7P0N

Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the open conformation

Summary for 7P0N

Entry DOI	10.2210/pdb7p0n/pdb
Descriptor	Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, N'-Formylkynurenine, ... (9 entities in total)
Functional Keywords	l-trp metabolism, hemoprotein, dynamics loop, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	187517.93
Authors	Mirgaux, M.,Wouters, J. (deposition date: 2021-06-30, release date: 2021-12-29, Last modification date: 2024-01-31)
Primary citation	Mirgaux, M.,Leherte, L.,Wouters, J. Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14:11786469211052964-11786469211052964, 2021 Cited by PubMed: 34949925 DOI: 10.1177/11786469211052964 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation