PDB: 26816 resultsInfo pagesStatus searchChemie searchBIRD

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2JT0	Solution structure of F104W cardiac troponin C Descriptor: Troponin C, slow skeletal and cardiac muscles Authors: Wang, X, Mercier, P, Letourneau, P.-J, Sykes, B.D. Deposit date: 2007-07-17 Release date: 2008-05-27 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Sci., 14, 2005
6AMH	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Ser bound as E(Aex1) Descriptor: SODIUM ION, Tryptophan synthase beta chain 1, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE Authors: Buller, A.R. Deposit date: 2017-08-09 Release date: 2018-05-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AM7	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9 Descriptor: PHOSPHATE ION, SODIUM ION, Tryptophan synthase beta chain 1 Authors: Buller, A.R, van Roye, P. Deposit date: 2017-08-09 Release date: 2018-05-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AMC	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 Descriptor: SODIUM ION, Tryptophan synthase beta chain 1 Authors: Buller, A.R, Herger, M. Deposit date: 2017-08-09 Release date: 2018-05-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AM9	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser-bound in a predominantly closed state. Descriptor: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, SODIUM ION, Tryptophan synthase beta chain 1, ... Authors: Buller, A.R, van Roye, P. Deposit date: 2017-08-09 Release date: 2018-05-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
5TCH	Crystal structure of tryptophan synthase from M. tuberculosis - ligand-free form, TrpA-G66V mutant Descriptor: FORMIC ACID, MALONATE ION, Tryptophan synthase alpha chain, ... Authors: Michalska, K, Maltseva, N, Jedrzejczak, R, Wellington, S, Nag, P.P, Fisher, S.L, Schreiber, S.L, Hung, D.T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2016-09-15 Release date: 2017-05-31 Last modified: 2022-04-13 Method: X-RAY DIFFRACTION (2.35 Å) Cite: A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase. Nat. Chem. Biol., 13, 2017
1ZBC	Crystal Structure of the porcine signalling protein liganded with the peptide Trp-Pro-Trp (WPW) at 2.3 A resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3 mer peptide, signal processing protein Authors: Srivastava, D.B, Kaur, P, Kumar, J, Somvanshi, R.K, Sharma, S, Dey, S, Singh, T.P. Deposit date: 2005-04-08 Release date: 2005-04-19 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Crystal Structure of the porcine signalling protein liganded with the peptide Trp-Pro-Trp (WPW) at 2.3 A resolution To be Published
6HBW	Crystal structure of deoxy-human hemoglobin beta6 glu->trp Descriptor: PROTEIN (HEMOGLOBIN ALPHA 1), PROTEIN (HEMOGLOBIN BETA), PROTOPORPHYRIN IX CONTAINING FE Authors: Harrington, D.J, Adachi, K, Royer Jr, W.E. Deposit date: 1998-09-10 Release date: 1998-09-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiber. J.Biol.Chem., 273, 1998
1GHD	Crystal structure of the glutaryl-7-aminocephalosporanic acid acylase by mad phasing Descriptor: GLUTARYL-7-AMINOCEPHALOSPORANIC ACID ACYLASE Authors: Ding, Y, Jiang, W, Mao, X, He, H, Zhang, S, Tang, H, Bartlam, M, Ye, S, Jiang, F, Liu, Y, Zhao, G, Rao, Z. Deposit date: 2000-12-07 Release date: 2003-07-08 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Affinity alkylation of the Trp-B4 residue of the beta -subunit of the glutaryl 7-aminocephalosporanic acid acylase of Pseudomonas sp. 130. J.Biol.Chem., 277, 2002
8I2J	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1-(4-methoxyphenyl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.65 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I27	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, 4-methoxybenzenecarbonitrile, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2A	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, 5-METHOXYBENZIMIDAZOLE, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.35 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2M	The crystal structure of homodimeric E. coli tryptophanyl-tRNA synthetase bound with niraparib at one of its two active sites Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, SULFATE ION, TRYPTOPHANYL-5'AMP, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2C	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, 4-methoxyaniline, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.07 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I1Z	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment Descriptor: 1-(2,3-dihydro-1-benzofuran-5-yl)ethanone, SULFATE ION, TRYPTOPHANYL-5'AMP, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-13 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
8I2L	E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface Descriptor: 1,2-ETHANEDIOL, CHLORZOXAZONE, SULFATE ION, ... Authors: Xiang, M, Zhou, H. Deposit date: 2023-01-14 Release date: 2023-04-12 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic Acids Res., 51, 2023
1RVW	R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY Descriptor: CARBON MONOXIDE, HEMOGLOBIN, PHOSPHATE ION, ... Authors: Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. Deposit date: 1997-03-20 Release date: 1998-03-25 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
5HUC	DAHP synthase from Corynebacterium glutamicum Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, MANGANESE (II) ION, ... Authors: Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U. Deposit date: 2016-01-27 Release date: 2017-08-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp. Biochemistry, 57, 2018
5HUE	DAHP synthase from Corynebacterium glutamicum in complex with tryptophan Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, ... Authors: Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U. Deposit date: 2016-01-27 Release date: 2017-08-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp. Biochemistry, 57, 2018
2OH9	Myoglobin cavity mutant V68W Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Phillips Jr, G.N, Li, T, Brucker, E.A, Soman, J, Olson, J.S. Deposit date: 2007-01-09 Release date: 2007-01-23 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Ligand pathways in myoglobin: A review of trp cavity mutations. Iubmb Life, 59, 2007
7QRI	Regulatory domain dimer of tryptophan hydroxylase 2 in complex with L-Phe Descriptor: PHENYLALANINE, Tryptophan 5-hydroxylase 2 Authors: Vedel, I.M, Prestel, A, Harris, P, Peters, G.H.J, Kragelund, B.B. Deposit date: 2022-01-11 Release date: 2023-05-03 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand. Structure, 31, 2023
7RJ1	Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chorismate mutase, ... Authors: Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2021-07-20 Release date: 2021-07-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp To Be Published
1PWU	Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases. Descriptor: 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, Lethal factor, ZINC ION Authors: Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. Deposit date: 2003-07-02 Release date: 2004-02-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat.Struct.Mol.Biol., 11, 2004
1J9N	Solution Structure of the Nucleopeptide [AC-LYS-TRP-LYS-HSE(p3*dGCATCG)-ALA]-[p5*dCGTAGC] Descriptor: 5'-D(*CP*GP*TP*AP*GP*C)-3', 5'-D(*GP*CP*TP*AP*CP*(PGN))-3', peptide ACE-LYS-TRP-LYS-HSE-ALA Authors: Gomez-Pinto, I, Marchan, V, Gago, F, Grandas, A, Gonzalez, C. Deposit date: 2001-05-28 Release date: 2003-01-21 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Solution structure and stability of tryptophan-containing nucleopeptide duplexes Chembiochem, 4, 2003
6IQY	High resolution structure of bilirubin oxidase from Myrothecium verrucaria - M467Q mutant, anaerobically prepared Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Bilirubin oxidase, ... Authors: Shibata, N, Akter, M, Higuchi, Y. Deposit date: 2018-11-09 Release date: 2018-11-21 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Redox Potential-Dependent Formation of an Unusual His-Trp Bond in Bilirubin Oxidase. Chemistry, 24, 2018

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