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4OM1
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BU of 4om1 by Molmil
Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ...
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2014-01-25
Release date:2014-09-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.131 Å)
Cite:Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo.
J.Virol., 88, 2014
4W70
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BU of 4w70 by Molmil
Periplasmically Produced Monomeric Single Domain Antibody (sdAb) C22A/C99V variant against Staphylococcal enterotoxin B (SEB) at pH 7.0
Descriptor: SULFATE ION, Single Domain Antibody
Authors:George, J, Legler, P.M.
Deposit date:2014-08-21
Release date:2014-11-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
4W81
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BU of 4w81 by Molmil
Periplasmically Produced Monomeric Single Domain Antibody (sdAb) C22A/C99V variant against Staphylococcal enterotoxin B (SEB) at pH 8.0
Descriptor: SULFATE ION, Single Domain Antibody
Authors:George, J, Legler, P.M.
Deposit date:2014-08-22
Release date:2014-11-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
4G6M
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BU of 4g6m by Molmil
Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab
Descriptor: Interleukin-1 beta, heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment
Authors:Blech, M, Hoerer, S.
Deposit date:2012-07-19
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab
J.Mol.Biol., 425, 2013
4K3E
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BU of 4k3e by Molmil
Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
4YK4
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BU of 4yk4 by Molmil
Human antibody 641 I-9 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 641 I-9 VHCH antibody, 641 I-9 VLCL antibody, ...
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2015-03-03
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Viral receptor-binding site antibodies with diverse germline origins.
Cell, 161, 2015
4FP8
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BU of 4fp8 by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-21
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.947 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4FNL
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BU of 4fnl by Molmil
Crystal structure of broadly neutralizing antibody C05
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Antibody C05, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-19
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
4FQR
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BU of 4fqr by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing antibody C05, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-25
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
3H3B
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BU of 3h3b by Molmil
Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain
Descriptor: Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21
Authors:Zhou, H, Liu, Y, Niu, L, Zhu, J, Teng, M.
Deposit date:2009-04-16
Release date:2010-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21.
J.Biol.Chem., 286, 2011
8VFU
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BU of 8vfu by Molmil
The Fab Crystal Structure of the PAN IL-1 Family Inhibitor Antibody 3G5
Descriptor: 3G5 Heavy Chain, 3G5 Light Chain
Authors:Fields, J.K, Sundberg, E.J.
Deposit date:2023-12-22
Release date:2024-02-21
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling.
Cell Rep, 43, 2024
4WHT
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BU of 4wht by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form
Descriptor: Epitope peptide, Heavy chain of the Fab fragment derived from neutralizing antibody 3/11, Light chain of the Fab fragment derived from neutralizing antibody 3/11
Authors:Krey, T, Rey, F.A.
Deposit date:2014-09-23
Release date:2014-12-17
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies.
J.Virol., 89, 2015
4OII
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BU of 4oii by Molmil
West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab
Descriptor: Heavy Chain of Fab fragment of 22NS1 Antibody, Light Chain of Fab fragment of 22NS1 Antibody, NON-STRUCTURAL PROTEIN NS1
Authors:Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-19
Release date:2014-03-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of Flavivirus NS1 assembly and antibody recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
6U59
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BU of 6u59 by Molmil
HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ...
Authors:Yang, Y.R, Ward, A.B.
Deposit date:2019-08-27
Release date:2020-01-29
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits.
J.Virol., 94, 2020
5TKJ
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BU of 5tkj by Molmil
Structure of vaccine-elicited diverse HIV-1 neutralizing antibody vFP1.01 in complex with HIV-1 fusion peptide residue 512-519
Descriptor: HIV-1 fusion peptide residue 512-519, SULFATE ION, vFP1.01 chimeric mouse antibody heavy chain, ...
Authors:Xu, K, Liu, K, Kwong, P.D.
Deposit date:2016-10-06
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.118 Å)
Cite:Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6DZN
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BU of 6dzn by Molmil
Pan-ebolavirus human antibody ADI-15878 Fab
Descriptor: 2-(2-ETHOXYETHOXY)ETHANOL, Antibody ADI-15878, heavy chain, ...
Authors:Murin, C.D, Ward, A.B, Bruhn, J.F, Stanfield, R.
Deposit date:2018-07-05
Release date:2018-09-12
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop.
Cell Rep, 24, 2018
6ML8
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BU of 6ml8 by Molmil
Crystal structure of hemagglutinin from H1N1 Influenza A virus A/Denver/57 bound to the C05 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 antibody Fab heavy chain, C05 antibody Fab light chain, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-09-27
Release date:2018-10-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site.
Sci Rep, 13, 2023
4K3D
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BU of 4k3d by Molmil
Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
1DSF
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BU of 1dsf by Molmil
THE CRYSTAL STRUCTURE OF THE DISULFIDE-STABILIZED FV FRAGMENT OF ANTICANCER ANTIBODY B1: CONFORMATIONAL INFLUENCE OF AN ENGINEERED DISULFIDE BOND
Descriptor: ANTICANCER ANTIBODY B1
Authors:Almog, O, Gilliland, G.L.
Deposit date:1997-05-04
Release date:1998-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond.
Proteins, 31, 1998
6XPQ
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BU of 6xpq by Molmil
Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: Hemagglutinin, antibody D1 H1-17/H3-14 light chain, antibody D1 H1-17/H3-14 heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ4
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BU of 6xq4 by Molmil
Human antibody S8V2-47 in complex with the influenza hemagglutinin head domain of A/Beijing/262/1995(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, antibody S8V2-47 heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.347 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPR
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BU of 6xpr by Molmil
Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C, Lee, J.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.092 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPZ
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BU of 6xpz by Molmil
Human antibody S1V2-83 in complex with the influenza hemagglutinin head domain of A/Moscow/10/1999(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ0
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BU of 6xq0 by Molmil
Human antibody S8V2-18 in complex with the influenza hemagglutinin head domain of A/California/7/2009(NYMC-X181)(H1N1)
Descriptor: GLYCEROL, Hemagglutinin, antibody S8V2-18 heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ2
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BU of 6xq2 by Molmil
Human antibody S8V2-37 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021

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數據於2024-07-24公開中

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