Molmil](/molmil-images/mine/8dmi) | Lymphocytic choriomeningitis virus glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G1, ... | Authors: | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | Deposit date: | 2022-07-08 | Release date: | 2023-04-12 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus. Cell Chem Biol, 30, 2023
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4NGT
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![BU of 4ngt by Molmil](/molmil-images/mine/4ngt) | Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Tykvart, J, Pachl, P. | Deposit date: | 2013-11-02 | Release date: | 2014-06-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg.Med.Chem., 22, 2014
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4NGP
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![BU of 4ngp by Molmil](/molmil-images/mine/4ngp) | Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Tykvart, J, Pachl, P. | Deposit date: | 2013-11-02 | Release date: | 2014-06-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg.Med.Chem., 22, 2014
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7EDR
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![BU of 7edr by Molmil](/molmil-images/mine/7edr) | |
4NPP
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![BU of 4npp by Molmil](/molmil-images/mine/4npp) | The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms | Descriptor: | NICKEL (II) ION, Proton-gated ion channel | Authors: | Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M. | Deposit date: | 2013-11-22 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111, 2014
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3J05
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![BU of 3j05 by Molmil](/molmil-images/mine/3j05) | Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab | Descriptor: | envelope protein | Authors: | Teoh, E.P, Kukkaro, P, Teo, E.W, Lim, A, Tan, T.T, Shi, P.Y, Yip, A, Schul, W, Leo, Y.S, Chan, S.H, Smith, K.G.C, Ooi, E.E, Kemeny, D.M, Ng, G, Ng, M.L, Alonso, S, Fisher, D, Hanson, B, Lok, S.M, MacAry, P.A. | Deposit date: | 2011-04-01 | Release date: | 2012-07-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | The structural basis for serotype-specific neutralization of dengue virus by a human antibody. Sci Transl Med, 4, 2012
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8DPM
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8DPL
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3IWW
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![BU of 3iww by Molmil](/molmil-images/mine/3iww) | |
3QIS
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![BU of 3qis by Molmil](/molmil-images/mine/3qis) | Recognition of the F&H motif by the Lowe Syndrome protein OCRL | Descriptor: | Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A | Authors: | Pirruccello, M, Swan, L.E, Folta-Stogniew, E, De Camilli, P. | Deposit date: | 2011-01-27 | Release date: | 2011-06-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Recognition of the F&H motif by the Lowe syndrome protein OCRL. Nat.Struct.Mol.Biol., 18, 2011
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6CGA
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![BU of 6cga by Molmil](/molmil-images/mine/6cga) | Structure of the PR-DUB complex | Descriptor: | Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso | Authors: | Foglizzo, M, Middleton, A.J, Day, C.L, Mace, P.D. | Deposit date: | 2018-02-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes. Nat Commun, 9, 2018
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5DYY
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![BU of 5dyy by Molmil](/molmil-images/mine/5dyy) | Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Coquelle, N, Brus, B, Colletier, J.P. | Deposit date: | 2015-09-25 | Release date: | 2017-01-18 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Development of an in-vivo active reversible butyrylcholinesterase inhibitor. Sci Rep, 6, 2016
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3LPP
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![BU of 3lpp by Molmil](/molmil-images/mine/3lpp) | Crystal complex of N-terminal sucrase-isomaltase with kotalanol | Descriptor: | (1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sim, L, Rose, D.R. | Deposit date: | 2010-02-05 | Release date: | 2010-03-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains. J.Biol.Chem., 285, 2010
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3HIG
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![BU of 3hig by Molmil](/molmil-images/mine/3hig) | |
7EXY
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![BU of 7exy by Molmil](/molmil-images/mine/7exy) | |
4NGN
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![BU of 4ngn by Molmil](/molmil-images/mine/4ngn) | Crystal Structure of Glutamate Carboxypeptidase II in a complex with urea-based inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Tykvart, J, Pachl, P. | Deposit date: | 2013-11-02 | Release date: | 2014-06-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg.Med.Chem., 22, 2014
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