6DZN

Pan-ebolavirus human antibody ADI-15878 Fab

Summary for 6DZN

Entry DOI	10.2210/pdb6dzn/pdb
Descriptor	Antibody ADI-15878, light chain, Antibody ADI-15878, heavy chain, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	adi-15878, antibody, pan-ebolavirus, immunotherapeutic, ebola virus, bundibugyo virus, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	47658.58
Authors	Murin, C.D.,Ward, A.B.,Bruhn, J.F.,Stanfield, R. (deposition date: 2018-07-05, release date: 2018-09-12, Last modification date: 2019-12-18)
Primary citation	Murin, C.D.,Bruhn, J.F.,Bornholdt, Z.A.,Copps, J.,Stanfield, R.,Ward, A.B. Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop. Cell Rep, 24:2723-2732.e4, 2018 Cited by PubMed: 30184505 DOI: 10.1016/j.celrep.2018.08.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation