7QRI
Regulatory domain dimer of tryptophan hydroxylase 2 in complex with L-Phe
Summary for 7QRI
| Entry DOI | 10.2210/pdb7qri/pdb |
| NMR Information | BMRB: 34698 |
| Descriptor | Tryptophan 5-hydroxylase 2, PHENYLALANINE (2 entities in total) |
| Functional Keywords | tryptophan hydroxylase 2, serotonin biosynthesis, aromatic amino acid hydroxylase, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 22898.10 |
| Authors | Vedel, I.M.,Prestel, A.,Harris, P.,Peters, G.H.J.,Kragelund, B.B. (deposition date: 2022-01-11, release date: 2023-05-03, Last modification date: 2023-06-14) |
| Primary citation | Vedel, I.M.,Prestel, A.,Zhang, Z.,Skawinska, N.T.,Stark, H.,Harris, P.,Kragelund, B.B.,Peters, G.H.J. Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand. Structure, 31:689-, 2023 Cited by PubMed: 37119821DOI: 10.1016/j.str.2023.04.004 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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