5DW0
TrpB from Pyrococcus furiosus with L-serine bound as the external aldimine
Summary for 5DW0
Entry DOI | 10.2210/pdb5dw0/pdb |
Related | 5DVZ 5DW3 5E0K |
Descriptor | Tryptophan synthase beta chain 1, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE, SODIUM ION, ... (4 entities in total) |
Functional Keywords | plp, external aldimine, pr, lyase |
Biological source | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
Total number of polymer chains | 4 |
Total formula weight | 176064.60 |
Authors | Buller, A.R.,Arnold, F.H. (deposition date: 2015-09-22, release date: 2015-11-11, Last modification date: 2024-03-06) |
Primary citation | Buller, A.R.,Brinkmann-Chen, S.,Romney, D.K.,Herger, M.,Murciano-Calles, J.,Arnold, F.H. Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation. Proc.Natl.Acad.Sci.USA, 112:14599-14604, 2015 Cited by PubMed: 26553994DOI: 10.1073/pnas.1516401112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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